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The Anti-Tumor Agent Sodium Selenate Decreases Methylated PP2A, Increases GSK3βY216 Phosphorylation, Including Tau Disease Epitopes and Reduces Neuronal Excitability in SHSY-5Y Neu...
Published 2019“…Somewhat surprisingly, the catalytically active form, methylated PP2A (mePP2A) was significantly decreased. In close correlation to these data, the phosphorylation state of two substrate proteins, sensitive to PP2A activity, GSK3β and Tau were found to be increased. …”
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Artificial Intelligence Frameworks for Sentiment Variations’ Reasoning and Emerging Topic Detection
Published 2021“…This model can be used for multiple applications, including detection of new research trends from large sets of scientific papers, discovery of hot topics on social media, comparison of customer reviews for two products to identify their strong/weak aspects, and our focus topic of interpreting public sentiment variations. …”
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A slow but steady nanoLuc: R162A mutation results in a decreased, but stable, nanoLuc activity
Published 2024“…Here, we combined molecular dynamics (MD) simulation and mutational analysis to show that the R162A mutation results in a decreased but stable <u>bioluminescence </u>activity of NLuc in living cells and in vitro. …”
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Variation in Seasonal Precipitation over Gaza (Palestine) and Its Sensitivity to Teleconnection Patterns
Published 2021“…<div><p>The seasonal precipitation (SP) trend and its sensitivity to teleconnection patterns over the East Mediterranean (EM) region remain inconsistent. …”
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Decreased Interfacial Dynamics Caused by the N501Y Mutation in the SARS-CoV-2 S1 Spike:ACE2 Complex
Published 2022“…In this regard, the recent SARS-CoV-2 alpha, beta, and gamma variants (B.1.1.7, B.1.351, and P.1 lineages, respectively) are of great significance in that they contain several mutations that increase their transmission rates as evident from clinical reports. …”
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Monitoring the variation of soil quality with sewage sludge application rates in absence of rhizosphere effect
Published 2020“…Besides, analytical results and field observations revealed no trends of soil salinization or acidification by excessive sludge amounts. …”
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A Multidecadal Assessment of Haze Development and Fluctuations in Visibility for Arabian Peninsula
Published 2024“…To comprehend the time-based patterns of visibility across the ME, we utilized the Mann Kendall (MK) and Modified Mann Kendall (MMK) trend estimators in both space and time. The daily visibility of QTR exhibits significant variations from 1975 to 2023, with the lowest and greatest values representing the dynamic character of visibility in the region. …”
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Trends of the Dementia Burden in South Asia: An Analysis of 2021 Global Burden of Disease Study
Published 2025“…</p><h3>Results</h3><p dir="ltr">A slight decrease in incidence rates from 80.57 to 79 per 100,000 was observed, alongside a significant increase in mortality rates from 14.11 to 17.2 per 100,000. …”
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Kefir exhibits anti‑proliferative and pro‑apoptotic effects on colon adenocarcinoma cells with no significant effects on cell migration and invasion
Published 2014“…Results from RT‑PCR showed that kefir decreases the expression of transforming growth factor α (TGF‑α); and transforming growth factor‑β1 (TGF‑β1) in HT‑29 cells. …”
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Daucus carota pentane-based fractions arrest the cell cycle and increase apoptosis in MDA-MB-231 breast cancer cells
Published 2014“…The increase in apoptosis in response to treatment was also apparent in the increase in BAX and the decrease in Bcl-2 levels as well as the proteolytic cleavage of both caspase-3 and PARP as revealed by Western blot. …”
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Trends in Necrotizing Fasciitis‐Associated Mortality in the United States 2003–2020: A CDC WONDER Database Population‐Based Study
Published 2025“…Despite the urgency of this condition, there is limited research on long‐term NF‐related mortality trends in the United States.</p><h3>Objective</h3><p dir="ltr">This study aims to analyze NF‐related mortality trends in adults aged 25 and older in the United States from 2003 to 2020, focusing on variations by sex, race/ethnicity, and geographic region.…”
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High School Type as a Predictor of Student Academic Performance and Retention: A Case Study of Student Academic Performance and Retention in relation to High School type qualificat...
Published 2016“…However the findings would have been more significant with a bigger sample size. The academic performance of students enrolling in the business program after completing Intermediate/HSSC shows a more stable trend as compared to students joining the undergraduate business program after completing their GED.…”
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Alterations in blood Lipoprotein & Apolipoprotein B profile induced by moderate acute & chronic alcohol intake in the rat model. (c2002)
Published 2002“…On the other hand, a 3% alcohol consumption (as beer or whisky) maintained for a two months period did not have an effect on fasting plasma TAG concentration while total and LDL cholesterol concentrations showed a significant decrease and HDL cholesterol concentration was moderately increased. …”
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Effect of Hydroxycut Intake on Fasted and Postprandial Lipemia in Rats
Published 2015“…A significant increase in serum blood glucose level was observed with hydroxycut intake in the presence of a high-fat diet. …”
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