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The Anti-Tumor Agent Sodium Selenate Decreases Methylated PP2A, Increases GSK3βY216 Phosphorylation, Including Tau Disease Epitopes and Reduces Neuronal Excitability in SHSY-5Y Neu...
Published 2019“…Somewhat surprisingly, the catalytically active form, methylated PP2A (mePP2A) was significantly decreased. In close correlation to these data, the phosphorylation state of two substrate proteins, sensitive to PP2A activity, GSK3β and Tau were found to be increased. …”
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A slow but steady nanoLuc: R162A mutation results in a decreased, but stable, nanoLuc activity
Published 2024“…Here, we combined molecular dynamics (MD) simulation and mutational analysis to show that the R162A mutation results in a decreased but stable <u>bioluminescence </u>activity of NLuc in living cells and in vitro. …”
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An innovative simulated annealing approach to the long-term hydroscheduling problem
Published 2001“…An adaptive cooling schedule and a new method for variables discretization are implemented to enhance the speed and convergence of the original SAA. A significant reduction in the number of the objective function evaluations, and consequently less iterations are required to reach the optimal solution. …”
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Decreased Interfacial Dynamics Caused by the N501Y Mutation in the SARS-CoV-2 S1 Spike:ACE2 Complex
Published 2022“…In this regard, the recent SARS-CoV-2 alpha, beta, and gamma variants (B.1.1.7, B.1.351, and P.1 lineages, respectively) are of great significance in that they contain several mutations that increase their transmission rates as evident from clinical reports. …”
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Long-term treatment issues with chromite ore processing residue (COPR)
Published 2007“…However, the Cr6+ concentration from the sample with the smaller particle size approached 240 mg/kg (338 mg/kg), suggesting that particle size reduction prior to the addition of reductant may improve the effectiveness of the treatment. …”
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Kefir exhibits anti‑proliferative and pro‑apoptotic effects on colon adenocarcinoma cells with no significant effects on cell migration and invasion
Published 2014“…Results from RT‑PCR showed that kefir decreases the expression of transforming growth factor α (TGF‑α); and transforming growth factor‑β1 (TGF‑β1) in HT‑29 cells. …”
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A new tabu search algorithm for the long-term hydro scheduling problem
Published 2002“…The proposed implementation contributes to the enhancement of speed and convergence of the original tabu search algorithm (TSA). A significant reduction in the objective function over previous classical optimization methods and a simulated annealing algorithm has been achieved. …”
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A comparison of peer, teacher and self-feedback on the reduction of language errors in student essays
Published 2016“…Comparison of students' performance on pronoun agreement errors revealed that all groups increased the percentage of this error on the immediate post-test but decreased it on the delayed post-test, with no significant difference between the groups. …”
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Improved Cognitive Vigilance Assessment after Artifact Reduction with Wavelet Independent Component Analysis
Published 2022“…Our classification results showed that in terms of features extraction, the wICA method outperformed the existing ICA method. …”
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Daucus carota pentane-based fractions arrest the cell cycle and increase apoptosis in MDA-MB-231 breast cancer cells
Published 2014“…The increase in apoptosis in response to treatment was also apparent in the increase in BAX and the decrease in Bcl-2 levels as well as the proteolytic cleavage of both caspase-3 and PARP as revealed by Western blot. …”
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