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A slow but steady nanoLuc: R162A mutation results in a decreased, but stable, nanoLuc activity
Published 2024“…However, questions related to its mechanism of interaction with the substrate, furimazine, as well as bioluminescence activity remain elusive. Here, we combined molecular dynamics (MD) simulation and mutational analysis to show that the R162A mutation results in a decreased but stable <u>bioluminescence </u>activity of NLuc in living cells and in vitro. …”
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Decreased Interfacial Dynamics Caused by the N501Y Mutation in the SARS-CoV-2 S1 Spike:ACE2 Complex
Published 2022“…</p><p dir="ltr">Corrigendum: Decreased interfacial dynamics caused by the N501Y mutation in the SARS-CoV-2 S1 spike:ACE2 complex: Frontiers in Molecular Biosciences: <a href="https://dx.doi.org/10.3389/fmolb.2022.1018464" rel="noreferrer" target="_blank">https://dx.doi.org/10.3389/fmolb.2022.1018464</a>, published online 19 October 2022.…”
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Notch Signaling Inhibition by LY411575 Attenuates Osteoblast Differentiation and Decreased Ectopic Bone Formation Capacity of Human Skeletal (Mesenchymal) Stem Cells
Published 2019“…Among the tested molecules, LY411575, a potent γ-secretase and Notch signaling inhibitor, exhibited significant inhibitory effects on osteoblastic differentiation of hBMSCs manifested by reduced ALP activity, mineralized matrix formation, and decreased osteoblast-specific gene expression as well as in vivo ectopic bone formation. …”
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The Anti-Tumor Agent Sodium Selenate Decreases Methylated PP2A, Increases GSK3βY216 Phosphorylation, Including Tau Disease Epitopes and Reduces Neuronal Excitability in SHSY-5Y Neu...
Published 2019“…Somewhat surprisingly, the catalytically active form, methylated PP2A (mePP2A) was significantly decreased. In close correlation to these data, the phosphorylation state of two substrate proteins, sensitive to PP2A activity, GSK3β and Tau were found to be increased. …”
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Special Issue: Empowering eHealth with Smart Internet of Things (IoT) Medical Devices
Published 2019“…In such an environment, the patient’s vital parameters are transmitted by medical devices onto secure cloud based platforms where they are stored, aggregated and analyzed. …”
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Prioritizing the multi-criterial features based on comparative approaches for enhancing security of IoT devices
Published 2023“…This research highlights the authentication feature of IoT devices from literature studies and evaluates the significant feature using COPRAS approach to assist organization in enhancing security of IoT devices.…”
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Prioritizing the multi-criterial features based on comparative approaches for enhancing security of IoT devices
Published 2023“…This research highlights the authentication feature of IoT devices from literature studies and evaluates the significant feature using COPRAS approach to assist organization in enhancing security of IoT devices.…”
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A Features-Based Privacy Preserving Assessment Model for Authentication of Internet of Medical Things (IoMT) Devices in Healthcare
Published 2023“…<p dir="ltr">Internet of Things (IoT) devices have drawn significant attention over the last few years due to their significant contribution to every domain of life, but the major application of these devices has been witnessed in the healthcare sector. …”
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Characterization of the dynamic flow response in microfluidic devices
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Simultaneous Multi-Adulterant Detection in Milk Using an In-house Developed Multiplexed Microfluidic Paper-Based Analytical Device (M-µPAD)
Published 2025“…This study introduces a multiplexed microfluidic paper-based analytical device (M-µPAD) for rapid and simultaneous detection of multiple milk adulterants. …”
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Energy-aware adaptive compression for mobile devices. (c2009)
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Security Assessment of Low-Resource Edge Devices for IoT Systems
Published 2020Get full text
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Indomethacin as a Rescue Therapy for Patent Ductus Arteriosus in Extremely Premature Infants after Failed Ibuprofen Treatment
Published 2023“…In our practice, we administer one or two courses of ibuprofen followed by a single course of indomethacin if the PDA has not shown closure or decrease in size on the echocardiogram (echo) exam. …”