Obesity-induced changes in kidney mitochondria and endoplasmic reticulum in the presence or absence of leptin by Munusamy, Shankar

“…Renal ATP levels were decreased in both obesity models, and mitochondria isolated from both models showed alterations that would lower mitochondrial ATP production. …”
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The expression of bile acid Receptor TGR5 in Adipose Tissue in Diet-induced obesity mice by Ahmed, Sumaya

“…Total RNA was extracted from different fat depots and RT-PCR profiler array technology was used to in order to assess the mRNA expression of TGR5 and leptin. There was significant downregulation of TGR5 gene expression level in obese (DIO) mice and remarkable upregulation of TGR5 gene expression after successful weight loss in DIO mice treated with SFN in time dependent manner at 1 weeks and 4 weeks of ip applications. …”
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Adaptive effects of seeing green environment on psychophysiological parameters when walking or running by Briki W.

“…Study 2 showed that running in a green environment was associated with an increased level of perceived exertion at similar speeds (compared to other color conditions), while exposure to red induced a significant decrease in the level of tension. …”
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Evaluating the effect of glycaemic control, blood pressure, lipid profile and diabetes duration on developing diabetes complications and its progression by Albaroodi K.A.I.

“…Patients with two complications had the highest HbA1c level (8.5 ± 2%) (P=0.035). There were no significant differences in the BP and lipid profile between the groups in relation to the number of complications (P>0.05). …”
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EFFECT OF ENDOPLASMIC RETICULUM STRESS MEDIATED BY HYPERGLYCEMIA ON BARRIER FUNCTION IN RETINAL CELLS by Saif, Atiya Ramadan

“…Methodology: In the present study, utilizing the HRMEC, we evaluated the effect of high glucose (30mM) on several ER stress signaling pathway genes (HSPA5, EIF2K3, and XBP1) at the mRNA expression level; the inflammatory cytokines (NFkB) at the mRNA level; the adhesion molecules (ICAM-1 and P-selectin) by flow cytometry. …”
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Heterogeneous Diplomacy of Political Relations between Iran and Afghanistan in exploiting the water of Helmand Border River by Poorhashemi, Abbas

“…The fluctuation of the Helmand water flow and decrease in the running water towards Sistan (Iran) in the last hundred years has always created problems in relations between Iran and Afghanistan at the National and local levels. …”
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Changes in plant composition and diversity in an alpine heath and meadow after 18 years of experimental warming by Alatalo, Juha M.

“…Beta diversity increased in the meadow, while it decreased in the heath. Long-term warming had significant negative effects on the three orders of phylogenetic Hill diversity in the meadow. …”
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Towards energy efficient and quality of service aware cell zooming in 5G wireless networks by Lateef, Hafiz Yasar

“…The extensive performance evaluation of our proposed dynamic cell zooming algorithm shows that our proposed algorithm can significantly decrease both system energy consumption and outage probability.…”
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Delineating the molecular mechanisms of hippocampal neurotoxicity induced by chronic administration of synthetic cannabinoid AB-FUBINACA in mice by Ayman, Alzu'bi

“…Additionally, we showed that AB-FUBINACA significantly decreased the expression of NR1, an important functional subunit of glutamate/NMDA receptors and closely implicated in the development of toxic psychosis. …”
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The frequency of polycystic ovary syndrome in young reproductive females in Qatar by Sharif, Elham

“…Hormonal analysis demonstrated a significant increase in androgens (total testosterone, dehydroepiandrosterone sulfate, and free testosterone), and a significant decrease in sex hormone-binding globulin in our PCOS group, with a P-value ,0.05. …”
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Ethanolic extract of Origanum syriacum L. leaves exhibits potent anti-breast cancer potential and robust antioxidant properties by Mesmar, Joelle

“…Non-cytotoxic concentrations of OSEE attenuated cell proliferation and induced G0/G1 cell cycle arrest, which was associated with phosphorylation of p38 MAPK, an increase in the levels of tumor suppressor protein p21, and a decrease of proliferation marker protein Ki67. …”
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Novel potentials of the DPP-4 inhibitor sitagliptin against ischemia-reperfusion (I/R) injury in rat ex-vivo heart model by Al-Awar A.

“…NOS inhibitor (L-NAME) and TRPV-1 inhibitor (Capsazepine) were utilized to confirm the implication of both signaling mechanisms in DPP-4 inhibition-induced at the level of IS. Findings show that Sitg (50 mg) resulted in significant decrease in IS and DPP-4 activity, and significant increase in GLP-1, NOS activity, e-NOS expression, TRPV-1 level and TRPC-1 expression, compared to controls. …”
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Mixed Solid Municipal Waste-Based Biochar for Soil Fertility and Greenhouse Gas Mitigation by Bansode, Rishipal

“…On the other hand, agricultural soils have significant deficiencies in a range of essential trace elements and macronutrients and often exhibit low water holding capacity. …”
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On Time-Dependent Rheology of Sutterby Nanofluid Transport across a Rotating Cone with Anisotropic Slip Constraints and Bioconvection by Abdal, Sohaib

“…The temperature for Sutterby fluids is at a hotter level, but its velocity is vividly slower compared to those of nanofluids. …”
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Delineating the molecular mechanisms of hippocampal neurotoxicity induced by chronic administration of synthetic cannabinoid AB-FUBINACA in mice by Ayman, Alzu'bi

“…Additionally, we showed that AB-FUBINACA significantly decreased the expression of NR1, an important functional subunit of glutamate/NMDA receptors and closely implicated in the development of toxic psychosis. …”
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A lipidomic screen of hyperglycemia-treated HRECs links 12/15-Lipoxygenase to microvascular dysfunction during diabetic retinopathy via NADPH oxidase by Ibrahim, Ahmed S.

“…In the presence of arachidonic acid, additional eicosanoids generated by 12/15-LOX, including 12- and 11-HETEs, were significantly increased. Fluorescein angiography and retinal albumin leakage showed a significant decrease in retinal hyperpermeability in streptozotocin-induced diabetic mice lacking 12/15-LOX compared with diabetic WT mice. …”
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Sanguinarine suppresses growth and induces apoptosis in childhood acute lymphoblastic leukemia by Kuttikrishnan S.

“…Sang mediates its anti-cancer activity by generation of reactive oxygen species (ROS) due to depletion of glutathione level in leukemic cell lines. Pretreatment of these cells with N-acetyl cysteine (NAC) prevented Sang-induced depletion of glutathione level and mitochondrial-caspase-induced apoptosis. …”
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Boost inverter-based HVDC transmission system with inherent blocking capability of AC side contribution during DC side faults by Elserougi, A.

“…The simulation results elucidate a significant decrease in the DC fault current due to the blocking capability of the BI-HVDC system during DC side faults.…”
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Origanum syriacum L. Attenuates the Malignant Phenotype of MDA-MB231 Breast Cancer Cells by AlKahlout, Amal

“…Finally, we also show that OSE significantly inhibited angiogenesis and downregulated the level of nitric oxide (NO) production. …”
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Prophylactic antibiotics for preventing genital tract infection in women undergoing surgical procedures for incomplete abortion: a systematic review and meta-analysis of randomized... by Islam, Nazmul

“…Findings about the effect of prophylactic antibiotics in preventing genital tract infection (GTI) associated with surgical procedures used for incomplete abortions are conflicting. Some reported a decrease in infection associated with the use of antibiotic prophylaxis, while others found no significant reduction in GTI. …”
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