Decreased Analgesic Requirements in Super Morbidly Versus Morbidly Obese Patients Undergoing Laparoscopic Sleeve Gastrectomy by Hamed Elgendy (14148846)

A slow but steady nanoLuc: R162A mutation results in a decreased, but stable, nanoLuc activity by Wesam S. Ahmed (10170053)

“…However, questions related to its mechanism of interaction with the substrate, furimazine, as well as bioluminescence activity remain elusive. Here, we combined molecular dynamics (MD) simulation and mutational analysis to show that the R162A mutation results in a decreased but stable <u>bioluminescence </u>activity of NLuc in living cells and in vitro. …”

Decreased Interfacial Dynamics Caused by the N501Y Mutation in the SARS-CoV-2 S1 Spike:ACE2 Complex by Wesam S. Ahmed (10170053)

“…Additionally, we find that the N501Y mutant S1-RBD displays altered dynamics that likely aids in its enhanced interaction with ACE2. …”

L1-CAM knock-down radiosensitizes neuroblastoma IMR-32 cells by simultaneously decreasing MycN, but increasing PTEN protein expression by Rached, Johnny

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Notch Signaling Inhibition by LY411575 Attenuates Osteoblast Differentiation and Decreased Ectopic Bone Formation Capacity of Human Skeletal (Mesenchymal) Stem Cells by Nihal AlMuraikhi (6002234)

“…Among the tested molecules, LY411575, a potent γ-secretase and Notch signaling inhibitor, exhibited significant inhibitory effects on osteoblastic differentiation of hBMSCs manifested by reduced ALP activity, mineralized matrix formation, and decreased osteoblast-specific gene expression as well as in vivo ectopic bone formation. …”

Performance evaluation of 3D-printed PLA composites doped with WE43 magnesium alloy for bone tissue engineering applications by Sumama Nuthana Kalva (17302906)

“…While a low Mg content (5 %) only slightly impacted the print quality and dimensions, higher Mg concentrations (10 % and 15 %) led to increased weight, rougher surfaces, dimensional shrinkage in height, and overall poorer formation quality. Adding WE43 alloy to PLA decreased the average pore sizes of the composites. …”

Both decreasing interstructural space size and increasing total cover increase shrimp abundance on artificial structures deployed in a UAE seagrass bed by Bartholomew, Aaron

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Serum Vitamin D Concentration ≥75 nmol/L Is Related to Decreased Cardiometabolic and Inflammatory Biomarkers, Metabolic Syndrome, and Diabetes; and Increased Cardiorespiratory Fitn... by Vijay Ganji (8710491)

Indomethacin as a Rescue Therapy for Patent Ductus Arteriosus in Extremely Premature Infants after Failed Ibuprofen Treatment by Amal Sabouni (17046236)

“…While most PDAs close after one 3-day course of either medicine, a repeat course may be necessary before considering surgical ligation for those who remain with hsPDAs. In our practice, we administer one or two courses of ibuprofen followed by a single course of indomethacin if the PDA has not shown closure or decrease in size on the echocardiogram (echo) exam. …”

The Anti-Tumor Agent Sodium Selenate Decreases Methylated PP2A, Increases GSK3βY216 Phosphorylation, Including Tau Disease Epitopes and Reduces Neuronal Excitability in SHSY-5Y Neu... by Wesal Habbab (17346961)

“…Somewhat surprisingly, the catalytically active form, methylated PP2A (mePP2A) was significantly decreased. In close correlation to these data, the phosphorylation state of two substrate proteins, sensitive to PP2A activity, GSK3β and Tau were found to be increased. …”

Evidence and gaps in clinical outcomes of novel pharmacologic therapies for sickle cell disease: A systematic literature review highlighting insights from clinical trials and real-... by Mohamed Yassin (4166515)

“…The high discontinuation rate and results of the STAND trial led to a significant decrease in the use of crizanlizumab. The HOPE trial demonstrated a 51 % improvement in hemoglobin response and a reduction in hemolytic markers in patients treated with voxelotor. …”

STARD 13 in prostate cancer. (c2018) by Saab, Sahar S.

“…In this study, we investigate the role of StarD13, an inhibitor of RhoA and Cdc42 through its GAP activity, on prostate cancer cells proliferation and metastasis by manipulating its level of expression in the cells. …”
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Non-diabetic ketoacidosis secondary to primary hyperthyroidism by Abdulrahman F. Al-Mashdali (17148316)

“…This was associated with decreased appetite and weight loss.</p><h3>Diagnosis</h3><p dir="ltr">Laboratory findings were significant for high anion gap metabolic acidosis, positive ketones in the urine, and high serum B-hydroxybutyrate. …”

Frugal innovation for sustainable rural development by Mokter, Hossain

“…Using a grounded theory method and based on 22 interviews with key informants related to 13 cases of frugal enterprise in South Asia, this qualitative study attempts to accomplish the aim of the study. We developed a classification that identifies the increasing positive and decreasing negative parameters of SDGs to assess the extent to which frugal enterprises contribute to specific SDGs. …”
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The Effect of HuArgI (Co)-PEG5000 on The Migration of Ovarian Cancer by El Mais, Nour

“…HuArgI (Co)-PEG5000 is a potential drug to target cancers that depend on exogenous sources of arginine and cannot synthesize their own. In this study, we hypothesized that HuArgI (Co)- PEG5000 can decrease the migration of ovarian cancer cells. …”
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Crystallization properties of arsenic doped GST alloys by Vinod E. Madhavan (8136774)

“…The decreases in E_opt for the samples annealed at higher temperatures shows significant optical contrast between the as-deposited and annealed samples. …”

Frugal innovation for sustainable rural development by Mokter Hossain (14634969)

“…Using a grounded theory method and based on 22 interviews with key informants related to 13 cases of frugal enterprise in South Asia, this qualitative study attempts to accomplish the aim of the study. We developed a classification that identifies the increasing positive and decreasing negative parameters of SDGs to assess the extent to which frugal enterprises contribute to specific SDGs. …”

Exploring the Role of Perceived Organizational Injustice and Organizational Identification in the Impact of Discretionary HR Practices on Counterproductive Behaviors: Evidence from... by El Dimassi, Yasmeen

“…It investigates how customized, flexible HR practices are resource-enhancing tools that decrease workplace deviant behaviors. The study uses survey responses from 214 Lebanese employees working in different sectors to fill a significant knowledge gap in HR studies, primarily focusing on Western business settings. …”
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The Effect of Recombinant Anthrax Lethal Toxin on Breast Cancer Cell Motility, Adhesion, and Invasion by El Chami, Dana

“…Cells treated with LT showed a significant decrease in motility as seen in 2D time-lapse and wound healing assays. …”
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Antecedents and consequences on employee turnover intention in the hospitality industry in Lebanon by Baajour, Maya

“…H1 (There is an indirect relationship between PAT and Turnover) showed a significant result that when training is available employees’ intention to leave decreases. …”
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