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A slow but steady nanoLuc: R162A mutation results in a decreased, but stable, nanoLuc activity
Published 2024“…In this regard, engineering of brighter bioluminescent proteins, i.e. luciferases, has played a significant role. This is acutely exemplified by the engineering of the NLuc <u>luciferase</u>, which is small in size and displays much enhanced bioluminescence and<u> thermal stability</u> compared to previously available luciferases. …”
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Treating Cancers Using Nature’s Medicine: Significance and Challenges
Published 2021“…In recent decades, the emphasis on identifying therapeutic plant-based active principles led to significant advancements in the identification and use of natural compounds to treat various diseases (Figure 1) [2,3]. …”
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Exploring the Significance of Publication-Age-Based Parameters for Evaluating Researcher Impact
Published 2023“…In addition, these indices are often evaluated using dissimilar datasets, making it challenging to accurately compare their contributions and significance. …”
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Notch Signaling Inhibition by LY411575 Attenuates Osteoblast Differentiation and Decreased Ectopic Bone Formation Capacity of Human Skeletal (Mesenchymal) Stem Cells
Published 2019“…Among the tested molecules, LY411575, a potent γ-secretase and Notch signaling inhibitor, exhibited significant inhibitory effects on osteoblastic differentiation of hBMSCs manifested by reduced ALP activity, mineralized matrix formation, and decreased osteoblast-specific gene expression as well as in vivo ectopic bone formation. …”
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A Novel Steganography Technique for Digital Images Using the Least Significant Bit Substitution Method
Published 2022“…Therefore, the proposed work, in this paper, is based on the Least Significant Bit (LSB) substitution method. …”
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Aspect-based sentiment analysis using smart government review data
Published 2019“…Also, when using the same dataset, the proposed approach outperforms machine learning approaches that uses support vector machine (SVM). …”
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Effective use of Science Inquiry-based Teaching on Student Achievement and Engagement
Published 2019“…The sample is divided in two: the first group sample n=26, was the experimental group receiving science inquiry-based instruction, while the controlled group (n=26) followed non-inquiry-based instruction(traditional strategy).The dependent variables were the students‘ achievement and engagement which were measured through the mixed method approach: 1) quantitative data was collected using a pre- and a post-test to assess the students ‗science achievement. 2) Qualitative data was noted using an observation tool designed for the study and entitled EIT 2013 to evaluate the students‘ engagement. …”
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Educational Test Scores: Interpretation and Use through an Argument-Based Framework
Published 2025“…However, a recent approach to test score interpretation and use, the argument-based framework, will question the use of IELTS for this purpose by providing rebutalls. …”
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Effect of corporate ethics and social responsibility on OCB: the role of employee identification and perceived CSR significance
Published 2021“…Partial least square structural equation modeling (PLS-SEM) is used to analyze the data and multi-group analysis is conducted to investigate the role of perceived CSR significance. …”
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AI-based remaining useful life prediction and modelling of seawater desalination membranes
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Predicting Mobile Game Success Using Data Analytics
Published 2017“…Where success is described based on the best match with the results of the study. …”
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The Development And Significance Of Business Intelligence (BI) Platforms In Facilitating The Decision-Making Process In Dubai Government Entities
Published 2022“…Furthermore, the significance of using the BI platform for decision-making is established in the light of academic and empirical evidence. …”
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Deep random vector functional link transformer network with multiple output layers for significant wave height forecasting
Published 2025“…Forecasts are generated by integrating the outputs of each layer using an ensemble approach. The computational results demonstrate the superiority of the proposed models through a comparative analysis against state-of-the-art approaches across fifteen significant wave height time series, validated by three error metrics and a statistical test.…”
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Small molecule inhibition of stat3 enhances survival in mice with intracerebral melanoma
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Robust design of electrical power-based stabilizers using tabusearch
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