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High-amylose carboxymethyl starch matrices for oral sustained drug-release
Published 2016“…High-amylose sodium carboxymethyl starch (HASCA) is an interesting excipient for sustained drug-release in solid oral dosage forms. In addition to the easy manufacture of tablets by direct compression, the results show that in vitro drug-release from an optimized HASCA formulation is not affected by either acidic pH value or acidic medium residence time. …”
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Propagation and deposition of non-circular finite release particle-laden currents
Published 2015“…The dynamics of non-axisymmetric turbidity currents is considered here for a range of Reynolds numbers of O (104) when based on the initial height of the release. The study comprises a series of experiments and highly resolved simulations for which a finite volume of particle-laden solution is released into fresh water. …”
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A slow but steady nanoLuc: R162A mutation results in a decreased, but stable, nanoLuc activity
Published 2024“…Here, we combined molecular dynamics (MD) simulation and mutational analysis to show that the R162A mutation results in a decreased but stable <u>bioluminescence </u>activity of NLuc in living cells and in vitro. …”
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Kinetics of acoustic release of doxorubicin from stabilized and unstabilized micelles and the effect of temperature
Published 2011“…Kinetic models were used to regress release and re-encapsulation time constants for three different compounds, namely non-stabilizedռ Pluronic® P105 micelles, P105 micelles stabilized using an interpenetrating network of N,N-diethylacrylamide and micelles formed by PEO-b-poly(NIPAAm-co-HEMA-lactate ռ). …”
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A receptor-centric decision support system for the mitigation of nuclear power atmospheric release incidents
Published 2023“…This framework, which utilizes time-dependent source terms and the JRODOS system, is exemplified within a region home to multiple nuclear plants. …”
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Nomograph derivation for underwater sour gas releases in shallow waters based on computational fluid dynamics simulations
Published 2024“…<p dir="ltr">Ruptured <u>underwater pipelines</u> releasing sour gas (i.e., natural gas with high concentrations of H<sub>2</sub>S) pose significant threats to environmental safety due to their toxic and contaminative properties. …”
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Degradation kinetics of stabilized Pluronic micelles under the action of ultrasound
Published 2009“…Results show that ultrasound does disrupt the covalent network of the stabilized micelles, but the time constant of network degradation is very long compared to the time constant pertaining to drug release from micelles. …”
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Epidemiological and clinical characteristics of fall-related injuries: a retrospective study
Published 2020“…</p> <h2>Conclusion</h2> <p>Fall-related injuries remain as significant burden even in a level 1 trauma center. …”
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Increased Frequency of Severe Hypoglycemia with the Modified-Release Gliclazide Compared to Glimepiride in Diabetic Older Adults; Propensity Score-Adjusted Analysis
Published 2022“…The risk of SHEA (Adjusted Odds Ratio AOR 6.74, p=0.002), falls (AOR 1.43, p=0.003), fractures (AOR 1.43, p=0.01), CVEA (AOR 1.66, p< 0.001), recurrent ED admission (AOR 1.39, p=0.002) were significantly higher. At the same time, documented hypoglycemia was insignificantly higher (AOR 1.17, p= 0.444) with gliclazide MR compared to glimepiride. …”
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Hyper-Hypo study: A Retrospective Observational Study of Neonatal Hypoglycemia Related to Maternal Hypertension
Published 2023“…On the other hand, neonates of hypertensive mothers administered with methyldopa showed a significant decrease of initial blood glucose reading.…”
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Application of hierarchical oligonucleotide primer extension (HOPE) to assess relative abundances of ammonia- and nitrite-oxidizing bacteria
Published 2017“…There was a corresponding significant decrease in the relative abundance of NOB, specifically Nitrospira and those affiliated to comammox, during the shock loading. …”
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A Sociodemographic Analysis of the Impact of COVID-19-Related Schools’ Closure on the Diet and Physical Activity of Children and Adolescents in Qatar
Published 2023“…Higher parental educational levels, maternal employment, and having a positive family history of obesity and/or overweight in first-degree relatives were significantly associated with adverse lifestyle changes during schools’ closure.…”
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Spatial, temporal, and demographic patterns in prevalence of smoking tobacco use and attributable disease burden in 204 countries and territories, 1990–2019: a systematic analysis...
Published 2021“…Although prevalence of smoking had decreased significantly since 1990 among both males (27·5% [26·5–28·5] reduction) and females (37·7% [35·4–39·9] reduction) aged 15 years and older, population growth has led to a significant increase in the total number of smokers from 0·99 billion (0·98–1·00) in 1990. …”
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Mutations in L-type amino acid transporter-2 support SLC7A8 as a novel gene involved in age-related hearing loss
Published 2018“…Thus, a screening of a cohort of ARHL patients and controls was carried out revealing several variants inSLC7A8, whose role was further investigated by in vitro functional studies. Significant decreases in SLC7A8 transport activity was detected for patient’s variants (p.Val302Ile, p.Arg418His, p.Thr402Met and p.Val460Glu) further supporting a causative role for SLC7A8 in ARHL. …”
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EEG-Based Semantic Vigilance Level Classification Using Directed Connectivity Patterns and Graph Theory Analysis
Published 2020“…The strength and directionality of information flow in the connectivity network by RWTE/PDC and the GTA measures significantly decrease with vigilance decrement, p<0.05. …”
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GIS-BIM Based Regional Seismic Risk Assessment for Dubai, UAE
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doctoralThesis
