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The Anti-Tumor Agent Sodium Selenate Decreases Methylated PP2A, Increases GSK3βY216 Phosphorylation, Including Tau Disease Epitopes and Reduces Neuronal Excitability in SHSY-5Y Neu...
Published 2019“…Somewhat surprisingly, the catalytically active form, methylated PP2A (mePP2A) was significantly decreased. In close correlation to these data, the phosphorylation state of two substrate proteins, sensitive to PP2A activity, GSK3β and Tau were found to be increased. …”
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Identifying and Assessing the Significance of Digital Twin Enablers in the Construction Industry
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Mapping subnational HIV mortality in six Latin American countries with incomplete vital registration systems
Published 2021“…Despite decreases in national HIV mortality in all countries—apart from Ecuador—across the period of study, we found broad variation in relative changes in HIV mortality at the municipality level and increasing relative inequality over time in all countries. …”
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A slow but steady nanoLuc: R162A mutation results in a decreased, but stable, nanoLuc activity
Published 2024“…Here, we combined molecular dynamics (MD) simulation and mutational analysis to show that the R162A mutation results in a decreased but stable <u>bioluminescence </u>activity of NLuc in living cells and in vitro. …”
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Decreased Interfacial Dynamics Caused by the N501Y Mutation in the SARS-CoV-2 S1 Spike:ACE2 Complex
Published 2022“…In this regard, the recent SARS-CoV-2 alpha, beta, and gamma variants (B.1.1.7, B.1.351, and P.1 lineages, respectively) are of great significance in that they contain several mutations that increase their transmission rates as evident from clinical reports. …”
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Ethnic and Gender Differences in Identifying Gifted Students
Published 2010“…The purpose of this study was to examine ethnic and gender differences in using DISCOVER, a performance-based assessment, for identifying gifted students. …”
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Kefir exhibits anti‑proliferative and pro‑apoptotic effects on colon adenocarcinoma cells with no significant effects on cell migration and invasion
Published 2014“…Results from RT‑PCR showed that kefir decreases the expression of transforming growth factor α (TGF‑α); and transforming growth factor‑β1 (TGF‑β1) in HT‑29 cells. …”
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Daucus carota pentane-based fractions arrest the cell cycle and increase apoptosis in MDA-MB-231 breast cancer cells
Published 2014“…The increase in apoptosis in response to treatment was also apparent in the increase in BAX and the decrease in Bcl-2 levels as well as the proteolytic cleavage of both caspase-3 and PARP as revealed by Western blot. …”
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Investigation of implementing STEM projects in a selective school in the United Arab Emirates
Published 2017“…The study will focus on six main factors: group formation, differentiation, achievement, motivation, assessment and to identify any gender differences. …”
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The Impact of Different Urban Configurations on Outdoor Thermal Comfort: A Case Study of the Military Camps in Abu Dhabi, UAE
Published 2016“…Phase One focused on identifying the most favourable urban configuration in terms of thermal behaviour out of six different proposals: existing linear blocks with a rectangular courtyard; proposed fortress blocks with a square courtyard; proposed fortress blocks with a rectangular courtyard; proposed U-shape blocks with a square courtyard; proposed L-shape blocks with a square courtyard; and proposed developed linear blocks with a rectangular courtyard. …”
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System biology approaches identified novel biomarkers and their signaling pathways involved in renal cell carcinoma with different human diseases
Published 2022“…The study also identified six prospective biomarkers, signaling pathways, and numerous critical regulatory and associated drug candidates for the disease. …”
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Invasive Plants Diversity, Ecological Status, and Distribution Pattern in Relation to Edaphic Factors in Different Habitat Types of District Mandi Bahauddin, Punjab, Pakistan
Published 2022“…Ordination analysis showed that different ecological factors had a significant (p ≤ 0.002) influence on vegetation. …”
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Association of single nucleotide polymorphisms with dyslipidemia and risk of metabolic disorders in the State of Qatar
Published 2023“…</p><h3>Results</h3><p dir="ltr">The genotypic frequencies of six SNPs were found to be significantly different in dyslipidemia patients subjects compared to the control group among males and females. …”
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