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A slow but steady nanoLuc: R162A mutation results in a decreased, but stable, nanoLuc activity
Published 2024“…However, questions related to its mechanism of interaction with the substrate, furimazine, as well as bioluminescence activity remain elusive. Here, we combined molecular dynamics (MD) simulation and mutational analysis to show that the R162A mutation results in a decreased but stable <u>bioluminescence </u>activity of NLuc in living cells and in vitro. …”
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Decreased Interfacial Dynamics Caused by the N501Y Mutation in the SARS-CoV-2 S1 Spike:ACE2 Complex
Published 2022“…</p><p dir="ltr">Corrigendum: Decreased interfacial dynamics caused by the N501Y mutation in the SARS-CoV-2 S1 spike:ACE2 complex: Frontiers in Molecular Biosciences: <a href="https://dx.doi.org/10.3389/fmolb.2022.1018464" rel="noreferrer" target="_blank">https://dx.doi.org/10.3389/fmolb.2022.1018464</a>, published online 19 October 2022.…”
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Notch Signaling Inhibition by LY411575 Attenuates Osteoblast Differentiation and Decreased Ectopic Bone Formation Capacity of Human Skeletal (Mesenchymal) Stem Cells
Published 2019“…Among the tested molecules, LY411575, a potent γ-secretase and Notch signaling inhibitor, exhibited significant inhibitory effects on osteoblastic differentiation of hBMSCs manifested by reduced ALP activity, mineralized matrix formation, and decreased osteoblast-specific gene expression as well as in vivo ectopic bone formation. …”
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The Anti-Tumor Agent Sodium Selenate Decreases Methylated PP2A, Increases GSK3βY216 Phosphorylation, Including Tau Disease Epitopes and Reduces Neuronal Excitability in SHSY-5Y Neu...
Published 2019“…Somewhat surprisingly, the catalytically active form, methylated PP2A (mePP2A) was significantly decreased. In close correlation to these data, the phosphorylation state of two substrate proteins, sensitive to PP2A activity, GSK3β and Tau were found to be increased. …”
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The impact of a universal social emotional intervention on students’ mental wellbeing in a secondary public school in Qatar
Published 2023“…<p dir="ltr">This paper is based on a study that explored the impact of a practitioner-designed social emotional program on students’ wellbeing based on the results of the WEMWBS scale in a public secondary school in Qatar. …”
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Factors affecting university image among undergraduate students: the case study of qatar university
Published 2021“…The impact of university services on students’ perception of QU is further discussed based on gender, nationality, student classification, and major.…”
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“Extending the Technology Acceptance Model (TAM) to Predict University Students’ Intentions to Use Metaverse-Based Learning Platforms”
Published 2023“…A media for immersive learning, metaverse could set future educational trends and lead to significant reform in education. Although the metaverse has the potential to improve the effectiveness of online learning experiences, metaverse-based educational implementations are still in their infancy. …”
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The Effectiveness of Teaching Reading (Meta) Cognitive Strategies in Improving UAE Grade-12 Students’ Reading Comprehension Proficiency for School-based Tests and University Admiss...
Published 2015“…This study seeks to investigate the effectiveness of strategy-based instruction in improving the reading comprehension proficiency of the UAE grade twelve students in school-based tests and university admission exams like IELTS, TOEFL and CEPA after serious problems regarding reading comprehension have been reported, and many reform procedures have been taken to rectify these problems at university and pre-university levels. …”
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Effect of corporate ethics and social responsibility on OCB: the role of employee identification and perceived CSR significance
Published 2021“…The proposed model depicting the relationships is tested empirically based on data collected from a survey instrument distributed to alumni from one of the leading universities in Lebanon employed in various companies belonging to different sectors in Lebanon and the region. …”
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Indomethacin as a Rescue Therapy for Patent Ductus Arteriosus in Extremely Premature Infants after Failed Ibuprofen Treatment
Published 2023“…In our practice, we administer one or two courses of ibuprofen followed by a single course of indomethacin if the PDA has not shown closure or decrease in size on the echocardiogram (echo) exam. …”
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University students' conceptions and language learning. (c2007)
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Qatari national scholarships: University selectivity and student outcomes
Published 2015“…When the selectivity was narrowed by bifurcating students who were enrolled in highly ranked (top-200 universities) and those lower-ranked universities (below the top 200-ranked universities or non-ranked universities), a main and significant statistical difference was found for selectivity on university achievement and time of study. …”