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The Anti-Tumor Agent Sodium Selenate Decreases Methylated PP2A, Increases GSK3βY216 Phosphorylation, Including Tau Disease Epitopes and Reduces Neuronal Excitability in SHSY-5Y Neu...
Published 2019“…Somewhat surprisingly, the catalytically active form, methylated PP2A (mePP2A) was significantly decreased. In close correlation to these data, the phosphorylation state of two substrate proteins, sensitive to PP2A activity, GSK3β and Tau were found to be increased. …”
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A novel hybrid photovoltaic/thermal-fuel cell system for efficient hydrogen, heat, and power generation: Techno-economic and environmental evaluation
Published 2025“…Furthermore, increasing fuel cell temperature from 40 °C to 100 °C significantly improves overall η<sub>PVT-FC</sub> and m<sub>PVT-FC</sub>, demonstrating the direct impact of thermal regulation on system performance. …”
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Double diffusive mixed convection and entropy generation analysis of NEPCM-water mixture in a π-shaped cavity
Published 2025“…Entropy generation analysis reveals that thermal irreversibilities dominate, with both magnetic field strength and NEPCM concentration reducing system irreversibilities. …”
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Thermal challenges in lithium-ion battery technology: Investigating performance and thermal stability
Published 2025“…Elevated temperatures exacerbate internal resistance and accelerate chemical reactions within the battery, leading to heat generation, performance loss, and potential safety risks, including thermal runaway. …”
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A slow but steady nanoLuc: R162A mutation results in a decreased, but stable, nanoLuc activity
Published 2024“…Here, we combined molecular dynamics (MD) simulation and mutational analysis to show that the R162A mutation results in a decreased but stable <u>bioluminescence </u>activity of NLuc in living cells and in vitro. …”
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Decreased Interfacial Dynamics Caused by the N501Y Mutation in the SARS-CoV-2 S1 Spike:ACE2 Complex
Published 2022“…In this regard, the recent SARS-CoV-2 alpha, beta, and gamma variants (B.1.1.7, B.1.351, and P.1 lineages, respectively) are of great significance in that they contain several mutations that increase their transmission rates as evident from clinical reports. …”
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Kefir exhibits anti‑proliferative and pro‑apoptotic effects on colon adenocarcinoma cells with no significant effects on cell migration and invasion
Published 2014“…Results from RT‑PCR showed that kefir decreases the expression of transforming growth factor α (TGF‑α); and transforming growth factor‑β1 (TGF‑β1) in HT‑29 cells. …”
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Numerical Modeling of Nanoparticle-Assisted Laser Thermal Ablation of Tumors
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On the spreading of non-canonical thermals from direct numerical simulations
Published 2020“…These differences persist over a significant period of time and help generate a cross-flow component that is otherwise not present in canonical cases. …”
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Daucus carota pentane-based fractions arrest the cell cycle and increase apoptosis in MDA-MB-231 breast cancer cells
Published 2014“…The increase in apoptosis in response to treatment was also apparent in the increase in BAX and the decrease in Bcl-2 levels as well as the proteolytic cleavage of both caspase-3 and PARP as revealed by Western blot. …”
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Assessing the potential of network reconfiguration to improve distributed generation hosting capacity in active distribution systems
Published 2014“…As the amount of distributed generation (DG) is growing worldwide, the need to increase the hosting capacity of distribution systems without reinforcements is becoming nowadays a major concern. …”
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Study on adaptive thermal comfort model and behavioral adaptation in naturally ventilated residential buildings, Jimma Town, Ethiopia
Published 2023“…This study aimed to investigate comfort temperature, adaptive models, and behavioral adaptations in naturally ventilated residential buildings in Jimma town, Ethiopia. Our thermal comfort field survey involved 870 occupants from 104 houses, generating 5220 datasets between February and September 2020. …”
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