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target based » agent based (Expand Search), bret based (Expand Search)
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target based » agent based (Expand Search), bret based (Expand Search)
genes » genres (Expand Search), gene (Expand Search)
decrease » increase (Expand Search)
greatest » greater (Expand Search)
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1
Exploring the Significance of Publication-Age-Based Parameters for Evaluating Researcher Impact
Published 2023“…</p><h2>Other Information</h2><p dir="ltr">Published in: IEEE Access<br>License: <a href="https://creativecommons.org/licenses/by/4.0/" target="_blank">https://creativecommons.org/licenses/by/4.0/</a><br>See article on publisher's website: <a href="https://dx.doi.org/10.1109/access.2023.3304013" target="_blank">https://dx.doi.org/10.1109/access.2023.3304013</a></p>…”
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2
Treating Cancers Using Nature’s Medicine: Significance and Challenges
Published 2021“…In recent decades, the emphasis on identifying therapeutic plant-based active principles led to significant advancements in the identification and use of natural compounds to treat various diseases (Figure 1) [2,3]. …”
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Detection of statistically significant network changes in complex biological networks
Published 2017“…</p><h3>Methods</h3><p dir="ltr">In this paper, we propose an improvement over the state-of-the-art based on the Generalized Hamming Distance adopted for evaluating the topological difference between two networks and estimating its statistical significance. …”
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Significance of Avicennia Marina in the Arabian Gulf Environment: A Review
Published 2025“…This review addresses the current knowledge gap by providing an overview of Avicennia marina distribution in the Gulf, exploring the significance of its ecosystem services, analyzing the impacts of stressors, and examining conservation and restoration efforts, with attention to nature-based and biotechnological approaches for promoting mangrove growth and conservation in the Gulf.…”
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Targeting acute myeloid leukemia cells with novel photosensitive ruthenium-based metal-organic compounds. (c2015)
Published 2016“…In this study, we aim to establish a ruthenium-based model for effectively targeting AML, with the goal of later developing approaches to selectively target AML with complexes based on this model. …”
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Nanoparticle enrichment mass-spectrometry proteomics identifies protein-altering variants for precise pQTL mapping
Published 2024“…</i>) where we quantify over 18,000 unique peptides from nearly 3000 proteins in more than 320 blood samples from a multi-ethnic cohort in a bottom-up, peptide-centric, mass spectrometry-based proteomics approach. We identify 184 protein-altering variants in 137 genes that are significantly associated with their corresponding variant peptides, confirming target specificity of co-associated affinity binders, identifying putatively causal cis-encoded proteins and providing experimental evidence for their presence in blood, including proteins that may be inaccessible to affinity-based proteomics.…”
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pH and ultrasound dual-responsive drug delivery system based on PEG–folate-functionalized Iron-based metal–organic framework for targeted doxorubicin delivery
Published 2021“…The folate moiety is used to specifically target several cancers overexpressing the folate receptor (FR). …”
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A New Restriction Endonuclease-Based Method for Highly-Specific Detection of DNA Targets from Methicillin-Resistant Staphylococcus aureus
Published 2014“…We developed a new approach for analysis of PCR amplicons based on restriction endonuclease digestion. The first stage of the restriction enzyme assay is hybridization of a target DNA to immobilized complementary oligonucleotide probes that carry a molecular marker, horseradish peroxidase (HRP). …”
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A Novel Steganography Technique for Digital Images Using the Least Significant Bit Substitution Method
Published 2022“…Therefore, the proposed work, in this paper, is based on the Least Significant Bit (LSB) substitution method. …”
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A slow but steady nanoLuc: R162A mutation results in a decreased, but stable, nanoLuc activity
Published 2024“…<p dir="ltr">NanoLuc (NLuc) <u>luciferase</u> has found extensive application in designing a range of <u>biologica</u><u>l</u><u> assays,</u> including <u>gene expression analysis</u>, protein-protein interaction, and protein conformational changes due to its enhanced brightness and small size. …”
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Deep random vector functional link transformer network with multiple output layers for significant wave height forecasting
Published 2025“…This paper introduces a novel random vector functional link transformer (RFT) and ensemble deep random vector functional link transformer (edRFT) networks to capture the dynamic characteristics of significant wave heights. The model employs hidden blocks based on transformer encoders to effectively capture complex sequential dependencies in the data. …”
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Protecting Private Attributes in App Based Mobile User Profiling
Published 2020“…<p dir="ltr">The Analytics companies enable successful targeted advertising via user profiles, derived from the mobile apps installed by specific users, and hence have become an integral part of the mobile advertising industry. …”
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Notch Signaling Inhibition by LY411575 Attenuates Osteoblast Differentiation and Decreased Ectopic Bone Formation Capacity of Human Skeletal (Mesenchymal) Stem Cells
Published 2019“…Among the tested molecules, LY411575, a potent γ-secretase and Notch signaling inhibitor, exhibited significant inhibitory effects on osteoblastic differentiation of hBMSCs manifested by reduced ALP activity, mineralized matrix formation, and decreased osteoblast-specific gene expression as well as in vivo ectopic bone formation. …”
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Kefir exhibits anti‑proliferative and pro‑apoptotic effects on colon adenocarcinoma cells with no significant effects on cell migration and invasion
Published 2014“…The expression of certain genes involved in proliferation and apoptosis was measured using reverse transcriptase‑polymerase chain reaction (RT‑PCR) and western blotting. …”
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Impact of inflammation, gene variants, and cigarette smoking on coronary artery disease risk
Published 2015“…Moreover, a significant smoking-gene interaction is determined with CYP1A1 MspI polymorphism rs4646903 and is associated with a decreased risk of CAD in current smokers (OR 0.52137). …”
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Genetic Variation in CCL5 Signaling Genes and Triple Negative Breast Cancer: Susceptibility and Prognosis Implications
Published 2019“…We found a highly significant association between the <b><i>CCND1</i></b><b> </b><b>rs614367-TT</b> genotype (OR = 5.14; <i>P</i> = 0.004) and TNBC risk, and identified a significant association between the <b>rs614367-T</b> allele and decreased PFS in TNBC. …”
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Personality traits as predictors of vulnerability to persuasion in social engineering amongst risk-aware targets
Published 2025“…Additionally, we found no significant differences in vulnerability between the Arab and UK samples. …”