Targeted Inactivation of Rin3 Increases Trabecular Bone Mass by Reducing Bone Resorption and Favouring Bone Formation by Mahéva Vallet (18456729)

“…<p dir="ltr">Common genetic variants at the RIN3 locus on chromosome 14q32 predispose to Paget’s disease of bone (PDB) but the mechanisms by which they do so are unknown. …”

Increased levels of CSF total but not oligomeric or phosphorylated forms of alpha-synuclein in patients diagnosed with probable Alzheimer’s disease by Nour K. Majbour (8809316)

“…CSF total α-syn (t-α-syn) significantly increased in the AD group (p < 0.0001) compared to controls, while oligomeric- and phosphorylated-Ser129-α-syn did not change significantly. …”

Prevalence and clinical significance of antiphospholipid antibodies in patients with coronavirus disease 2019 admitted to intensive care units: a prospective observational study by Mostafa Najim (14150400)

“…<p>Coronavirus disease 2019 (COVID-19) increases the risk of coagulopathy. …”

The Association of Hypertension with Increased Mortality Rate During the COVID-19 Pandemic: An Update with Meta-analysis by Ahmad R. Al-Qudimat (17337808)

Cardiac phosphodiesterases are differentially increased in diabetic cardiomyopathy by Hanna, Rita

“…However, β2-AR receptors expression remained unchanged regardless of the disease stage. Moreover, we noted an early and specific upregulation of cardiac PDE1A, PDE2A, PDE4B, PDE4D and PDE5A expression at week 4, followed by increases in PDE3A levels in diabetic hearts at week 8. …”
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Serum Vitamin D Concentration ≥75 nmol/L Is Related to Decreased Cardiometabolic and Inflammatory Biomarkers, Metabolic Syndrome, and Diabetes; and Increased Cardiorespiratory Fitn... by Vijay Ganji (8710491)

Surgical Management of Hepatic Benign Disease: Have the Number of Liver Resections Increased in the Era of Minimally Invasive Approach? Analysis from the I Go MILS (Italian Group o... by Ardito, Francesco

“…A time-trend analysis showed that the total number of MILS and the number of MILS for malignant disease significantly increased, but this increasing trend was not documented for the number of MILS for BD, which remained stable during the study period of time. …”
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The Anti-Tumor Agent Sodium Selenate Decreases Methylated PP2A, Increases GSK3βY216 Phosphorylation, Including Tau Disease Epitopes and Reduces Neuronal Excitability in SHSY-5Y Neu... by Wesal Habbab (17346961)

Association of coronary artery disease and chronic kidney disease in Lebanese population by Milane, Aline

“…This correlation remained highly significant despite considerable inter-patient variability and was at its highest at the most advanced stages of both diseases. …”
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Stemming cardiovascular diseases in Qatar by Nature Research (16552612)

“…This is projected to increase to more than 23 million by 2030, with the largest increase to occur throughout the Middle East, due in part to the adoption of the sedentary Western lifestyle.…”

Epigenetic analysis of Paget’s disease of bone identifies differentially methylated loci that predict disease status by Ilhame Diboun (3522413)

“…<p dir="ltr">Paget’s disease of bone (PDB) is characterized by focal increases in disorganized bone remodeling. …”

Aorta deformation linked to heart disease by Nature Research (16552612)

“…Normally this stiffening is associated with increased morbidity in patients with hypertension, diabetes, and end-stage kidney disease, but whether this is also true of HCM is still not clear. …”

Mixed precision iterative refinement with adaptive precision sparse approximate inverse preconditioning by Noaman Khan (19810050)

“…<p dir="ltr">Hardware trends have motivated the development of mixed precision algorithms in numerical linear algebra, which aim to decrease runtime while maintaining acceptable accuracy. …”

Aortic stiffness, kidney disease, and renal transplantation by Bahous, Sola Aoun

“…In renal transplant patients, aortic stiffness is significantly increased irrespective of donor type. Donor age and/or acute rejection contribute independently to the increased stiffness. …”
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Auto-immunoproteomics analysis of COVID-19 ICU patients revealed increased levels of autoantibodies related to the male reproductive system by Frank Schmidt (207186)

Inflammatory Markers and COVID-19 Disease Progression by Santosh Kumar Sidhwani (16488557)

“…All markers, except procalcitonin, demonstrated a significant correlation with disease severity. These results could enhance our understanding of COVID-19 pathogenesis and help predict and manage severe cases.…”

Dietary patterns in cardiovascular diseases prevention and management by Dimassi, Hani

“…The significance of this type of research to primary care physicians is also highlighted. …”
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Effect of fasting on laryngopharyngeal reflux disease in male subjects by Hamdan, Abdul-Latif

“…Fasting results in a nonsignificant increase in laryngopharyngeal reflux disease. The increase can be hypothetically explained on the change in eating habits and the known alterations in gastric secretions during Ramadan. …”
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The effect of self-reported flossing behavior on cardiovascular disease events and mortality Findings from the 2009-2016 National Health and Nutrition Examination Surveys by Nebu, Philip

“…BackgroundThere is increasing evidence suggesting that daily oral hygiene self-care measures may alleviate cardiovascular disease (CVD) risk. …”
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Global Burden of Cardiovascular Diseases and Risk Factors, 1990–2019 by Gregory A. Roth (6302315)

“…The global trends for disability-adjusted life years (DALYs) and years of life lost also increased significantly, and years lived with disability doubled from 17.7 million (95% UI: 12.9 to 22.5 million) to 34.4 million (95% UI:24.9 to 43.6 million) over that period. …”