The Anti-Tumor Agent Sodium Selenate Decreases Methylated PP2A, Increases GSK3βY216 Phosphorylation, Including Tau Disease Epitopes and Reduces Neuronal Excitability in SHSY-5Y Neu... by Wesal Habbab (17346961)

“…Somewhat surprisingly, the catalytically active form, methylated PP2A (mePP2A) was significantly decreased. In close correlation to these data, the phosphorylation state of two substrate proteins, sensitive to PP2A activity, GSK3β and Tau were found to be increased. …”

Addition of sphingosine-1-phosphate to human oocyte culture medium decreases embryo fragmentation by Zreik, Tony

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Decreased Analgesic Requirements in Super Morbidly Versus Morbidly Obese Patients Undergoing Laparoscopic Sleeve Gastrectomy by Hamed Elgendy (14148846)

A slow but steady nanoLuc: R162A mutation results in a decreased, but stable, nanoLuc activity by Wesam S. Ahmed (10170053)

“…In this regard, engineering of brighter bioluminescent proteins, i.e. luciferases, has played a significant role. This is acutely exemplified by the engineering of the NLuc <u>luciferase</u>, which is small in size and displays much enhanced bioluminescence and<u> thermal stability</u> compared to previously available luciferases. …”

Decreased Interfacial Dynamics Caused by the N501Y Mutation in the SARS-CoV-2 S1 Spike:ACE2 Complex by Wesam S. Ahmed (10170053)

“…<p dir="ltr">Coronavirus Disease of 2019 (COVID-19) caused by Severe Acute Respiratory Syndrome Coronavirus 2 (SARS-CoV-2) has resulted in a massive health crisis across the globe, with some genetic variants gaining enhanced infectivity and competitive fitness, and thus significantly aggravating the global health concern. …”

Reduced graphene aerogels as energy efficient selective oil sorbents by Junaid Saleem (14670322)

“…The presence of H₂ significantly decreased the oxygen-containing functional groups in graphene aerogel. …”

Notch Signaling Inhibition by LY411575 Attenuates Osteoblast Differentiation and Decreased Ectopic Bone Formation Capacity of Human Skeletal (Mesenchymal) Stem Cells by Nihal AlMuraikhi (6002234)

“…Among the tested molecules, LY411575, a potent γ-secretase and Notch signaling inhibitor, exhibited significant inhibitory effects on osteoblastic differentiation of hBMSCs manifested by reduced ALP activity, mineralized matrix formation, and decreased osteoblast-specific gene expression as well as in vivo ectopic bone formation. …”

Ecotoxicological Assessment of Thermally- and Hydrogen-Reduced Graphene Oxide/TiO₂ Photocatalytic Nanocomposites Using the Zebrafish Embryo Model by Halema Al-Kandari (6316961)

“…However, both nanocomposites should be used with caution at concentration higher than the NOEC (400 mg/L), in particular RGOTi, which significantly (i) caused pericardial and yolk sac edema; (ii) decreased the hatching rate, locomotion, and hematopoietic activities; and (iii) affected the heart rate. …”

Two-surgeon technique of parenchymal transection contributes to reduced transfusion rate in patients undergoing major hepatectomy by Palavecino, Martin

“…Although transfusion rates can be reduced to almost 0 in uncomplicated hepatectomies, the blood transfusion rates associated with liver resection remain significant at tertiary referral centers, such as ours. …”
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Reversal of memory and neuropsychiatric symptoms and reduced tau pathology by selenium in 3xTg-AD mice by Ann Van der Jeugd (18629695)

“…Chronic sodium selenate treatment efficiently reversed hippocampal-dependent learning and memory impairments, and behavior- and neuropsychiatric-like symptoms in old female 3xTg-AD mice. Selenium significantly decreased the number of aggregated tau-positive neurons and astrogliosis, without globally affecting amyloid plaques, in the hippocampus of 3xTg-AD mice. …”

An imageable retinoid acid derivative to detect human cancer xenografts and study therapeutic dosing to reduce its toxicity by Wang, Wei

“…In addition, retinoic acid can reverse premalignancy, significantly decrease second primary tumors and provide a treatment benefit in head and neck, lung, esophagus, colon and bladder cancer. …”
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Use of Ultrasound and Ionic Liquids to Enhance the Extractive Desulfurization of Oils by Zuraiqi, Karma

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Brain Connectivity Analysis Under Semantic Vigilance and Enhanced Mental States by Yahya, Fares

“…BRMUS factors, such as fatigue, depression, and anger, significantly decrease in the enhancement group compared to vigilance group. …”
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Numerical Modeling of Sequential Segmentation for Enhancement of Mixing Inside Microchannels by Abu Dagga, Ibragim

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Functional Connectivity Analysis under Vigilance Decrement and Enhanced Mental States by Hassanin, Omnia

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An Improved Genghis Khan Optimizer based on Enhanced Solution Quality Strategy for Global Optimization and Feature Selection Problems by Abdel-Salam, Mahmoud

“…The primary goals of feature selection are to decrease the number of dimensions and enhance classification accuracy in many domains, such as text classification, large-scale data analysis, and pattern recognition. …”
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Enhancing Thermal Comfort for the Revitalization of Pedestrian-Friendly Shopping Arcades in Dubai, UAE by RAJEEV, ANN MARIA

“…Using ENVI-met software, simulations are conducted in three stages: urban materials, building facade materials, and vegetation and landscaping, encompassing thirteen different combinations to examine four key aspects: temperature, humidity, wind speed, and PMV value, which significantly affect outdoor thermal comfort. The most favorable cases are selected from each phase, and the final reduction in temperature and PMV values of the optimized case indicates a substantial decrease of 3.76 degrees Celsius in air temperature post-implementation of passive design strategies. …”
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A lipidomic screen of hyperglycemia-treated HRECs links 12/15-Lipoxygenase to microvascular dysfunction during diabetic retinopathy via NADPH oxidase by Ahmed S. Ibrahim (10049522)

“…The permeability effect of 12-HETE was significantly reduced in NOX2^−/− mice compared with the WT mice. …”

Hedgehog Signaling Inhibition by Smoothened Antagonist BMS-833923 Reduces Osteoblast Differentiation and Ectopic Bone Formation of Human Skeletal (Mesenchymal) Stem Cells by Nihal AlMuraikhi (6002234)

Small molecule inhibition of stat3 enhances survival in mice with intracerebral melanoma by Abou-Ghazal, Mohamed

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