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Activation of Src kinase in primary colorectal carcinoma An indicator of poor clinical prognosis
Published 2002“…BACKGROUND The specific activity of the non-receptor protein tyrosine kinase, Src, is increased in the majority of colon and rectal adenocarcinomas compared to normal mucosa. …”
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Deep learning-based modeling of land use/land cover changes impact on land surface temperature in Greater Amman Municipality, Jordan (1980–2030)
Published 2024“…This study aimed to model past, present, and future LULCC on Land Surface Temperatures in the Greater Amman Municipality (GAM) in Jordan between 1980 and 2030. …”
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Characterization of the Potency and Mechanism of Action of a Novel Dual-Selective Intermolecularly Complemented Version of Anthrax Lethal Toxin (PAU2R200A- PAL1I207R/FP59) in Breas...
Published 2023“…Following cell entry, LF cleaves all mitogen- activated protein kinase kinase (MEKs) leading to the inactivation of the MAPK pathway. …”
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Selective ROCK Inhibitor Enhances Blood Flow Recovery after Hindlimb Ischemia
Published 2023“…At the histological level, we found that GSK429286 significantly increased the size of new microvessels in the regenerating areas of ischemic muscles compared with vehicle-treated ones. …”
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The Effect of Recombinant Anthrax Lethal Toxin on Breast Cancer Cell Motility, Adhesion, and Invasion
Published 2020“…Additionally, cells treated with LT showed an increase in adhesion, decrease in invasion across a collagen matrix, and in increase in Rho A activation. …”
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The Safety of Novel Therapies in Chronic Lymphocytic Leukemia in the Era of Intermittent Fasting: A Pharmacology-Based Review
Published 2024“…Concurrently, novel agents (NAs) like venetoclax and Bruton tyrosine kinase inhibitors (BTKIs) have revolutionized the treatment of chronic lymphocytic leukemia (CLL). …”
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Visitors off the trail: Impacts on the dominant plant, bryophyte and lichen species in alpine heath vegetation in sub-arctic Sweden
Published 2021“…With a greater decrease in taller forbs and shrubs than in graminoids and prostrate plants, a greater decrease in lichen than in bryophyte species, and a change in vegetation composition. …”
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Mechanical stretch and prostaglandin E2 modulate critical signaling pathways in mouse podocytes
Published 2010“…Finally, mechanical stretch alone or in combination with HG, induced ERK1/2 and JNK activation, via the EGF receptor since AG1478, a specific EGF receptor kinase inhibitor, blocked this activation. These results show that cellular signaling in podocytes is significantly altered under diabetic conditions (i.e., hyperglycemia and increased Pgc). …”
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Clinical correlates of white-matter abnormalities on head magnetic resonance imaging
Published 2001“…The children with white-matter abnormalities and decreased tone had significantly less signal intensity abnormality than the other study groups. …”
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Stimulation of sphingosine 1-phosphate signaling as an alveolar cell survival strategy in emphysema
Published 2010“…Measurements and Main Results: Consistent with previously reported de novo activation of ceramide synthesis, VEGFR inhibition triggered increases in lung ceramides, dihydroceramides, and dihydrosphingosine, but did not alter sphingosine kinase activity or S1P levels. …”
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Colloid retention and mobilization mechanisms under different physicochemical conditions in porous media: A micromodel study
Published 2021“…However, for hydrophobic colloids, changes in solution chemistry significantly increase colloid retention where the colloid interaction become attractive with the increase in ionic strength and decrease in pH values. …”
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Parallel multi-voltage power minimization in VLSI circuits. (c2013)
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Optimizing the number of players and training bout durations in soccer small‐sided games: Effects on mood balance and technical performance
Published 2025“…Therefore, coaches should consider longer continuous bouts when planning SSGs‐based training to significantly decrease TMD and enhance technical‐tactical performance in soccer SSGs.…”
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Effect of Crude Oil Products on the Geotechnical Properties of Sandy Soil
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doctoralThesis