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Notch Signaling Inhibition by LY411575 Attenuates Osteoblast Differentiation and Decreased Ectopic Bone Formation Capacity of Human Skeletal (Mesenchymal) Stem Cells
Published 2019“…Among the tested molecules, LY411575, a potent γ-secretase and Notch signaling inhibitor, exhibited significant inhibitory effects on osteoblastic differentiation of hBMSCs manifested by reduced ALP activity, mineralized matrix formation, and decreased osteoblast-specific gene expression as well as in vivo ectopic bone formation. …”
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Gender differences in personal values
Published 2015“…There were no significant differences between males and females on personal values concerned with the “vision” factor. …”
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Board composition, CEO turnover and firm value
Published 2016“…Consequently, we investigate the implications of board composition changes on CEO turnover and firm value. We document a significant reduction in CEO turnover in the post-SOX period. …”
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Corporate Governance, Disclosure Content and Shareholder Value
Published 2013“…Banks market capitalisation dropped significantly, risk levels increased and stakeholders’ confidence was shaken. …”
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A slow but steady nanoLuc: R162A mutation results in a decreased, but stable, nanoLuc activity
Published 2024“…In this regard, engineering of brighter bioluminescent proteins, i.e. luciferases, has played a significant role. This is acutely exemplified by the engineering of the NLuc <u>luciferase</u>, which is small in size and displays much enhanced bioluminescence and<u> thermal stability</u> compared to previously available luciferases. …”
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Performance and microbial community variations of anaerobic digesters under increasing tetracycline concentrations
Published 2017“…Results revealed that for all of the tested tetracycline concentrations, no major sustained impact on methane production was observed. Instead, a significant increase in propionic acid was observed in the reactor subjected to the highest concentration of tetracycline (20 mg/L). …”
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Genetic Basis and Prognostic Value of Exercise QT Dynamics
Published 2020“…We also did not observe associations of QT dynamics during exercise and recovery with cardiovascular events. Increased QT dynamics during recovery was significantly associated with all-cause mortality in the univariate Cox regression analysis (hazard ratio, 1.09 [95% CI, 1.05–1.13], P =2.28×10 -5 ), but the association was not significant after adjusting for clinical risk factors.…”
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Essays on the effect of excess compensation and governance changes on firm value
Published 2012“…The third essay examines the relationship between the firm’s governance structure and its value during different economic conditions. We show that both relative industry turnover and CEO entrenchment increase during economic downturns. …”
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Small molecule inhibition of stat3 enhances survival in mice with intracerebral melanoma
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Sensitivity analysis of work plane illuminance to room surface reflectance values
Published 2018“…For the purpose of proving it , two digital models were created in this study in order to run the simulations. Significantly, the small area office illuminance increased with high values when the wall surface reflectance is high . …”
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The effect of CEO ownership & CEO entrenchment on firm value. (c2011)
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Targeted Inactivation of Rin3 Increases Trabecular Bone Mass by Reducing Bone Resorption and Favouring Bone Formation
Published 2021“…Mean ± standard deviation values at the distal femur at 8 weeks were 9.0 ± 2.5 vs. 7.0 ± 1.5 (p = 0.002) and at 52 weeks were 15.8 ± 9.5 vs. 8.5 ± 4.2 (p = 0.002). …”
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Toward a Clearer Understanding of Value‐Based Healthcare: A Concept Analysis
Published 2025“…The analysis also identified several crucial antecedents for transitioning traditional fee‐for‐service models to those focused on value; it also identified key interrelated consequences: improved patient outcomes, cost reduction, and increased patient satisfaction.…”
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Prevalence and clinical significance of antiphospholipid antibodies in patients with coronavirus disease 2019 admitted to intensive care units: a prospective observational study
Published 2022“…<p>Coronavirus disease 2019 (COVID-19) increases the risk of coagulopathy. Although the presence of antiphospholipid antibodies (aPLs) has been proposed as a possible mechanism of COVID-19-induced coagulopathy, its clinical significance remains uncertain. …”
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From Waste Reduction to Worker Comfort: Leveraging Lean Manufacturing and Ergonomics in Textiles Sewing Industries in UAE
Published 2024“…Lean principles are designed to identify and eliminate waste, which can result in significant productivity gains. By streamlining processes, reducing lead times, and increasing efficiency, organizations can produce more output with the same or fewer resources. …”
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