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Showing 1 - 20 results of 1,692 for search '(( significant target based ) OR ( significant ((mean decrease) OR (a decrease)) ))', query time: 0.12s Refine Results
  1. 1

    Exploring the Significance of Publication-Age-Based Parameters for Evaluating Researcher Impact by Ghulam Mustafa (458105)

    Published 2023
    “…</p><h2>Other Information</h2><p dir="ltr">Published in: IEEE Access<br>License: <a href="https://creativecommons.org/licenses/by/4.0/" target="_blank">https://creativecommons.org/licenses/by/4.0/</a><br>See article on publisher's website: <a href="https://dx.doi.org/10.1109/access.2023.3304013" target="_blank">https://dx.doi.org/10.1109/access.2023.3304013</a></p>…”
  2. 2

    A slow but steady nanoLuc: R162A mutation results in a decreased, but stable, nanoLuc activity by Wesam S. Ahmed (10170053)

    Published 2024
    “…Here, we combined molecular dynamics (MD) simulation and mutational analysis to show that the R162A mutation results in a decreased but stable <u>bioluminescence </u>activity of NLuc in living cells and in vitro. …”
  3. 3

    Treating Cancers Using Nature’s Medicine: Significance and Challenges by Samson Samuel (6828956)

    Published 2021
    “…In recent decades, the emphasis on identifying therapeutic plant-based active principles led to significant advancements in the identification and use of natural compounds to treat various diseases (Figure 1) [2,3]. …”
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    Detection of statistically significant network changes in complex biological networks by Raghvendra Mall (581171)

    Published 2017
    “…</p><h3>Methods</h3><p dir="ltr">In this paper, we propose an improvement over the state-of-the-art based on the Generalized Hamming Distance adopted for evaluating the topological difference between two networks and estimating its statistical significance. …”
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    Significance of Avicennia Marina in the Arabian Gulf Environment: A Review by Kaiprath Puthiyapurayil Haseeba (21392966)

    Published 2025
    “…This review addresses the current knowledge gap by providing an overview of Avicennia marina distribution in the Gulf, exploring the significance of its ecosystem services, analyzing the impacts of stressors, and examining conservation and restoration efforts, with attention to nature-based and biotechnological approaches for promoting mangrove growth and conservation in the Gulf.…”
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    The Anti-Tumor Agent Sodium Selenate Decreases Methylated PP2A, Increases GSK3βY216 Phosphorylation, Including Tau Disease Epitopes and Reduces Neuronal Excitability in SHSY-5Y Neu... by Wesal Habbab (17346961)

    Published 2019
    “…Somewhat surprisingly, the catalytically active form, methylated PP2A (mePP2A) was significantly decreased. In close correlation to these data, the phosphorylation state of two substrate proteins, sensitive to PP2A activity, GSK3β and Tau were found to be increased. …”
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    Targeting acute myeloid leukemia cells with novel photosensitive ruthenium-based metal-organic compounds. (c2015) by Azar, Daniel Fadi

    Published 2016
    “…In this study, we aim to establish a ruthenium-based model for effectively targeting AML, with the goal of later developing approaches to selectively target AML with complexes based on this model. …”
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    masterThesis
  12. 12

    Nanoparticle enrichment mass-spectrometry proteomics identifies protein-altering variants for precise pQTL mapping by Karsten Suhre (67967)

    Published 2024
    “…</i>) where we quantify over 18,000 unique peptides from nearly 3000 proteins in more than 320 blood samples from a multi-ethnic cohort in a bottom-up, peptide-centric, mass spectrometry-based proteomics approach. We identify 184 protein-altering variants in 137 genes that are significantly associated with their corresponding variant peptides, confirming target specificity of co-associated affinity binders, identifying putatively causal cis-encoded proteins and providing experimental evidence for their presence in blood, including proteins that may be inaccessible to affinity-based proteomics.…”
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    pH and ultrasound dual-responsive drug delivery system based on PEG–folate-functionalized Iron-based metal–organic framework for targeted doxorubicin delivery by Ahmed, Ahmed H.S

    Published 2021
    “…The folate moiety is used to specifically target several cancers overexpressing the folate receptor (FR). …”
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    article
  14. 14

    A New Restriction Endonuclease-Based Method for Highly-Specific Detection of DNA Targets from Methicillin-Resistant Staphylococcus aureus by Maria W. Smith (18807382)

    Published 2014
    “…We developed a new approach for analysis of PCR amplicons based on restriction endonuclease digestion. The first stage of the restriction enzyme assay is hybridization of a target DNA to immobilized complementary oligonucleotide probes that carry a molecular marker, horseradish peroxidase (HRP). …”
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    A Novel Steganography Technique for Digital Images Using the Least Significant Bit Substitution Method by Shahid Rahman (16904613)

    Published 2022
    “…Therefore, the proposed work, in this paper, is based on the Least Significant Bit (LSB) substitution method. …”
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    Decreased Interfacial Dynamics Caused by the N501Y Mutation in the SARS-CoV-2 S1 Spike:ACE2 Complex by Wesam S. Ahmed (10170053)

    Published 2022
    “…<p dir="ltr">Coronavirus Disease of 2019 (COVID-19) caused by Severe Acute Respiratory Syndrome Coronavirus 2 (SARS-CoV-2) has resulted in a massive health crisis across the globe, with some genetic variants gaining enhanced infectivity and competitive fitness, and thus significantly aggravating the global health concern. …”
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    Deep random vector functional link transformer network with multiple output layers for significant wave height forecasting by Aryan Bhambu (18767731)

    Published 2025
    “…This paper introduces a novel random vector functional link transformer (RFT) and ensemble deep random vector functional link transformer (edRFT) networks to capture the dynamic characteristics of significant wave heights. The model employs hidden blocks based on transformer encoders to effectively capture complex sequential dependencies in the data. …”
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    Protecting Private Attributes in App Based Mobile User Profiling by Imdad Ullah (18372291)

    Published 2020
    “…<p dir="ltr">The Analytics companies enable successful targeted advertising via user profiles, derived from the mobile apps installed by specific users, and hence have become an integral part of the mobile advertising industry. …”
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