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The Anti-Tumor Agent Sodium Selenate Decreases Methylated PP2A, Increases GSK3βY216 Phosphorylation, Including Tau Disease Epitopes and Reduces Neuronal Excitability in SHSY-5Y Neu...
Published 2019“…Somewhat surprisingly, the catalytically active form, methylated PP2A (mePP2A) was significantly decreased. In close correlation to these data, the phosphorylation state of two substrate proteins, sensitive to PP2A activity, GSK3β and Tau were found to be increased. …”
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Identifying and Assessing the Significance of Digital Twin Enablers in the Construction Industry
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A slow but steady nanoLuc: R162A mutation results in a decreased, but stable, nanoLuc activity
Published 2024“…Here, we combined molecular dynamics (MD) simulation and mutational analysis to show that the R162A mutation results in a decreased but stable <u>bioluminescence </u>activity of NLuc in living cells and in vitro. …”
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Decreased Interfacial Dynamics Caused by the N501Y Mutation in the SARS-CoV-2 S1 Spike:ACE2 Complex
Published 2022“…In this regard, the recent SARS-CoV-2 alpha, beta, and gamma variants (B.1.1.7, B.1.351, and P.1 lineages, respectively) are of great significance in that they contain several mutations that increase their transmission rates as evident from clinical reports. …”
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Variable Selection in Data Analysis: A Synthetic Data Toolkit
Published 2024“…Variable (feature) selection plays an important role in data analysis and mathematical modeling. This paper aims to address the significant lack of formal evaluation benchmarks for feature selection algorithms (FSAs). …”
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Kefir exhibits anti‑proliferative and pro‑apoptotic effects on colon adenocarcinoma cells with no significant effects on cell migration and invasion
Published 2014“…Results from RT‑PCR showed that kefir decreases the expression of transforming growth factor α (TGF‑α); and transforming growth factor‑β1 (TGF‑β1) in HT‑29 cells. …”
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The Role of Gender in the Apology Strategies of Advanced Saudi EFL Students
Published 2017“…The purpose of this study is to examine whether gender plays a role in the apology strategies employed by 20 male and 20 female advanced Saudi EFL university students. Data were elicited using a Discourse Completion Task questionnaire (DCT), comprising of 10 real-life situations in the form of short descriptive statements which required the respondents to make an apology. …”
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Advanced Analytical and Empirical Control Strategies for Active Magnetic Bearing Systems
Published 2025“…The work focuses on emphasizing advanced control strategies using Fourier and empirical data-driven engineering approaches, which have significantly expanded the potential applications of AMB across various industries. …”
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Artificial Intelligence in rehabilitation: A narrative review on advancing patient care
Published 2025“…Evidence from current literature highlights how AI improves patient satisfaction, engagement, and clinical outcomes by fostering a stronger therapeutic alliance and promoting adherence to treatment plans. However, significant challenges remain, including data privacy concerns, clinician training gaps, and disparities in technology access. …”
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The relationships between training, emotional intelligence and structural career advancement. (c2016)
Published 2016“…Purpose – The unquenchable thirst for career advancement puts researchers to work to uncover the “recipe” for progressing in the corporate jungle. …”
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Daucus carota pentane-based fractions arrest the cell cycle and increase apoptosis in MDA-MB-231 breast cancer cells
Published 2014“…The increase in apoptosis in response to treatment was also apparent in the increase in BAX and the decrease in Bcl-2 levels as well as the proteolytic cleavage of both caspase-3 and PARP as revealed by Western blot. …”
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Advancing paleontology: a survey on deep learning methodologies in fossil image analysis
Published 2025“…Finally, we discuss novel techniques for fossil data augmentation and fossil image enhancements, which can be combined with advanced neural network architectures, such as diffusion models, generative hybrid networks, transformers, and graph neural networks, to improve body fossil image analysis.…”