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Notch Signaling Inhibition by LY411575 Attenuates Osteoblast Differentiation and Decreased Ectopic Bone Formation Capacity of Human Skeletal (Mesenchymal) Stem Cells
Published 2019“…Among the tested molecules, LY411575, a potent γ-secretase and Notch signaling inhibitor, exhibited significant inhibitory effects on osteoblastic differentiation of hBMSCs manifested by reduced ALP activity, mineralized matrix formation, and decreased osteoblast-specific gene expression as well as in vivo ectopic bone formation. …”
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A slow but steady nanoLuc: R162A mutation results in a decreased, but stable, nanoLuc activity
Published 2024“…In this regard, engineering of brighter bioluminescent proteins, i.e. luciferases, has played a significant role. This is acutely exemplified by the engineering of the NLuc <u>luciferase</u>, which is small in size and displays much enhanced bioluminescence and<u> thermal stability</u> compared to previously available luciferases. …”
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Turkronicles: diachronic resources for the fast evolving Turkish language
Published 2025“…Specifically, we show that vocabulary divergence increases over time, as expected. Due to such significant vocabulary change in Turkish over time, similarity between the periods 1920–1929 and 2010–2019 is 57%. …”
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Natural resource dependence and war nexus: new insights
Published 2025“…Using a panel probit model, we find that natural resources rents, military expenditures, and the presence of a common law tradition significantly increase the probability of war occurrence. …”
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The retention of health human resources in primary healthcare centers in Lebanon
Published 2012“…Background Critical shortages of health human resources (HHR), associated with high turnover rates, have been a concern in many countries around the globe. …”
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The landscape of PreK-12 engineering online resources for teachers
Published 2015“…Although professional development offered by universities, school districts, and other educational entities provides the primary source of formal learning tools for teachers, an increasing number of teachers also utilize other informal web-based resources regularly. …”
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Security Assessment of Low-Resource Edge Devices for IoT Systems
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A system dynamics approach to management of water resources in Qatar
Published 2024“…Additionally, to aid policymakers in fostering water resource sustainability, groundwater conservation strategies are proposed using the unique scenario design framework by limiting the yield to the safe abstraction level and emphasizing the significance of preserving non-renewable groundwater resources as a “backstop” resource for the country. …”
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Small molecule inhibition of stat3 enhances survival in mice with intracerebral melanoma
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Intelligent scaling for 6G IoE services for resource provisioning
Published 2021“…Although the demand for change in service from different sectors, the increase in IoE, the limitation of available computing resources of MEC, and intelligent resource solutions are getting much more significant. …”
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Suppression of Unstable Flow by Using Rough Surfaces at Small Mass Flow Rates in a Radial Diffuser
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Innovation Ecosystem for Resource-Rich Countries: Validation of Entrepreneurship Framework for Qatar as a Case
Published 2024“…<p dir="ltr">This study investigated how entrepreneurship can reshape resource-based countries such as Qatar into more diverse, sustainable, and knowledge-driven economies. …”
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LightEnsemble-Guard: An Optimized Ensemble Learning Framework for Securing Resource-Constrained IoT Systems
Published 2025“…<p dir="ltr">The rapid proliferation of real-time Internet of Things (IoT) devices has increased the need for efficient and accurate security mechanisms. …”
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Optimizing the number of players and training bout durations in soccer small‐sided games: Effects on mood balance and technical performance
Published 2025“…Therefore, coaches should consider longer continuous bouts when planning SSGs‐based training to significantly decrease TMD and enhance technical‐tactical performance in soccer SSGs.…”
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Examining the nexus of mineral resources, technology adoption, and economic expansion in advancing sustainable development in OECD economies
Published 2024“…The results act as a plea for sustainable regulation of finite resources, increased funding in human capital, and a heightened emphasis on research and innovation. …”
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Application of Tools of Quality Function Deployment and Modified Balanced Scorecard for Optimal Allocation of Pavement Management Resources
Published 2020“…Many traditional methods were and are still being used by entities related to pavement management to increase the efficiency of management in decision-making and in coordinating the different activities that have a direct impact on pavement systems. …”
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Morphological changes in amblyopic eyes in choriocapillaris and Sattler’s layer in comparison to healthy eyes, and in retinal nerve fiber layer in comparison to fellow eyes through...
Published 2021“…Results The method of measuring reflectivity is good to excellent reliability for all regions of interest except the fourth. The mean reflectivity of the choriocapillaris and Sattler’s layer in amblyopic eyes were significantly lower than in healthy eyes (p = 0.003 and p = 0.008 respectively). …”
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