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A slow but steady nanoLuc: R162A mutation results in a decreased, but stable, nanoLuc activity
Published 2024“…Here, we combined molecular dynamics (MD) simulation and mutational analysis to show that the R162A mutation results in a decreased but stable <u>bioluminescence </u>activity of NLuc in living cells and in vitro. …”
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Accelerating the Design of Photocatalytic Surfaces for Antimicrobial Application: Machine Learning Based on a Sparse Dataset
Published 2021“…This machine-learning-assisted strategy offers the opportunity to reduce the cost, labor, time, and precursors consumed during experiments that are based on trial and error. Our strategy may significantly accelerate the large-scale deployment of photocatalysts as a promising route to mitigate fomite transmission of pathogens (bacteria, viruses, fungi) in hospital settings and public places.…”
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The Anti-Tumor Agent Sodium Selenate Decreases Methylated PP2A, Increases GSK3βY216 Phosphorylation, Including Tau Disease Epitopes and Reduces Neuronal Excitability in SHSY-5Y Neu...
Published 2019“…Somewhat surprisingly, the catalytically active form, methylated PP2A (mePP2A) was significantly decreased. In close correlation to these data, the phosphorylation state of two substrate proteins, sensitive to PP2A activity, GSK3β and Tau were found to be increased. …”
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Destabilization of stable bentonite colloidal suspension using choline chloride based deep eutectic solvent: Optimization study
Published 2021“…<p dir="ltr">holine chloride (ChCl) based natural deep eutectic solvents (NADES) were synthesized and tested as coagulant for stable bentonite colloidal suspensions. …”
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Exploration and analysis of On-Surface and In-Air handwriting attributes to improve dysgraphia disorder diagnosis in children based on machine learning methods
Published 2023“…The proposed work analyzes the various attributes of online handwritten data recorded by digitizing tablets during On-Surface (when the pen is on the tablet’s surface) and In-Air activity (when the pen is away from the tablet’s surface). …”
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Exploration and analysis of On-Surface and In-Air handwriting attributes to improve dysgraphia disorder diagnosis in children based on machine learning methods
Published 2023“…The proposed work analyzes the various attributes of online handwritten data recorded by digitizing tablets during On-Surface (when the pen is on the tablet’s surface) and In-Air activity (when the pen is away from the tablet’s surface). …”
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Synthesis of graphene oxide nanofluid based micro-nano scale surfaces for high-performance nucleate boiling thermal management systems
Published 2021“…In comparison, M surface-based thermal management system resulted in the highest efficiency.…”
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Active laminar mixing induced by surface disturbance
Published 2006“…Moreover, these actuators are water-based, eliminating the need for coating or electrical isolation. …”
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Decreased Interfacial Dynamics Caused by the N501Y Mutation in the SARS-CoV-2 S1 Spike:ACE2 Complex
Published 2022“…<p dir="ltr">Coronavirus Disease of 2019 (COVID-19) caused by Severe Acute Respiratory Syndrome Coronavirus 2 (SARS-CoV-2) has resulted in a massive health crisis across the globe, with some genetic variants gaining enhanced infectivity and competitive fitness, and thus significantly aggravating the global health concern. …”
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Deep learning-based modeling of land use/land cover changes impact on land surface temperature in Greater Amman Municipality, Jordan (1980–2030)
Published 2024“…</p><h2>Other Information</h2><p dir="ltr">Published in: GeoJournal<br>License: <a href="https://creativecommons.org/licenses/by/4.0" target="_blank">https://creativecommons.org/licenses/by/4.0</a><br>See article on publisher's website: <a href="https://dx.doi.org/10.1007/s10708-024-11187-3" target="_blank">https://dx.doi.org/10.1007/s10708-024-11187-3</a></p>…”
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Notch Signaling Inhibition by LY411575 Attenuates Osteoblast Differentiation and Decreased Ectopic Bone Formation Capacity of Human Skeletal (Mesenchymal) Stem Cells
Published 2019“…Among the tested molecules, LY411575, a potent γ-secretase and Notch signaling inhibitor, exhibited significant inhibitory effects on osteoblastic differentiation of hBMSCs manifested by reduced ALP activity, mineralized matrix formation, and decreased osteoblast-specific gene expression as well as in vivo ectopic bone formation. …”
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Indomethacin as a Rescue Therapy for Patent Ductus Arteriosus in Extremely Premature Infants after Failed Ibuprofen Treatment
Published 2023“…<p dir="ltr">Hemodynamically significant patent ductus arteriosus (hsPDA) is a major cause of neonatal morbidity and mortality in extremely low birth weight (ELBW) infants. …”
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Kefir exhibits anti‑proliferative and pro‑apoptotic effects on colon adenocarcinoma cells with no significant effects on cell migration and invasion
Published 2014“…Our data suggest that kefir is able to inhibit the proliferation and induce apoptosis in HT‑29 and Caco‑2 CRC cells, yet it does not exhibit a significant effect on the motility and invasion of these cells in vitro.…”
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Fermentation-induced modifications to the structural, surface, and functional properties of quinoa proteins
Published 2025“…Furthermore, surface properties undergo modifications, with a decrease in surface charge from −32.82 to −39.63 and a reduction in surface hydrophobicity from 580 to 382 a.u. …”
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