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The Anti-Tumor Agent Sodium Selenate Decreases Methylated PP2A, Increases GSK3βY216 Phosphorylation, Including Tau Disease Epitopes and Reduces Neuronal Excitability in SHSY-5Y Neu...
Published 2019“…Somewhat surprisingly, the catalytically active form, methylated PP2A (mePP2A) was significantly decreased. In close correlation to these data, the phosphorylation state of two substrate proteins, sensitive to PP2A activity, GSK3β and Tau were found to be increased. …”
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A slow but steady nanoLuc: R162A mutation results in a decreased, but stable, nanoLuc activity
Published 2024“…Here, we combined molecular dynamics (MD) simulation and mutational analysis to show that the R162A mutation results in a decreased but stable <u>bioluminescence </u>activity of NLuc in living cells and in vitro. …”
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Decreased Interfacial Dynamics Caused by the N501Y Mutation in the SARS-CoV-2 S1 Spike:ACE2 Complex
Published 2022“…In this regard, the recent SARS-CoV-2 alpha, beta, and gamma variants (B.1.1.7, B.1.351, and P.1 lineages, respectively) are of great significance in that they contain several mutations that increase their transmission rates as evident from clinical reports. …”
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Kefir exhibits anti‑proliferative and pro‑apoptotic effects on colon adenocarcinoma cells with no significant effects on cell migration and invasion
Published 2014“…Results from RT‑PCR showed that kefir decreases the expression of transforming growth factor α (TGF‑α); and transforming growth factor‑β1 (TGF‑β1) in HT‑29 cells. …”
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Daucus carota pentane-based fractions arrest the cell cycle and increase apoptosis in MDA-MB-231 breast cancer cells
Published 2014“…The increase in apoptosis in response to treatment was also apparent in the increase in BAX and the decrease in Bcl-2 levels as well as the proteolytic cleavage of both caspase-3 and PARP as revealed by Western blot. …”
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The Role of Media Literacy in Countering Misinformation
Published 2023“…This thesis aims to examine the role of media literacy in combating misinformation and conspiracy theories related to COVID-19 vaccination. …”
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Bio fuel renewable energy, 3 rd generation bio fuel.
Published 2016“…Also, it will present the new technology of using algae and it significant role in sea pollution as many industries disposed of the chemical in the sea.…”
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A Feasibility Study for Solar Energy Generation Policy Mechanisms in The UAE
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RFX3 is essential for the generation of functional human pancreatic islets from stem cells
Published 2025“…<h3>Aims/hypothesis</h3><p dir="ltr">The role of regulatory factor X 3 (RFX3) in human pancreatic islet development has not been explored. …”
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Advancing Interpretability in Sequential Models Through Generative AI Rationalization Using GPT-4
Published 2025“…In this study, we investigate the role of Generative Pre-trained Transformer 4 (GPT-4) in enhancing interpretability of sequential predictions in Natural Language Processing (NLP). …”
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The role of soluble CD40L in autoimmune diseases
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Project Manager’s Role in Manage Project Knowledge Process: An Approach to Enhance Project Quality
Published 2023“…This paper highlights the significance of managing project knowledge from project initiation to completion, emphasizing the critical role of project managers in conducting lessons-learned sessions. …”
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The Role of School Leaders in Facilitating Continuous Professional Development to Empower Teachers in Private Schools in Dubai
Published 2022“…The outcomes of quantitative assessment by One-ANOVA analysis explicated that the leadership role had significant impacts on the professional empowerment of teachers through CPD implementation. …”
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