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A slow but steady nanoLuc: R162A mutation results in a decreased, but stable, nanoLuc activity
Published 2024“…Here, we combined molecular dynamics (MD) simulation and mutational analysis to show that the R162A mutation results in a decreased but stable <u>bioluminescence </u>activity of NLuc in living cells and in vitro. …”
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Does standalone phacoemulsification lower intraocular pressure in glaucomatous eyes? A systematic review and meta-analysis
Published 2025“…In conclusion, standalone phacoemulsification significantly lowers IOP and reduces the need for glaucoma medications in patients with glaucoma.…”
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A systematic search for DNA methyltransferase polymorphisms reveals a rare DNMT3L variant associated with subtelomeric hypomethylation
Published 2009“…Polymorphisms leading to an amino acid change were further investigated for changes in global DNA methylation by differential methylation hybridization. This analysis revealed that a rare change at DNMT3L (R271Q) was associated with significant DNA hypomethylation. …”
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Host Genetic Variants Potentially Associated With SARS-CoV-2: A Multi-Population Analysis
Published 2020“…Analysis of Qatari genomes revealed significantly lower AF of risk variants linked to SARS-CoV-1 severity (CCL2, MBL, CCL5, AHSG, and IL4) compared to that of 1000Genome and/or the EAS population (up to 25-fold change). …”
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Rhus coriaria L. (Sumac) Demonstrates Oncostatic Activity in the Therapeutic and Preventive Model of Breast Carcinoma
Published 2020“…Finally, only in lower sumac dose, significant decreases in methylation status of three out of five gene promoters–ATM, PTEN, and TIMP3 (PITX2 and RASSF1 promoters were not changed). …”
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Validity and gender issues in the use of the DISCOVER. Assessment for the identification of gifted minorities
Published 1998“…Also, 22% of kindergarten, 27% of fourth- and fifth-grade, and 44% of sixth-grade participants were identified as gifted. Chi-square tests revealed no overall significant differences in the number of boys and girls identified as gifted. …”
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Symptoms of depression and anxiety in anorexia nervosa
Published 2014“…For those with AN, psychological, nutritional and biological parameters improved significantly during hospitalisation. Levels of serotonin markers were significantly lower in the AN group compared to the control group, at admission and at discharge. …”
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Renal Function Decline in Recipients and Donors of Kidney Grafts
Published 2015“…In living donors, renal function decline after the first year corresponded to 0.7 ml/min/1.73 m2, was significantly lower than that of recipients (p < 0.001), and was determined by donor age at nephrectomy. …”
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Morphological changes in amblyopic eyes in choriocapillaris and Sattler’s layer in comparison to healthy eyes, and in retinal nerve fiber layer in comparison to fellow eyes through...
Published 2021“…The mean reflectivity of the choriocapillaris and Sattler’s layer in amblyopic eyes were significantly lower than in healthy eyes (p = 0.003 and p = 0.008 respectively). …”
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The Protective Effects of Daucus carota L. ssp. carota and Cannabis sativa L. Extracts against Cisplatin Induced Nephrotoxicity in Animal Models
Published 2021“…In addition, COE treatment caused a significant decrease in urinary albumin excretion. Furthermore, Western blot analysis with the antibodies against COX-2 was significantly lower in cisplatin-intoxicated mice with COE in comparison to mice treated with cisplatin alone. …”
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Ribosomal DNA Copy Number Variation is Coupled with DNA Methylation Changes at the 45S rDNA Locus
Published 2023“…The 45S rDNA locus encodes essential components of the cell, nevertheless rDNA displays high inter-individual CN variation that could influence human health and disease. …”
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Modification of glucocorticoid effects on body weight gain, plasma lipids by changes in diet composition
Published 2003“…Prednisolone-treated groups revealed significantly lower intestinal absorption. However, prednisolone-treated high-carbohydrate (HC) fed rats showed significantly higher weight gain, concomitant with a significant increase in feed efficiency. …”
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High flow nasal oxygen (HFNO) in the treatment of COVID-19 infection of adult patients from – An emergency perspective: A systematic review and meta-analysis
Published 2023“…Our statistical analysis has shown that significantly lower ROX index (5.07 ± 1.66, p = 0.028) and PaO2/FiO2 (100 ± 27.51, p = 0.031) are associated with HFNO failure, while a significantly lower respiratory rate (RR) (23.17 ± 4.167, p = 0.006) is associated with HFNO success. …”
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Parallel multi-voltage power minimization in VLSI circuits. (c2013)
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Exploring the Role of Perceived Organizational Injustice and Organizational Identification in the Impact of Discretionary HR Practices on Counterproductive Behaviors: Evidence from...
Published 2025“…Organizational identification failed to influence the relationship between injustice and CWBs, nor did it significantly lower the likelihood of harmful workplace conduct. …”
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