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Notch Signaling Inhibition by LY411575 Attenuates Osteoblast Differentiation and Decreased Ectopic Bone Formation Capacity of Human Skeletal (Mesenchymal) Stem Cells
Published 2019“…Among the tested molecules, LY411575, a potent γ-secretase and Notch signaling inhibitor, exhibited significant inhibitory effects on osteoblastic differentiation of hBMSCs manifested by reduced ALP activity, mineralized matrix formation, and decreased osteoblast-specific gene expression as well as in vivo ectopic bone formation. …”
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Pancreatitis is frequent among patients with side-branch intraductal papillary mucinous neoplasia diagnosed by EUS
Published 2009“…Side-branch (SB) IPMNs are thought to cause symptoms less frequently, and their association with pancreatitis is not well defined. …”
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A slow but steady nanoLuc: R162A mutation results in a decreased, but stable, nanoLuc activity
Published 2024“…In this regard, engineering of brighter bioluminescent proteins, i.e. luciferases, has played a significant role. This is acutely exemplified by the engineering of the NLuc <u>luciferase</u>, which is small in size and displays much enhanced bioluminescence and<u> thermal stability</u> compared to previously available luciferases. …”
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Effect of increasing the number of anchors on the flexural performance of FRP-strengthened RC beams
Published 2024“…The first beam was strengthened and unanchored, and the other two beams were strengthened and anchored with one or two 14-mm diameter FRP anchors on each side, respectively. Results showed that increasing the number of anchors significantly improved the flexural behavior of the strengthened beam in terms of the beam's response at failure and the strain utilized in the FRP laminates. …”
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Small molecule inhibition of stat3 enhances survival in mice with intracerebral melanoma
Published 2008Get full text
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Suppression of Unstable Flow by Using Rough Surfaces at Small Mass Flow Rates in a Radial Diffuser
Published 2006Get full text
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Optimizing the number of players and training bout durations in soccer small‐sided games: Effects on mood balance and technical performance
Published 2025“…Therefore, coaches should consider longer continuous bouts when planning SSGs‐based training to significantly decrease TMD and enhance technical‐tactical performance in soccer SSGs.…”
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Design and Testing of LCC-Compensated Dynamic Wireless Electric Vehicle Charging System
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Nonlinear Control of Brushless Dual-Fed Induction Generator With a Flywheel Energy Storage System for Improved System Performance
Published 2025“…After optimization, the SMC settling time was significantly reduced from 0.7 seconds to 19.97 milliseconds, achieving a 96.9% improvement in response speed, while its steady-state error decreased from 0.48 to 0.06, marking an 87.5% reduction in tracking error. …”
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YOLO-DefXpert: An Advanced Defect Detection on PCB Surfaces Using Improved YOLOv11 Algorithm
Published 2025“…Accurately identifying small defects on PCB surfaces remains a considerable challenge, particularly under complex background conditions, due to the intricate and compact layout of the boards. …”
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An Analysis of Thermal Comfort at the School Outdoor Spaces: A Case Study of the American School of Creative Science, Dubai, UAE
Published 2022“…Additionally, the addition of vegetation alone had an impact on the microclimate decreasing it by 5%. Thus, combining the strategies of vegetation, shade, green facades/roofs and small water features resulted in 5% to 25% reduction in PET depending on the corresponding location being analyzed. …”
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Acoustically activated release of estrone-targeted liposomes used for breast cancer treatment
Published 2016Get full text
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Innovation by Mergers and Acquisitions: Paradox of Acquired Organization’s Leadership Teams Commitment to Internal Innovation
Published 2013“…Especially, the influence the merger process has on the managers of the merging organizations with the significant increased size, diversification, behavioural procedural controls and increased use of leverage, all leading to the absorption of the managers time. …”
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An Investigative study to Explore Teachers` Attitude Towards the Inclusion of Learners on the Autism Spectrum Disorder and Learners with Meares Irlen Syndrome in Private Schools in...
Published 2019“…The data illustrated that there is a significant difference between teachers` prior knowledge of MIS and their awareness of its characteristics from one side and between their previous teaching experience from the other side. …”
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