Addition of sphingosine-1-phosphate to human oocyte culture medium decreases embryo fragmentation by Zreik, Tony

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Activation of Src kinase in primary colorectal carcinoma An indicator of poor clinical prognosis by Allgayer, Heike

“…BACKGROUND The specific activity of the non-receptor protein tyrosine kinase, Src, is increased in the majority of colon and rectal adenocarcinomas compared to normal mucosa. …”
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Anti-xa guided enoxaparin thromboprophylaxis is associated with less thromboembolism than fixed dose dalteparin in trauma patients admitted to intensive care by Ahmad Kloub (16855149)

Curcumin Induces Apoptotic Cell Death via Inhibition of PI3-Kinase/AKT Pathway in B-Precursor Acute Lymphoblastic Leukemia by Shilpa Kuttikrishnan (3520079)

Characterization of the Potency and Mechanism of Action of a Novel Dual-Selective Intermolecularly Complemented Version of Anthrax Lethal Toxin (PAU2R200A- PAL1I207R/FP59) in Breas... by Basala, Sobhiya

“…Following cell entry, LF cleaves all mitogen- activated protein kinase kinase (MEKs) leading to the inactivation of the MAPK pathway. …”
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Selective ROCK Inhibitor Enhances Blood Flow Recovery after Hindlimb Ischemia by Hend Salah Fayed (17732622)

“…At the histological level, we found that GSK429286 significantly increased the size of new microvessels in the regenerating areas of ischemic muscles compared with vehicle-treated ones. …”

The Effect of Recombinant Anthrax Lethal Toxin on Breast Cancer Cell Motility, Adhesion, and Invasion by El Chami, Dana

“…Additionally, cells treated with LT showed an increase in adhesion, decrease in invasion across a collagen matrix, and in increase in Rho A activation. …”
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Characterization of the potency and mechanism of action of a novel dual-selective intermolecularly complemented version of Anthrax Lethal Toxin (PAU2R200A- PAL1I207R/FP59) in Acute... by Farhat, Mirna

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The Safety of Novel Therapies in Chronic Lymphocytic Leukemia in the Era of Intermittent Fasting: A Pharmacology-Based Review by Maria Benkhadra (19756941)

“…Concurrently, novel agents (NAs) like venetoclax and Bruton tyrosine kinase inhibitors (BTKIs) have revolutionized the treatment of chronic lymphocytic leukemia (CLL). …”

Mechanical stretch and prostaglandin E2 modulate critical signaling pathways in mouse podocytes by Faour, Wissam

“…Finally, mechanical stretch alone or in combination with HG, induced ERK1/2 and JNK activation, via the EGF receptor since AG1478, a specific EGF receptor kinase inhibitor, blocked this activation. These results show that cellular signaling in podocytes is significantly altered under diabetic conditions (i.e., hyperglycemia and increased Pgc). …”
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Stimulation of sphingosine 1-phosphate signaling as an alveolar cell survival strategy in emphysema by Diab, Khalil J.

“…Measurements and Main Results: Consistent with previously reported de novo activation of ceramide synthesis, VEGFR inhibition triggered increases in lung ceramides, dihydroceramides, and dihydrosphingosine, but did not alter sphingosine kinase activity or S1P levels. …”
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Effect of Crude Oil Products on the Geotechnical Properties of Sandy Soil by Shaheen, Ehab Taher

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Cardioprotective effect of Sanguisorba minor against isoprenaline-induced myocardial infarction in rats by Azar Hosseini (33501)

“…Despite available drugs, there is still an increased need to look for alternative therapies or identify new bioactive compounds. …”

The efficacy of transcranial direct current stimulation in patients with medication overuse headaches secondary to chronic migraines (P4.128) by Ahdab, Rechdi

“…There was also a significant decrease in the consumption of analgesic medications in the DLPFC group and in the pain intensity in the Occipital group. …”
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Bond durability of sand coated and ribbed basalt FRP bars embedded in high-strength concrete by Abathar Al-Hamrani (16494884)

“…Ribbed bars had significantly higher bond strength than sand-coated bars and were less affected by the surrounding environments. …”

The differential impact of IFRS adoption on aspects of seasoned equity offerings in the UK and France by Harakeh, Mostafa

“…Given that equity financing becomes less costly, we find that the propensity to issue new SEOs increases among high-divergence firms after IFRS adoption. …”
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An Exploration of Smoking Patterns Among People with Serious Mental Illness Attending an Outpatient Clinic in Qatar by Monica Zolezzi (10115698)

“…Many countries worldwide have observed a decrease in the prevalence of tobacco smoking; however, the smoking rates among people with SMI have declined much less than in those without mental illness. …”

20-HETE and EETs in Diabetic Nephropathy: A Novel Mechanistic Pathway by Stephanie Eid (440990)

“…In conclusion, we show that hyperglycemia in diabetes has a significant effect on the expression of Arachidonic Acid (AA)-metabolizing CYPs, manifested by increased AA metabolism, and might thus alter kidney function through alteration of type and amount of AA metabolites.…”

A novel inhibitor of signal transducers and activators of transcription 3 activation is efficacious against established central nervous system melanoma and inhibits regulatory T ce... by Abou-Ghazal, Mohamed

“…Although WP1066 did not induce immunologic memory or enhance humoral responses to EGFRvIII, this compound reduced the production of immunosuppressive cytokines and chemokines (transforming growth factor-β, RANTES, MCP-1, vascular endothelial growth factor), markedly inhibited natural and inducible Treg proliferation, and significantly increased cytotoxic immune responses of T cells. …”
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Estimation of Virtual Trust on Driverless Cars using Type-1 Fuzzy logic by Mohamed Kayed Alhyasat, Khaled

“…These vehicles boost confidence, increase road capacity, and decrease traffic accident. The major benefit is a decrease in traffic enforcement, plus self-driving cars consume less fuel than other types of vehicles and don't require auto insurance. …”
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