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A slow but steady nanoLuc: R162A mutation results in a decreased, but stable, nanoLuc activity
Published 2024“…In this regard, engineering of brighter bioluminescent proteins, i.e. luciferases, has played a significant role. …”
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R<sup>2</sup>S100K: Road-Region Segmentation Dataset for Semi-supervised Autonomous Driving in the Wild
Published 2024“…R<sup>2</sup>S100K comprises 100K images extracted from a large and diverse set of video sequences covering more than 1000 km of roadways. …”
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Decreased Interfacial Dynamics Caused by the N501Y Mutation in the SARS-CoV-2 S1 Spike:ACE2 Complex
Published 2022“…Additionally, we find that the N501Y mutant S1-RBD displays altered dynamics that likely aids in its enhanced interaction with ACE2. …”
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Notch Signaling Inhibition by LY411575 Attenuates Osteoblast Differentiation and Decreased Ectopic Bone Formation Capacity of Human Skeletal (Mesenchymal) Stem Cells
Published 2019“…Among the tested molecules, LY411575, a potent γ-secretase and Notch signaling inhibitor, exhibited significant inhibitory effects on osteoblastic differentiation of hBMSCs manifested by reduced ALP activity, mineralized matrix formation, and decreased osteoblast-specific gene expression as well as in vivo ectopic bone formation. …”
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Performance evaluation of 3D-printed PLA composites doped with WE43 magnesium alloy for bone tissue engineering applications
Published 2025“…While a low Mg content (5 %) only slightly impacted the print quality and dimensions, higher Mg concentrations (10 % and 15 %) led to increased weight, rougher surfaces, dimensional shrinkage in height, and overall poorer formation quality. Adding WE43 alloy to PLA decreased the average pore sizes of the composites. …”
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Indomethacin as a Rescue Therapy for Patent Ductus Arteriosus in Extremely Premature Infants after Failed Ibuprofen Treatment
Published 2023“…While most PDAs close after one 3-day course of either medicine, a repeat course may be necessary before considering surgical ligation for those who remain with hsPDAs. In our practice, we administer one or two courses of ibuprofen followed by a single course of indomethacin if the PDA has not shown closure or decrease in size on the echocardiogram (echo) exam. …”
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The Anti-Tumor Agent Sodium Selenate Decreases Methylated PP2A, Increases GSK3βY216 Phosphorylation, Including Tau Disease Epitopes and Reduces Neuronal Excitability in SHSY-5Y Neu...
Published 2019“…Somewhat surprisingly, the catalytically active form, methylated PP2A (mePP2A) was significantly decreased. In close correlation to these data, the phosphorylation state of two substrate proteins, sensitive to PP2A activity, GSK3β and Tau were found to be increased. …”
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Effects of support on Ni-based catalysts for dry reforming of methane
Published 2025“…The absence of δ-NiO species in the La<sub>2</sub>O<sub>3</sub> crystals suggests that Ni<sup>2+</sup> did not induce inside the lattice. …”
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Design and Development of Inexpensive Paper-Based Chemosensors for Detection of Divalent Copper
Published 2023“…The easy preparation and high stability of dye solutions, easy functionalization of the paper-based sensors, high selectivity over other cations, low interference of counter anion, and significantly low detection limit of 2.23 ppm make it an effective Cu<sup>2+</sup> ion sensor for real-time application in near future.…”
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Comparative life-cycle assessment of reverse osmosis and microalgae-based treatment for hypersaline oilfield produced water
Published 2025“…<p dir="ltr">The management of hypersaline produced water (130–190 g L<sup>−1</sup> TDS) from oil and gas operations—especially in regions with carbon-intensive grids like Kuwait—poses significant environmental and operational challenges. …”
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Silver-based dressings for the prevention of surgical site infections: evidence from randomized trials
Published 2025“…Heterogeneity was moderate (<i>I</i><sup><em>2</em></sup>=53%). </p><h3>Conclusions</h3><p dir="ltr">Silver-based dressings reduce the risk of SSIs significantly; however, further high-quality RCTs are needed to confirm their benefits across different surgical contexts and patient populations.…”
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Hyperspectral-physiological based predictive model for transpiration in greenhouses under CO<sub>2</sub> enrichment
Published 2023“…The XGBoost model outperformed the DNN and SVR models with higher R<sup>2</sup> of 0.62 – 7.53%, lower RMSE and MAE values of 9.74 – 46.19 mmol/m<sup>2</sup>.s and 13.74 – 39.08 mmol/m<sup>2</sup>.s respectively with microclimate, physiological and hyperspectral based vegetation index inputs. …”