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A slow but steady nanoLuc: R162A mutation results in a decreased, but stable, nanoLuc activity
Published 2024“…In this regard, engineering of brighter bioluminescent proteins, i.e. luciferases, has played a significant role. …”
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Deep random vector functional link transformer network with multiple output layers for significant wave height forecasting
Published 2025“…The computational results demonstrate the superiority of the proposed models through a comparative analysis against state-of-the-art approaches across fifteen significant wave height time series, validated by three error metrics and a statistical test.…”
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Treating Cancers Using Nature’s Medicine: Significance and Challenges
Published 2021“…In recent decades, the emphasis on identifying therapeutic plant-based active principles led to significant advancements in the identification and use of natural compounds to treat various diseases (Figure 1) [2,3]. …”
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Detection of statistically significant network changes in complex biological networks
Published 2017“…The proposed procedure exploits a more effective model selection criteria to generate <i>p</i>-values for statistical significance and is more efficient in terms of computational time and prediction accuracy than literature methods. …”
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W-Transformers : A Wavelet-based Transformer Framework for Univariate Time Series Forecasting
Published 2022“…We present a novel framework for univariate time series representation learning based on the wavelet-based transformer encoder architecture and call it W-Transformer. …”
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Special Issue: Empowering eHealth with Smart Internet of Things (IoT) Medical Devices
Published 2019“…IoT helps to store data for millions of patients and perform analysis in real-time, promoting an evidence-based medicine system. …”
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Decreased Interfacial Dynamics Caused by the N501Y Mutation in the SARS-CoV-2 S1 Spike:ACE2 Complex
Published 2022“…Additionally, we find that the N501Y mutant S1-RBD displays altered dynamics that likely aids in its enhanced interaction with ACE2. …”
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Non-Linear Time History Analysis of Moment Frame Structure with Performance-Based Approach on Different Concrete Compressive Strengths
Published 2023“…Keywords: Performance Based Design, PBD, Perform3D, time history analysis, pushover analysis, nonlinear concrete, concrete compressive strength…”
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Notch Signaling Inhibition by LY411575 Attenuates Osteoblast Differentiation and Decreased Ectopic Bone Formation Capacity of Human Skeletal (Mesenchymal) Stem Cells
Published 2019“…Among the tested molecules, LY411575, a potent γ-secretase and Notch signaling inhibitor, exhibited significant inhibitory effects on osteoblastic differentiation of hBMSCs manifested by reduced ALP activity, mineralized matrix formation, and decreased osteoblast-specific gene expression as well as in vivo ectopic bone formation. …”
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Performance evaluation of 3D-printed PLA composites doped with WE43 magnesium alloy for bone tissue engineering applications
Published 2025“…While a low Mg content (5 %) only slightly impacted the print quality and dimensions, higher Mg concentrations (10 % and 15 %) led to increased weight, rougher surfaces, dimensional shrinkage in height, and overall poorer formation quality. Adding WE43 alloy to PLA decreased the average pore sizes of the composites. …”
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GIS-BIM Based Regional Seismic Risk Assessment for Dubai, UAE
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Time to diagnose and time to surgery in patients presenting with necrotizing fasciitis: a retrospective analysis
Published 2025“…While early surgical intervention is vital, our findings suggest that the time to diagnosis and subsequent resuscitation efforts may significantly impact survival. …”
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Kefir exhibits anti‑proliferative and pro‑apoptotic effects on colon adenocarcinoma cells with no significant effects on cell migration and invasion
Published 2014“…To assess the effect of kefir on cancer metastasis, wound‑healing and time‑lapse movies, in addition to collagen‑based invasion assay, were used. …”
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