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Identifying and Assessing the Significance of Digital Twin Enablers in the Construction Industry
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A slow but steady nanoLuc: R162A mutation results in a decreased, but stable, nanoLuc activity
Published 2024“…Specifically, we performed multiple, all-atom, explicit solvent MD simulations of the apo and furimazine-docked (holo) NLuc structures revealing differential dynamics of the protein in the <u>absence</u> and presence of the ligand. …”
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Enhancing Arabic Reading Proficiency as a Second Language: Unveiling the Significance of Audiobooks for Middle School Students
Published 2024“…The integration of technology has significantly changed the landscape of foreign language education, enhancing both teaching and learning experiences. …”
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Decreased Interfacial Dynamics Caused by the N501Y Mutation in the SARS-CoV-2 S1 Spike:ACE2 Complex
Published 2022“…Additionally, we find that the N501Y mutant S1-RBD displays altered dynamics that likely aids in its enhanced interaction with ACE2. …”
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Notch Signaling Inhibition by LY411575 Attenuates Osteoblast Differentiation and Decreased Ectopic Bone Formation Capacity of Human Skeletal (Mesenchymal) Stem Cells
Published 2019“…Global gene expression profiling of LY411575-treated cells revealed changes in multiple signaling pathways, including focal adhesion, insulin, TGFβ, IL6, and Notch signaling, and decreased the expression of genes associated with functional categories of tissue development. …”
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Performance evaluation of 3D-printed PLA composites doped with WE43 magnesium alloy for bone tissue engineering applications
Published 2025“…While a low Mg content (5 %) only slightly impacted the print quality and dimensions, higher Mg concentrations (10 % and 15 %) led to increased weight, rougher surfaces, dimensional shrinkage in height, and overall poorer formation quality. Adding WE43 alloy to PLA decreased the average pore sizes of the composites. …”
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Activism, Change and Sectarianism in the Free Patriotic Movement in Lebanon
Published 2020“…It sheds light on the movement’s activism, changes and sectarianism throughout the stages of movement emergence, persistence and party transformation. …”
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Proteomics Analysis of Human Obesity Reveals the Epigenetic Factor HDAC4 as a Potential Target for Obesity
Published 2013“…In functional assays, our data indicated that ectopic expression of HDAC4 significantly impaired TNF-α-dependent activation of NF-κB, establishing thus a link between HDAC4 and regulation of the immune system. …”
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Prospective Teachers’ Levels of Scientific Literacy and Climate Change Awareness
Published 2021“…The findings of this study revealed that prospective teachers have low levels of scientific literacy, but a significant level of climate change awareness. …”
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The influence of strategic leadership and planning on the successful implementation of organizational change
Published 2011“…In today’s contemporary business world, characterized by fierce competition and uncertainty, In order to remain competitive, organization must be all set to change. Further, it is significant to note that the influence of the far environment on the organization is irresistible, as such the changes in the external and internal environment tends to dictate the need for change. …”
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Teachers’ understandings of the social and professional support needed to implement change in Qatar
Published 2022“…The Qatar National School Accreditation significantly impacted Qatar's private schools, requiring teachers to implement various mandated educational changes. …”
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Heart Rate Variability Analysis Reveals a Non-monotonic Relationship between Humanin Concentration and Cardiac Autonomic Regulation
Published 2022“…The results revealed non-monotonic relationships between measures of HRV and HN concentration. …”
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A systematic search for DNA methyltransferase polymorphisms reveals a rare DNMT3L variant associated with subtelomeric hypomethylation
Published 2009“…This analysis revealed that a rare change at DNMT3L (R271Q) was associated with significant DNA hypomethylation. …”
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