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The Anti-Tumor Agent Sodium Selenate Decreases Methylated PP2A, Increases GSK3βY216 Phosphorylation, Including Tau Disease Epitopes and Reduces Neuronal Excitability in SHSY-5Y Neu...
Published 2019“…Somewhat surprisingly, the catalytically active form, methylated PP2A (mePP2A) was significantly decreased. In close correlation to these data, the phosphorylation state of two substrate proteins, sensitive to PP2A activity, GSK3β and Tau were found to be increased. …”
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Optimizing the construction team’s performance The influence of an agile project manager on a construction project team’s Success
Published 2023“…And continuously searching to have a successful construction team translates into following many methods and ways to improve the performance of the individual team members and the performance of the whole team, which can only be achieved through our focus on the basic rules or pillars that play a significant role and influence the efficiency of the construction team…”
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A slow but steady nanoLuc: R162A mutation results in a decreased, but stable, nanoLuc activity
Published 2024“…Here, we combined molecular dynamics (MD) simulation and mutational analysis to show that the R162A mutation results in a decreased but stable <u>bioluminescence </u>activity of NLuc in living cells and in vitro. …”
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Decreased Interfacial Dynamics Caused by the N501Y Mutation in the SARS-CoV-2 S1 Spike:ACE2 Complex
Published 2022“…In this regard, the recent SARS-CoV-2 alpha, beta, and gamma variants (B.1.1.7, B.1.351, and P.1 lineages, respectively) are of great significance in that they contain several mutations that increase their transmission rates as evident from clinical reports. …”
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Rising mortality related to cardiovascular disease and prostate cancer amongst older men across the United States
Published 2024“…<h3>Objective</h3><p dir="ltr">There is a significant association between cardiovascular diseases (CVD) and prostate cancer (PCa), leading to high mortality. …”
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A Correlation between Theoretical and Actual Column Shortening and Lateral Sway in a Vertically Asymmetric High-Rise Concrete Building
Published 2016“…The consideration of columns shortening in high-rise buildings becomes more complex and needs more attention when the building is vertically asymmetric. …”
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Kefir exhibits anti‑proliferative and pro‑apoptotic effects on colon adenocarcinoma cells with no significant effects on cell migration and invasion
Published 2014“…Results from RT‑PCR showed that kefir decreases the expression of transforming growth factor α (TGF‑α); and transforming growth factor‑β1 (TGF‑β1) in HT‑29 cells. …”
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The behavior of Tapered High Strength Concrete Filled Steel Tube (CFST) Column connected to Encased Steel Reinforced Concrete Composite (SRC) Column
Published 2020“…Nowadays, Composite Columns have been widely developed in the construction of the high-rise buildings, long span structures, and bridges. …”
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Daucus carota pentane-based fractions arrest the cell cycle and increase apoptosis in MDA-MB-231 breast cancer cells
Published 2014“…The increase in apoptosis in response to treatment was also apparent in the increase in BAX and the decrease in Bcl-2 levels as well as the proteolytic cleavage of both caspase-3 and PARP as revealed by Western blot. …”
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Email Spam: A Comprehensive Review of Optimize Detection Methods, Challenges, and Open Research Problems
Published 2024“…The volume of spam emails is rising rapidly day by day. Detecting and filtering spam presents significant and complex challenges for email systems. …”
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Impact of Environmental, Social and Governance Factors on Financial Performance in Indian Firms
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