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A slow but steady nanoLuc: R162A mutation results in a decreased, but stable, nanoLuc activity
Published 2024“…Here, we combined molecular dynamics (MD) simulation and mutational analysis to show that the R162A mutation results in a decreased but stable <u>bioluminescence </u>activity of NLuc in living cells and in vitro. …”
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The Anti-Tumor Agent Sodium Selenate Decreases Methylated PP2A, Increases GSK3βY216 Phosphorylation, Including Tau Disease Epitopes and Reduces Neuronal Excitability in SHSY-5Y Neu...
Published 2019“…Somewhat surprisingly, the catalytically active form, methylated PP2A (mePP2A) was significantly decreased. In close correlation to these data, the phosphorylation state of two substrate proteins, sensitive to PP2A activity, GSK3β and Tau were found to be increased. …”
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Cost analysis of agricultural greenhouse yield production using spectrum selective fluids
Published 2024“…Greenhouses offer crop protection but require significant energy, especially for cooling in hot climates. …”
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The genetic basis and the diagnostic yield of genetic testing related to nonsyndromic hearing loss in Qatar
Published 2024“…The overall diagnostic yield was 30.7%, and the diagnostic yield was significantly associated with genetic testing using <i>GJB2</i> sequencing and using the hearing loss (HL) gene panel. …”
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Do detection-based warning strategies improve vehicle yielding behavior at uncontrolled midblock crosswalks?
Published 2021“…The results showed that both the LED and VMS conditions were helpful in increasing yielding rates up to 98.4 % and reducing the vehicle-pedestrian conflicts significantly. …”
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Biochar yield prediction using response surface methodology: effect of fixed carbon and pyrolysis operating conditions
Published 2023“…<p dir="ltr">Generating value from wastes via pyrolysis has been increasingly researched in recent times. Biochar is a versatile pyrolysis product with yields based on many process parameters, including feedstock type and particle size, and operating conditions such as pyrolysis reactor, heating rate, residence time, and reaction temperature. …”
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Enhancing eggplant (Solanum melongena L.) yield and water use efficiency through optimized irrigation and nitrogen practices in open field conditions
Published 2024“…While average fruit weight did not differ significantly across nitrogen levels, the highest fruit yield was recorded under F1 and F2 treatments. …”
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Reduced fertigation input sustains yield and physiological performance for improved economic returns and cleaner production of greenhouse eggplant
Published 2024“…Yield analysis revealed a negative correlation between eggplant yield and increasing EC levels, with optimal yields in both eggplant varieties (0.81 and 1.14 kg m−2 week−1 in Lydia and Tracey, respectively) achieved at the lowest EC. …”
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Decreased Interfacial Dynamics Caused by the N501Y Mutation in the SARS-CoV-2 S1 Spike:ACE2 Complex
Published 2022“…<p dir="ltr">Coronavirus Disease of 2019 (COVID-19) caused by Severe Acute Respiratory Syndrome Coronavirus 2 (SARS-CoV-2) has resulted in a massive health crisis across the globe, with some genetic variants gaining enhanced infectivity and competitive fitness, and thus significantly aggravating the global health concern. …”
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Indomethacin as a Rescue Therapy for Patent Ductus Arteriosus in Extremely Premature Infants after Failed Ibuprofen Treatment
Published 2023“…<p dir="ltr">Hemodynamically significant patent ductus arteriosus (hsPDA) is a major cause of neonatal morbidity and mortality in extremely low birth weight (ELBW) infants. …”
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Notch Signaling Inhibition by LY411575 Attenuates Osteoblast Differentiation and Decreased Ectopic Bone Formation Capacity of Human Skeletal (Mesenchymal) Stem Cells
Published 2019“…Among the tested molecules, LY411575, a potent γ-secretase and Notch signaling inhibitor, exhibited significant inhibitory effects on osteoblastic differentiation of hBMSCs manifested by reduced ALP activity, mineralized matrix formation, and decreased osteoblast-specific gene expression as well as in vivo ectopic bone formation. …”
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Kefir exhibits anti‑proliferative and pro‑apoptotic effects on colon adenocarcinoma cells with no significant effects on cell migration and invasion
Published 2014“…Our data suggest that kefir is able to inhibit the proliferation and induce apoptosis in HT‑29 and Caco‑2 CRC cells, yet it does not exhibit a significant effect on the motility and invasion of these cells in vitro.…”
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Upgrading co-pyrolysis products from ternary biomass: An investigative study of commercial and locally-made catalysts
Published 2024“…<p dir="ltr">Catalysts play a pivotal role in influencing product yields and compositions in pyrolysis processes, offering significant advantages for biomass conversion. …”