-
1
-
2
A slow but steady nanoLuc: R162A mutation results in a decreased, but stable, nanoLuc activity
Published 2024“…However, questions related to its mechanism of interaction with the substrate, furimazine, as well as bioluminescence activity remain elusive. Here, we combined molecular dynamics (MD) simulation and mutational analysis to show that the R162A mutation results in a decreased but stable <u>bioluminescence </u>activity of NLuc in living cells and in vitro. …”
-
3
Decreased Interfacial Dynamics Caused by the N501Y Mutation in the SARS-CoV-2 S1 Spike:ACE2 Complex
Published 2022“…Additionally, we find that the N501Y mutant S1-RBD displays altered dynamics that likely aids in its enhanced interaction with ACE2. …”
-
4
Performance evaluation of 3D-printed PLA composites doped with WE43 magnesium alloy for bone tissue engineering applications
Published 2025“…Adding WE43 alloy to PLA decreased the average pore sizes of the composites. …”
-
5
-
6
-
7
Notch Signaling Inhibition by LY411575 Attenuates Osteoblast Differentiation and Decreased Ectopic Bone Formation Capacity of Human Skeletal (Mesenchymal) Stem Cells
Published 2019“…Among the tested molecules, LY411575, a potent γ-secretase and Notch signaling inhibitor, exhibited significant inhibitory effects on osteoblastic differentiation of hBMSCs manifested by reduced ALP activity, mineralized matrix formation, and decreased osteoblast-specific gene expression as well as in vivo ectopic bone formation. …”
-
8
The Association of Hypertension with Increased Mortality Rate During the COVID-19 Pandemic: An Update with Meta-analysis
Published 2023“…Meta-regression analysis results also showed a statistically significant association between hypertension and COVID-19 mortality.…”
-
9
-
10
The Anti-Tumor Agent Sodium Selenate Decreases Methylated PP2A, Increases GSK3βY216 Phosphorylation, Including Tau Disease Epitopes and Reduces Neuronal Excitability in SHSY-5Y Neu...
Published 2019“…Somewhat surprisingly, the catalytically active form, methylated PP2A (mePP2A) was significantly decreased. In close correlation to these data, the phosphorylation state of two substrate proteins, sensitive to PP2A activity, GSK3β and Tau were found to be increased. …”
-
11
Indomethacin as a Rescue Therapy for Patent Ductus Arteriosus in Extremely Premature Infants after Failed Ibuprofen Treatment
Published 2023“…While most PDAs close after one 3-day course of either medicine, a repeat course may be necessary before considering surgical ligation for those who remain with hsPDAs. In our practice, we administer one or two courses of ibuprofen followed by a single course of indomethacin if the PDA has not shown closure or decrease in size on the echocardiogram (echo) exam. …”
-
12
Economic Statistical Design Of (X)Over-Bar Control Charts For Systems With Gamma(Lambda, 2) In-Control Times
Published 2020“…The study shows that the statistical performance of control charts can be improved significantly, with only a slight increase in the cost, by adding constraints to the optimization problem. …”
Get full text
article -
13
Economic Statistical Design Of (X)Over-Bar Control Charts For Systems With Gamma (Lambda,2) In-Control Times
Published 2020“…The study shows that the statistical performance of control charts can be improved significantly, with only a slight increase in the cost, by adding constraints to the optimization problem. …”
Get full text
article -
14
Effects of ethanol addition to diesel–biodiesel blends on the CI engine characteristics
Published 2024“…The findings show that adding biodiesel slightly affects the engine power at low and medium speeds but increases power by approximately 6% at high speeds. …”
-
15
Board changes and CEO turnover
Published 2014“…For firms that decrease independence, the CEO turnover performance sensitivity significantly decreases following SOX. …”
Get full text
Get full text
Get full text
Get full text
article -
16
IL-1 stimulates ceramide accumulation without inducing apoptosis in intestinal epithelial cells
Published 2002“…They also caused a slight but significant increase in the G2/M phase. …”
Get full text
Get full text
Get full text
article -
17
Reduced graphene aerogels as energy efficient selective oil sorbents
Published 2022“…The presence of H<sub>2</sub> significantly decreased the oxygen-containing functional groups in graphene aerogel. …”
-
18
Finite Element Modelling of FRCM-Confined RC Columns Exposed to Fire
Published 2023Get full text
doctoralThesis -
19
Investigation of Groundwater Depletion in the State of Qatar and Its Implication to Energy Water and Food Nexus
Published 2021“…Long-term temperature data indicates that the annual mean temperature increased significantly by 1.02 °C between 1987 and 2016, while total rainfall exhibited a slight decreasing trend. …”
-
20
