A slow but steady nanoLuc: R162A mutation results in a decreased, but stable, nanoLuc activity by Wesam S. Ahmed (10170053)

“…In this regard, engineering of brighter bioluminescent proteins, i.e. luciferases, has played a significant role. This is acutely exemplified by the engineering of the NLuc <u>luciferase</u>, which is small in size and displays much enhanced bioluminescence and<u> thermal stability</u> compared to previously available luciferases. …”

Decreased Interfacial Dynamics Caused by the N501Y Mutation in the SARS-CoV-2 S1 Spike:ACE2 Complex by Wesam S. Ahmed (10170053)

“…<p dir="ltr">Coronavirus Disease of 2019 (COVID-19) caused by Severe Acute Respiratory Syndrome Coronavirus 2 (SARS-CoV-2) has resulted in a massive health crisis across the globe, with some genetic variants gaining enhanced infectivity and competitive fitness, and thus significantly aggravating the global health concern. …”

Use of Ultrasound and Ionic Liquids to Enhance the Extractive Desulfurization of Oils by Zuraiqi, Karma

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Dihydromyricetin and Salvianolic acid B inhibit alpha-synuclein aggregation and enhance chaperone-mediated autophagy by Jia-Zhen Wu (6844793)

“…Cells were co-transfected with a C-terminal modified α-synuclein (SynT) and synphilin-1, and then treated with DHM (10 μM) and Sal B (50 μM) 16 hours after transfection; levels of α-synuclein aggregation decreased significantly (68% for DHM and 75% for Sal B). …”

The Anti-Tumor Agent Sodium Selenate Decreases Methylated PP2A, Increases GSK3βY216 Phosphorylation, Including Tau Disease Epitopes and Reduces Neuronal Excitability in SHSY-5Y Neu... by Wesal Habbab (17346961)

“…Somewhat surprisingly, the catalytically active form, methylated PP2A (mePP2A) was significantly decreased. In close correlation to these data, the phosphorylation state of two substrate proteins, sensitive to PP2A activity, GSK3β and Tau were found to be increased. …”

Numerical Modeling of Sequential Segmentation for Enhancement of Mixing Inside Microchannels by Abu Dagga, Ibragim

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Brain Connectivity Analysis Under Semantic Vigilance and Enhanced Mental States by Yahya, Fares

“…BRMUS factors, such as fatigue, depression, and anger, significantly decrease in the enhancement group compared to vigilance group. …”
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Functional Connectivity Analysis under Vigilance Decrement and Enhanced Mental States by Hassanin, Omnia

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Enhancing Thermal Comfort for the Revitalization of Pedestrian-Friendly Shopping Arcades in Dubai, UAE by RAJEEV, ANN MARIA

“…Using ENVI-met software, simulations are conducted in three stages: urban materials, building facade materials, and vegetation and landscaping, encompassing thirteen different combinations to examine four key aspects: temperature, humidity, wind speed, and PMV value, which significantly affect outdoor thermal comfort. The most favorable cases are selected from each phase, and the final reduction in temperature and PMV values of the optimized case indicates a substantial decrease of 3.76 degrees Celsius in air temperature post-implementation of passive design strategies. …”
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Small molecule inhibition of stat3 enhances survival in mice with intracerebral melanoma by Abou-Ghazal, Mohamed

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Enhanced glucose uptake in phenylbutyric acid-treated 3T3-L1 adipocytes by Fakhoury, H.

“…The expression of PIP3 and pAkt increased indicating enhanced PI3k pathway activity. There was a significant decrease in PTEN activity as evident by a rise in the phosphorylated form of this protein. …”
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Heat transfer measurements of Polyalpha-Olefin- boron nitride nanofluids for thermal management and lubrication applications by Ahmad K. Sleiti (14778229)

“…Two competing phenomena affect the heat transfer performance: the increase/decrease in resistance to thermal diffusion sublayer when thermal conductivity increases and viscosity decreases, respectively. …”

Andrographolide pre-treatment enhances the anti-tumor activity of topotecan on acute myeloid leukemia cells in vitro by Rizk, Sandra

“…Cotreating the cells with both topotecan and andrographolide simultaneously at various concentrations did not result in any significant changes. However, pretreating the cells with andrographolide for 24 hours prior to topotecan addition, led to a significant decrease in cell proliferation (39%) as compared to treatment with the compounds separately (67%). …”
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Global, regional, and national progress towards Sustainable Development Goal 3.2 for neonatal and child health: all-cause and cause-specific mortality findings from the Global Burd... by Katherine R Paulson (8674293)

“…</p><p><br></p><h3>Findings</h3><p dir="ltr">Global U5MR decreased from 71·2 deaths per 1000 livebirths (95% uncertainty interval [UI] 68·3–74·0) in 2000 to 37·1 (33·2–41·7) in 2019 while global NMR correspondingly declined more slowly from 28·0 deaths per 1000 live births (26·8–29·5) in 2000 to 17·9 (16·3–19·8) in 2019. …”

An Improved Genghis Khan Optimizer based on Enhanced Solution Quality Strategy for Global Optimization and Feature Selection Problems by Abdel-Salam, Mahmoud

“…The primary goals of feature selection are to decrease the number of dimensions and enhance classification accuracy in many domains, such as text classification, large-scale data analysis, and pattern recognition. …”
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Physical Exercise Enhanced Heat Shock Protein 60 Expression and Attenuated Inflammation in the Adipose Tissue of Human Diabetic Obese by Abdelkrim Khadir (437074)

Myeloid Cells in Circulation and Tumor Microenvironment of Colorectal Cancer Patients with Early and Advanced Disease Stages by Salman M. Toor (8854751)

“…We found high levels of granulocytic myeloid cells (GMCs) in whole blood, but their levels were significantly lower in PBMCs. Importantly, we found significantly higher levels of GMCs in the TME compared to NT. …”

Methane production enhancement from Tetraselmis biomass co-digestion using frying oil residue as co-substrate and ultrasonication as pretreatment by Firas, Feki

“…Tetraselmis sp. microalgae biomass co-digestion with frying oil residue was investigated without or with an ultrasonication pretreatment to enhance methane production. Interestingly, compared to untreated Tetraselmis biomass, sonication pretreatment using specific energy of 1.6 kJ/g VS significantly improved specific methane production by 60.5%. …”
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Accelerating Care: Enhancing Patient Satisfaction through a Quality Initiative in the Obstetrics and Gynaecology Emergency Department at Al Wakra Hospital, Qatar by Lolwa Al Ansari (18466227)

“…</p><h3>Results</h3><p dir="ltr">The strategies implemented significantly reduced waiting times, enhancing both patient care and operational efficiency. …”

Phosphate-solubilizing bacteria-mediated rock phosphate utilization with poultry manure enhances soil nutrient dynamics and maize growth in semi-arid soil by Kashif Khan (2978691)

“…The integration of RP and PM, particularly with PSB inoculation, significantly (p < 0.05) improved soil and plant nitrogen (N), phosphorus (P), and potassium (K) levels. …”