Differing endometrial expression of calcium modulating transient receptor potential channels by Maryam Ghavideldarestani (11862563)

Exosome nanovesicles as potential biomarkers and immune checkpoint signaling modulators in lung cancer microenvironment: recent advances and emerging concepts by Naushad Ahmad Khan (6406973)

Decreased Analgesic Requirements in Super Morbidly Versus Morbidly Obese Patients Undergoing Laparoscopic Sleeve Gastrectomy by Hamed Elgendy (14148846)

A slow but steady nanoLuc: R162A mutation results in a decreased, but stable, nanoLuc activity by Wesam S. Ahmed (10170053)

“…However, questions related to its mechanism of interaction with the substrate, furimazine, as well as bioluminescence activity remain elusive. Here, we combined molecular dynamics (MD) simulation and mutational analysis to show that the R162A mutation results in a decreased but stable <u>bioluminescence </u>activity of NLuc in living cells and in vitro. …”

Modulation of gut microbiota: The effects of a fruits and vegetables supplement by Arun Prasath Lakshmanan (6807152)

“…The network analysis confirmed the positive correlation between genus <i>Faecalibacterium</i> and 2-methyl butyrate. We can conclude that the FVS in healthy individuals modified the gut microbiota composition and metabolites, and it can potentially contribute to reduce the pro-inflammatory response along with the antioxidant capacity.…”

Decreased Interfacial Dynamics Caused by the N501Y Mutation in the SARS-CoV-2 S1 Spike:ACE2 Complex by Wesam S. Ahmed (10170053)

“…Additionally, we find that the N501Y mutant S1-RBD displays altered dynamics that likely aids in its enhanced interaction with ACE2. …”

L1-CAM knock-down radiosensitizes neuroblastoma IMR-32 cells by simultaneously decreasing MycN, but increasing PTEN protein expression by Rached, Johnny

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Get full text
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Both decreasing interstructural space size and increasing total cover increase shrimp abundance on artificial structures deployed in a UAE seagrass bed by Bartholomew, Aaron

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Performance evaluation of 3D-printed PLA composites doped with WE43 magnesium alloy for bone tissue engineering applications by Sumama Nuthana Kalva (17302906)

“…While a low Mg content (5 %) only slightly impacted the print quality and dimensions, higher Mg concentrations (10 % and 15 %) led to increased weight, rougher surfaces, dimensional shrinkage in height, and overall poorer formation quality. Adding WE43 alloy to PLA decreased the average pore sizes of the composites. …”

Notch Signaling Inhibition by LY411575 Attenuates Osteoblast Differentiation and Decreased Ectopic Bone Formation Capacity of Human Skeletal (Mesenchymal) Stem Cells by Nihal AlMuraikhi (6002234)

“…Among the tested molecules, LY411575, a potent γ-secretase and Notch signaling inhibitor, exhibited significant inhibitory effects on osteoblastic differentiation of hBMSCs manifested by reduced ALP activity, mineralized matrix formation, and decreased osteoblast-specific gene expression as well as in vivo ectopic bone formation. …”

Comprehensive assessment of performance and reliability of PERC, TOPCon and SHJ modules in desert climates by Maulid Kivambe (19344709)

“…Visual inspections revealed significant encapsulant delamination, occurring mostly in the first year in the SHJ modules. …”

Serum Vitamin D Concentration ≥75 nmol/L Is Related to Decreased Cardiometabolic and Inflammatory Biomarkers, Metabolic Syndrome, and Diabetes; and Increased Cardiorespiratory Fitn... by Vijay Ganji (8710491)

Computational identification of genetic subnetwork modules associated with maize defense response to Fusarium verticillioides by Mansuck Kim (19570903)

“…Based on our analysis pipeline, we identified four potential maize defense subnetwork modules. Two were directly associated with maize defense response and were associated with significant GO terms such as GO:0009817 (defense response to fungus) and GO:0009620 (response to fungus). …”

The Role of Extracellular Vesicles as Modulators of the Tumor Microenvironment, Metastasis and Drug Resistance in Colorectal Cancer by Kodappully S. Siveen (4246150)

“…This transfer influences a number of immune-related pathways leading to activation/differentiation/expression of immune cells and modulation of the tumor microenvironment that plays a significant role in CRC progression, metastasis, and drug resistance. …”

Curcumin and Derivatives in Nanoformulations with Therapeutic Potential on Colorectal Cancer by Sourour Idoudi (14153457)

“…Curcumin (CUR), extracted from Curcuma longa, has received significant attention by scientists as possible alternative to chemotherapeutic agents. …”

Energy recovery modeling of pressure-retarded osmosis systems with membrane modules compatible with high salinity draw streams by Husnain Manzoor (17115649)

“…It has been shown that the poor mass transfer behavior of a potential PRO membrane may significantly offset gains that could be realized from a high burst pressure compatible with the treatment of high-salinity draw streams. …”

Pristimerin mediated anticancer effects and sensitization of human skin cancer cells through modulation of MAPK signaling pathways by Maha Al-Tamimi (17280550)

Proteomic insight towards key modulating proteins regulated by the aryl hydrocarbon receptor involved in ovarian carcinogenesis and chemoresistance by Lubna Therachiyil (4246156)

“…We have previously reported that exposure of OC cells to TCDD, an AhR activator, significantly modulated the expression of several genes that play roles in stemness and chemoresistance. …”

Role of Exosome in Solid Cancer Progression and Its Potential Therapeutics in Cancer Treatment by Nada Aakel (18877111)

“…These vesicles activate oncogenic pathways and can serve as biomarkers or therapeutic targets due to their role in disease modulation.</p><h3>Conclusion</h3><p dir="ltr">Exosomes play a pivotal role in solid cancer progression and offer significant potential in advancing our understanding of tumor biology. …”

Beauvericin potentiates the activity of pesticides by neutralizing the ATP-binding cassette transporters in arthropods by Charbel Al Khoury (13167975)

“…Consequently, resistant pests reduce the yield of agricultural production, causing significant economic losses and reducing food security. …”