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Reduction of laboratory utilization in the intensive care unit
Published 2016“…Conclusion: A simple technique of resident, nursing, and ancillary staff education, combined with alterations in order sets using electronic medical records, can lead to a sustained reduction in laboratory test utilization over time and to significant cost savings without affecting patient safety.…”
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A slow but steady nanoLuc: R162A mutation results in a decreased, but stable, nanoLuc activity
Published 2024“…However, questions related to its mechanism of interaction with the substrate, furimazine, as well as bioluminescence activity remain elusive. Here, we combined molecular dynamics (MD) simulation and mutational analysis to show that the R162A mutation results in a decreased but stable <u>bioluminescence </u>activity of NLuc in living cells and in vitro. …”
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Decreased Interfacial Dynamics Caused by the N501Y Mutation in the SARS-CoV-2 S1 Spike:ACE2 Complex
Published 2022“…Additionally, we find that the N501Y mutant S1-RBD displays altered dynamics that likely aids in its enhanced interaction with ACE2. …”
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Performance evaluation of 3D-printed PLA composites doped with WE43 magnesium alloy for bone tissue engineering applications
Published 2025“…While a low Mg content (5 %) only slightly impacted the print quality and dimensions, higher Mg concentrations (10 % and 15 %) led to increased weight, rougher surfaces, dimensional shrinkage in height, and overall poorer formation quality. Adding WE43 alloy to PLA decreased the average pore sizes of the composites. …”
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Notch Signaling Inhibition by LY411575 Attenuates Osteoblast Differentiation and Decreased Ectopic Bone Formation Capacity of Human Skeletal (Mesenchymal) Stem Cells
Published 2019“…Among the tested molecules, LY411575, a potent γ-secretase and Notch signaling inhibitor, exhibited significant inhibitory effects on osteoblastic differentiation of hBMSCs manifested by reduced ALP activity, mineralized matrix formation, and decreased osteoblast-specific gene expression as well as in vivo ectopic bone formation. …”
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Trellis coded modulation with outer RS codes for communication overRayleigh fading channels
Published 1993“…Results obtained indicate that the use of the proposed system does provide a significant reduction in the bit error probability while maintaining an acceptable bandwidth efficiency…”
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Electrochemical CO<sub>2</sub> reduction: The role of catholyte-anolyte interactions in formate/formic acid production
Published 2025“…In addition, the best anolyte was selected to conduct an optimization study using response surface methodology as well as to assess the synergy between the anolyte and catholyte concentrations in order to understand their influence on the reduction process. The results show that NaOH outperforms other anolytes over the concentration ranges studied. …”
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Aerosol Optical Thickness over Large Urban Environments of the Arabian Peninsula—Speciation, Variability, and Distributions
Published 2019“…An increase in AOT values between 2005 and 2009 is attributed to increased dust generation from the Sahel region in Northern Africa, and the Fertile Crescent (Syria, Iraq, Jordan) due to an extended dry period. Reductions in local urban emissions are still considered to be efficient measures to improve air quality in these population centers despite the significant contribution of desert dust in the total particulate matter levels in the region.…”
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The Anti-Tumor Agent Sodium Selenate Decreases Methylated PP2A, Increases GSK3βY216 Phosphorylation, Including Tau Disease Epitopes and Reduces Neuronal Excitability in SHSY-5Y Neu...
Published 2019“…Somewhat surprisingly, the catalytically active form, methylated PP2A (mePP2A) was significantly decreased. In close correlation to these data, the phosphorylation state of two substrate proteins, sensitive to PP2A activity, GSK3β and Tau were found to be increased. …”
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The role of ulnar nerve subcutaneous anterior transposition during open reduction and internal fixation of distal humerus fractures: a retrospective cohort study
Published 2022“…Three out of ten cases recovered in the transposition group, and five out of ten cases recovered in the no transposition group over a mean follow-up of 11.2 months (P = 1.00).</p> <h2>Conclusion</h2> <p>We do not recommend performing routine subcutaneous ulnar nerve anterior transposition during ORIF of distal humerus fracture as it was associated with a significant 5-fold increase in ulnar nerve neuropathy.…”
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Indomethacin as a Rescue Therapy for Patent Ductus Arteriosus in Extremely Premature Infants after Failed Ibuprofen Treatment
Published 2023“…While most PDAs close after one 3-day course of either medicine, a repeat course may be necessary before considering surgical ligation for those who remain with hsPDAs. In our practice, we administer one or two courses of ibuprofen followed by a single course of indomethacin if the PDA has not shown closure or decrease in size on the echocardiogram (echo) exam. …”
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Zooming Into Clarity: Image Denoising Through Innovative Autoencoder Architectures
Published 2024“…In the Autism Face dataset, the FragmentumZoom 4X autoencoder recorded PSNR values of 30.951, with an increase of 1.289 dB over the baseline, and SSIM values of 0.906. These results underscore the efficacy of these novel architectures in improving image quality and advancing image processing techniques, particularly in scenarios requiring heightened resolution and noise reduction.…”
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Novel Enzyme-Free Multifunctional Bentonite/Polypyrrole/Silver Nanocomposite Sensor for Hydrogen Peroxide Detection over a Wide pH Range
Published 2019“…<p dir="ltr">Precise designs of low-cost and efficient catalysts for the detection of hydrogen peroxide (H<sub>2</sub>O<sub>2</sub>) over wide ranges of pH are important in various environmental applications. …”
