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A slow but steady nanoLuc: R162A mutation results in a decreased, but stable, nanoLuc activity
Published 2024“…Here, we combined molecular dynamics (MD) simulation and mutational analysis to show that the R162A mutation results in a decreased but stable <u>bioluminescence </u>activity of NLuc in living cells and in vitro. …”
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Does standalone phacoemulsification lower intraocular pressure in glaucomatous eyes? A systematic review and meta-analysis
Published 2025“…In conclusion, standalone phacoemulsification significantly lowers IOP and reduces the need for glaucoma medications in patients with glaucoma.…”
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Modification of glucocorticoid effects on body weight gain, plasma lipids by changes in diet composition
Published 2003“…Prednisolone-treated groups revealed significantly lower intestinal absorption. However, prednisolone-treated high-carbohydrate (HC) fed rats showed significantly higher weight gain, concomitant with a significant increase in feed efficiency. …”
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Renewable Energy, Coal as a Baseload Power Source, and Greenhouse Gas Emissions: Evidence from U.S. State-Level Data
Published 2017“…After controlling for other sources of emissions, U.S. states that produce a larger share of renewable energy are found to have lower GHG emissions. …”
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High phosphorus diet mitigates impairments in lipid and glucose metabolism associated with diet-induced obesity in male sprague dawley rats
Published 2016“…P supplementation normalized glycemia at 2 hours in HFHP group (113±5.4 mg/dl). Fasting insulin increased significantly (p=0.008) in HF (2.8±0.4ng/ml) vs. control (1.2±0.4ng/ml) but was not different in HFHP group (2.2±0.5ng/ml). …”
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Intermittent nesiritide therapy in outpatients with chronic heart failure
Published 2005“…Heart failure (HF) continues to be a significant health problem in the United States. …”
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Why do some countries produce more capital intensive output than others?
Published 2016“…Based on my model I offer an explanation for the variation in physical capital intensity across countries where the model predictions show that a lower quality of governance in a country results in a decrease in the output of capital-intensive goods and an increase in the output of labor-intensive goods. …”
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Peripherally injected cholecystokinin-induced neuronal activation is modified by dietary composition in mice
Published 2010“…In addition, a significant interaction was found between CCK administration and the HF diet, shown by an increased activation in the PVN, which suggests a decrease the inhibiting action of CCK. …”
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Cafeteria diet-fed mice is a pertinent model of obesity-induced organ damage
Published 2015“…Additionally, consumption of the CAF diet was associated with significantly higher weight gain, abdominal fat, and serum IL-6 levels, as well as more damage in the heart (coronary perivascular fibrosis and steatosis), kidney (chronic interstitial inflammation and glomerular sclerosis), and liver (liver weight, portal fibrosis, apoptosis, and steatosis) compared to the HF diet. …”
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Changes in the burden and underlying causes of heart failure in the Eastern Mediterranean Region, 1990–2019: an analysis of the Global Burden of Disease Study 2019
Published 2023“…FindingsIn contrast with the decreasing trend of HF burden globally, EMR showed an increasing trend. …”
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Association Between Three-Months Vitamin D Supplementation and Depressive Symptomatology incidence among Saudi Arabian Adults
Published 2022“…Furthermore, the change between both groups was significantly different (-7.61 ±4.03 in the Vitamin D group, -3.50±1.54 in the control group; p=<0.001) Conclusion: The present study shows thata 50.000 IU/week dose of vitamin D supplementation for 3 months was enough to increase vitamin D levels beyond sufficient and decrease depression symptoms in Saudi Arabian Adults. …”
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Rhus coriaria L. (Sumac) Demonstrates Oncostatic Activity in the Therapeutic and Preventive Model of Breast Carcinoma
Published 2020“…Finally, only in lower sumac dose, significant decreases in methylation status of three out of five gene promoters–ATM, PTEN, and TIMP3 (PITX2 and RASSF1 promoters were not changed). …”
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Use of Animal Models for Investigating Cardioprotective Roles of SGLT2 Inhibitors
Published 2023“…The mechanism of action of an SGLT2 inhibitor (SGLT2i) in treating T2DM depends on lowering blood glucose levels effectively via increasing the glomerular excretion of glucose. A good number of randomized clinical trials revealed that SGLT2is significantly prevented heart failure (HF) and cardiovascular death in T2DM patients. …”
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Effects of habitat complexity on the abundance, species richness and size of darkling beetles (Tenebrionidae) in artificial vegetation
Published 2016“…At the high levels of habitat complexity used in this study, the main effect of increasing complexity was excluding beetles from higher complexity treatments, particularly larger beetle species. The 6 mm (highest complexity) treatment had significantly lower abundance than the other three treatments. …”
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A cafeteria diet modifies the response to chronic variable stress in rats
Published 2012“…In addition, there was a significant interaction between stress and diet on serum corticosterone levels, which manifest as an increase in corticosterone levels in stressed rats relative to non-stressed controls in the HC and HF groups but not in the CAF group. …”
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Optimisation of PV Cleaning Practices: Comparison Between Performance Based and Periodic Based Approaches
Published 2018“…Higher relative humidity, drier desert climates, larger dust particles/concentration, and lower PV panel tilt angle are all examples of how soiling or its effects are increased. …”
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Qatar’s immigrants at higher risk of diabetes
Published 2015“…The researchers stress, however, that their preliminary results should be confirmed in future studies involving larger numbers of participants. 1 “We would advise the Qatari government to screen all immigrants entering the country, as this would decrease the risk of unnecessary complications due to the late diagnosis of diabetes,” says lead author Dennis Mook-Nakamori. …”