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A slow but steady nanoLuc: R162A mutation results in a decreased, but stable, nanoLuc activity
Published 2024“…Here, we combined molecular dynamics (MD) simulation and mutational analysis to show that the R162A mutation results in a decreased but stable <u>bioluminescence </u>activity of NLuc in living cells and in vitro. …”
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The Impact of Transformational Verses Strategic Leadership Styles in the Success of Engineering Teams
Published 2023“…Engineering teams' success is based on their ability to work effectively and use their skills, experience, and knowledge to achieve results. …”
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The Anti-Tumor Agent Sodium Selenate Decreases Methylated PP2A, Increases GSK3βY216 Phosphorylation, Including Tau Disease Epitopes and Reduces Neuronal Excitability in SHSY-5Y Neu...
Published 2019“…Somewhat surprisingly, the catalytically active form, methylated PP2A (mePP2A) was significantly decreased. In close correlation to these data, the phosphorylation state of two substrate proteins, sensitive to PP2A activity, GSK3β and Tau were found to be increased. …”
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Culture Diversity Impacts on Teams Performance and Innovation Role in Dubai Private Sector
Published 2012“…Cultural diversity is having a significant impact on organizations at the current time. …”
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Innovation by Mergers and Acquisitions: Paradox of Acquired Organization’s Leadership Teams Commitment to Internal Innovation
Published 2013“…This dissertation highlights the trade off between growth via M&A and executive leadership team commitment to internal innovation (R&D). It is based on the results gathered from the employees of organizations XYZ and ABC which has combined to form a resultant entity DRC, part of a conglomerate called AIMI. …”
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The Influence of Kanban Project Management Methodology Success Factors on Data Science Project Teams
Published 2022“…The results of the study were based on the collection of survey data from the target population of project managers and other members of the Data Science project teams. …”
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Internet Searches for Medical Symptoms Before Seeking Information on 12-Step Addiction Treatment Programs: A Web-Search Log Analysis
Published 2019“…Specifically, symptom queries were first determined to be significantly predictive of subsequent 12-step queries if the probability of querying a medical symptom by those who later sought information about the 12-step program exceeded the probability of that same query being made by a comparison group of all other Bing users in the United States. …”
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Decreased Interfacial Dynamics Caused by the N501Y Mutation in the SARS-CoV-2 S1 Spike:ACE2 Complex
Published 2022“…<p dir="ltr">Coronavirus Disease of 2019 (COVID-19) caused by Severe Acute Respiratory Syndrome Coronavirus 2 (SARS-CoV-2) has resulted in a massive health crisis across the globe, with some genetic variants gaining enhanced infectivity and competitive fitness, and thus significantly aggravating the global health concern. …”
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Indomethacin as a Rescue Therapy for Patent Ductus Arteriosus in Extremely Premature Infants after Failed Ibuprofen Treatment
Published 2023“…<p dir="ltr">Hemodynamically significant patent ductus arteriosus (hsPDA) is a major cause of neonatal morbidity and mortality in extremely low birth weight (ELBW) infants. …”
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Notch Signaling Inhibition by LY411575 Attenuates Osteoblast Differentiation and Decreased Ectopic Bone Formation Capacity of Human Skeletal (Mesenchymal) Stem Cells
Published 2019“…Among the tested molecules, LY411575, a potent γ-secretase and Notch signaling inhibitor, exhibited significant inhibitory effects on osteoblastic differentiation of hBMSCs manifested by reduced ALP activity, mineralized matrix formation, and decreased osteoblast-specific gene expression as well as in vivo ectopic bone formation. …”
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The Impact of School Senior Leadership Team (SLT) Emotional Intelligence on Teachers’ Professional Development Programs and School Performance in the UAE
Published 2020“…Results revealed that school leadership team emotional intelligence has a significant effect on teachers’ professional development; this is true for the interpersonal relationship (β = .367, p < 0.01), and the ability of school leadership team to adapt to situations based on existing demands (β = .224, p < 0.01). …”
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Kefir exhibits anti‑proliferative and pro‑apoptotic effects on colon adenocarcinoma cells with no significant effects on cell migration and invasion
Published 2014“…Our data suggest that kefir is able to inhibit the proliferation and induce apoptosis in HT‑29 and Caco‑2 CRC cells, yet it does not exhibit a significant effect on the motility and invasion of these cells in vitro.…”
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Emotional Intelligence in Leaders: A Case study of its effect on Team performance in the construction industry of Dubai, U.A.E
Published 2009“…The purpose of this study is to qualitatively examine the relationship between emotional intelligence of leaders on team performance, based on the Emotional Intelligence Inventory test (ECI) of Hay Group. …”
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Optimizing the number of players and training bout durations in soccer small‐sided games: Effects on mood balance and technical performance
Published 2025“…</p><h3>Results</h3><p dir="ltr">The data demonstrated that the continuous‐bout‐duration (1 × 12 min) of 4vs4 and 3vs3 SSGs was characterized by a significant decrease in total mood disturbance (TMD) compared to 2 × 6 min and 3 × 4 min (4vs4:<i>p</i> < 0.01; 3vs3:<i>p</i> < 0.001). …”
