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A slow but steady nanoLuc: R162A mutation results in a decreased, but stable, nanoLuc activity
Published 2024“…Here, we combined molecular dynamics (MD) simulation and mutational analysis to show that the R162A mutation results in a decreased but stable <u>bioluminescence </u>activity of NLuc in living cells and in vitro. …”
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The effectiveness of physical models in teaching anatomy
Published 2016“…The aim of this meta-analysis is to quantitatively assess the effectiveness of such models based on comparative studies. …”
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Detection of statistically significant network changes in complex biological networks
Published 2017“…</p><h3>Methods</h3><p dir="ltr">In this paper, we propose an improvement over the state-of-the-art based on the Generalized Hamming Distance adopted for evaluating the topological difference between two networks and estimating its statistical significance. The proposed procedure exploits a more effective model selection criteria to generate <i>p</i>-values for statistical significance and is more efficient in terms of computational time and prediction accuracy than literature methods. …”
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The Anti-Tumor Agent Sodium Selenate Decreases Methylated PP2A, Increases GSK3βY216 Phosphorylation, Including Tau Disease Epitopes and Reduces Neuronal Excitability in SHSY-5Y Neu...
Published 2019“…Somewhat surprisingly, the catalytically active form, methylated PP2A (mePP2A) was significantly decreased. In close correlation to these data, the phosphorylation state of two substrate proteins, sensitive to PP2A activity, GSK3β and Tau were found to be increased. …”
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Contagion effects in a chartist–fundamentalist model with time delays
Published 2007“…In this paper two models of speculative markets are developed to study the effects of feedback mechanisms in financial markets. …”
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Non-Newtonian Effects in a Fluid-Structure Interaction Model for Atherosclerosis
Published 2009“…The simulations show that the Newtonian model significantly overestimates the recirculations in comparison with the non-Newtonian model. …”
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Effects of Dunn and Dunn learning styles model on achievement and motivation. (c2013)
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Staff Development: A Study Into The Significance of Staff Professional Development Programs for Educators and Students Achievement
Published 2011“…The concept of staff professional development and its effectiveness has been a key area of discussion for long. …”
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Potential Therapeutic Effects of Lebanese Cannabis oil in Female Mouse Models of Neuropsychiatric Disorders
Published 2022“…Accordingly, the current research study examined the therapeutic effects of Cannabis oil extracted from the Lebanese Cannabis sativa plant on resilience to stress and its ability to rescue depression and anxiety-like behaviors in female animal models. …”
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Stability and bifurcation analysis of a discrete-time predator-prey model with strong Allee effect
Published 2020“…In this paper, we investigate the impact of Allee effect on the stability of a discrete-time predator-prey model with a non-monotonic functional response. …”
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Decreased Interfacial Dynamics Caused by the N501Y Mutation in the SARS-CoV-2 S1 Spike:ACE2 Complex
Published 2022“…<p dir="ltr">Coronavirus Disease of 2019 (COVID-19) caused by Severe Acute Respiratory Syndrome Coronavirus 2 (SARS-CoV-2) has resulted in a massive health crisis across the globe, with some genetic variants gaining enhanced infectivity and competitive fitness, and thus significantly aggravating the global health concern. …”
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Anticancer Effects of Lebanese Cannabis Oil Against in vivo and in vitro Models of Squamous Cell Carcinoma
Published 2023“…Intraperitoneal treatment of mice with COE (10, 25 or 50 mg/kg; 9 weeks) showed a non-significant decrease in tumor volume with respect to control, without adverse effects on liver and kidney function. …”
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How effective are synthetic attack models to detect real-world energy theft?
Published 2025“…However, available datasets lack annotated real anomalies, which poses significant challenges in developing effective detection systems. …”
