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The Anti-Tumor Agent Sodium Selenate Decreases Methylated PP2A, Increases GSK3βY216 Phosphorylation, Including Tau Disease Epitopes and Reduces Neuronal Excitability in SHSY-5Y Neu...
Published 2019“…Somewhat surprisingly, the catalytically active form, methylated PP2A (mePP2A) was significantly decreased. In close correlation to these data, the phosphorylation state of two substrate proteins, sensitive to PP2A activity, GSK3β and Tau were found to be increased. …”
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Machine Learning in the Analysis of Social Problems: The Case of Global Human Trafficking
Published 2019“…However, it has received mixed outlook in the social science field. This study aims to use the methods of learning from real data set on human trafficking, which is a serious social problem of today. …”
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Estimating the elastic constants of orthotropic composites using guided waves and an inverse problem of property estimation
Published 2024“…The results demonstrate that formulation of property estimation as inverse problem is capable of accurately predicting the elastic constants of a material, by using a model solely trained on simulation and a very scare amount of data. …”
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Dissecting drayage
Published 2010“…This uncertainty leads to much difficulty and inefficiency in planning a profitable routing for multiple containers in one day. We study this problem from three perspectives using both empirical and theoretical techniques.…”
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Autonomous Vehicles Delivery Systems: Analyzing Vehicle Routing Problems with a Moving Depot
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Problem Posing. (c2015)
Published 2015“…The current research explores the effectiveness of using problem posing as a teaching strategy to enhance students’ problem solving abilities. …”
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Examining engineering students' perceptions of learner agency enactment in problem‐ and project‐based learning using Q methodology
Published 2023“…A 40-item Q set based on a theoretical model of learner agency was used.</p> <h3> Results</h3> <p>Eight significantly different student viewpoints emerged from the Q methodological factor analysis, indicating a range of individual perceptions of learner agency. …”
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A slow but steady nanoLuc: R162A mutation results in a decreased, but stable, nanoLuc activity
Published 2024“…Here, we combined molecular dynamics (MD) simulation and mutational analysis to show that the R162A mutation results in a decreased but stable <u>bioluminescence </u>activity of NLuc in living cells and in vitro. …”
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Impact of Using the Self-Study Guide to Reduce the Negative Effects of Teachers’ Turnover on Students’ Performance: a Study Conducted in a Private American School in Abu Dhabi
Published 2019“…A mixed-approach (quantitative- qualitative) is used to detect the success of using the proposed Guide to solve the Turnover problem. …”
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Decreased Interfacial Dynamics Caused by the N501Y Mutation in the SARS-CoV-2 S1 Spike:ACE2 Complex
Published 2022“…In this regard, the recent SARS-CoV-2 alpha, beta, and gamma variants (B.1.1.7, B.1.351, and P.1 lineages, respectively) are of great significance in that they contain several mutations that increase their transmission rates as evident from clinical reports. …”
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Reduced graphene aerogels as energy efficient selective oil sorbents
Published 2022“…The presence of H<sub>2</sub> significantly decreased the oxygen-containing functional groups in graphene aerogel. …”
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The multi-parameterized cluster editing problem
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Self-reported awareness and attitude of cancer patients towards clinical nurse coordinators
Published 2017“…Methods: This is a cross sectional study that was conducted by distributing a self-reported and anonymous survey to 240 cancer patients visiting the center. …”
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Notch Signaling Inhibition by LY411575 Attenuates Osteoblast Differentiation and Decreased Ectopic Bone Formation Capacity of Human Skeletal (Mesenchymal) Stem Cells
Published 2019“…Among the tested molecules, LY411575, a potent γ-secretase and Notch signaling inhibitor, exhibited significant inhibitory effects on osteoblastic differentiation of hBMSCs manifested by reduced ALP activity, mineralized matrix formation, and decreased osteoblast-specific gene expression as well as in vivo ectopic bone formation. …”
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A clustering metaheuristic for large orienteering problems
Published 2022“…We have validated the effectiveness of the proposed metaheuristic design through a set of computational experiments. In particular, using a state-of-the-art heuristic and an exact algorithm, we have shown that it is significantly beneficial to use the Orienteering Problem algorithm plugged into our metaheuristic, as opposed to using it as a standalone algorithm. …”
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Scalable parallel algorithms for difficult combinatorial problems
Published 2004“…These complementary tools and technologies are used to launch systematic attacks on combinatorial problems of significance. …”
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The Impact of the REACT Strategy on the Academic Achievement and Problem-Solving Skills of the Twelfth-Grade Students in Biology in the United Arab Emirates
Published 2024“…This shows the significant effect of the REACT strategy in improving academic achievement and problem-solving skills in biology before applying the strategy. …”
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