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Kefir exhibits anti‑proliferative and pro‑apoptotic effects on colon adenocarcinoma cells with no significant effects on cell migration and invasion
Published 2014“…Western blotting results revealed an upregulation in Bax:Bcl‑2 ratio, confirming the pro‑apoptotic effect of kefir, and an increase in p53 independent‑p21 expression upon kefir treatment. …”
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The Anti-Tumor Agent Sodium Selenate Decreases Methylated PP2A, Increases GSK3βY216 Phosphorylation, Including Tau Disease Epitopes and Reduces Neuronal Excitability in SHSY-5Y Neu...
Published 2019“…Somewhat surprisingly, the catalytically active form, methylated PP2A (mePP2A) was significantly decreased. In close correlation to these data, the phosphorylation state of two substrate proteins, sensitive to PP2A activity, GSK3β and Tau were found to be increased. …”
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Quantified Database for Methane Dehydroaromatization Reaction
Published 2022“…There is an increasing interest in this reaction evident by a large number of literature and patents published so far. …”
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A slow but steady nanoLuc: R162A mutation results in a decreased, but stable, nanoLuc activity
Published 2024“…This is specifically relevant in designing assays that require bioluminescence for extended periods, such as in the case of biosensors designed for monitoring slow enzymatic or <u>cellular signaling</u> reactions, without necessitating multiple rounds of luciferase substrate addition or any specialized reagents that result in increased assay costs. …”
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Decreased Interfacial Dynamics Caused by the N501Y Mutation in the SARS-CoV-2 S1 Spike:ACE2 Complex
Published 2022“…In this regard, the recent SARS-CoV-2 alpha, beta, and gamma variants (B.1.1.7, B.1.351, and P.1 lineages, respectively) are of great significance in that they contain several mutations that increase their transmission rates as evident from clinical reports. …”
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Daucus carota pentane-based fractions arrest the cell cycle and increase apoptosis in MDA-MB-231 breast cancer cells
Published 2014“…The increase in apoptosis in response to treatment was also apparent in the increase in BAX and the decrease in Bcl-2 levels as well as the proteolytic cleavage of both caspase-3 and PARP as revealed by Western blot. …”
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Factors that influence patient and public adverse drug reaction reporting: a systematic review using the theoretical domains framework
Published 2023“…<h3>Background</h3><p dir="ltr">Only 5–10% of all adverse drug reactions (ADRs) are reported. Mechanisms to support patient and public reporting offer numerous advantages to health care systems including increasing reporting rate. …”
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In-situ grown ternary metal hydroxides@3D oriented crumpled V₂C MXene sheets for improved electrocatalytic oxygen evolution reaction
Published 2024“…In essence, this study features a facile approach for the confined growth of multi transition metal hydroxides in the presence of morphologically unique 3D crumpled V₂C MXene architectures. Consequently, the increased OER reaction kinetics and improved stability of the synthesized composites are potentially due to synergistic interplay between well dispersed active sites and the conductive substrate.…”
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A population study of clinically actionable genetic variation affecting drug response from the Middle East
Published 2022“…The allele frequencies of 1,320 variants in 703 genes affecting 299 drugs or class of drugs were significantly different between the Qatari population and other world populations. …”
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Theoretical insight into effect of cation–anion pairs on CO<sub>2</sub> reduction on bismuth electrocatalysts
Published 2020“…The adsorption energy (Eads) and work function (Wf) of the anions increases with decreasing anion size (i.e., Cl<sup>−</sup> > Br<sup>−</sup> > I<sup>−</sup>). …”
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Formation of Trihalomethanes during Seawater Chlorination
Published 2010“…Chlorination of seawater has shown significant increase in total THMs (TTHMs) and in bromoform concentrations. …”
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Assessment of Brain Function After 240 Days Confinement Using Functional Near Infrared Spectroscopy
Published 2024“…The FCN shows a significant decrease in most of the right frontal areas. …”
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