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Notch Signaling Inhibition by LY411575 Attenuates Osteoblast Differentiation and Decreased Ectopic Bone Formation Capacity of Human Skeletal (Mesenchymal) Stem Cells
Published 2019“…Among the tested molecules, LY411575, a potent γ-secretase and Notch signaling inhibitor, exhibited significant inhibitory effects on osteoblastic differentiation of hBMSCs manifested by reduced ALP activity, mineralized matrix formation, and decreased osteoblast-specific gene expression as well as in vivo ectopic bone formation. …”
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A slow but steady nanoLuc: R162A mutation results in a decreased, but stable, nanoLuc activity
Published 2024“…In this regard, engineering of brighter bioluminescent proteins, i.e. luciferases, has played a significant role. This is acutely exemplified by the engineering of the NLuc <u>luciferase</u>, which is small in size and displays much enhanced bioluminescence and<u> thermal stability</u> compared to previously available luciferases. …”
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Small molecule inhibition of stat3 enhances survival in mice with intracerebral melanoma
Published 2008Get full text
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Suppression of Unstable Flow by Using Rough Surfaces at Small Mass Flow Rates in a Radial Diffuser
Published 2006Get full text
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Optimizing the number of players and training bout durations in soccer small‐sided games: Effects on mood balance and technical performance
Published 2025“…Therefore, coaches should consider longer continuous bouts when planning SSGs‐based training to significantly decrease TMD and enhance technical‐tactical performance in soccer SSGs.…”
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YOLO-DefXpert: An Advanced Defect Detection on PCB Surfaces Using Improved YOLOv11 Algorithm
Published 2025“…Accurately identifying small defects on PCB surfaces remains a considerable challenge, particularly under complex background conditions, due to the intricate and compact layout of the boards. …”
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An Analysis of Thermal Comfort at the School Outdoor Spaces: A Case Study of the American School of Creative Science, Dubai, UAE
Published 2022“…Additionally, the addition of vegetation alone had an impact on the microclimate decreasing it by 5%. Thus, combining the strategies of vegetation, shade, green facades/roofs and small water features resulted in 5% to 25% reduction in PET depending on the corresponding location being analyzed. …”
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A High‐Performance MPPT Solution for Solar DC Microgrids: Leveraging the Hippopotamus Algorithm for Greater Efficiency and Stability
Published 2025“…<p dir="ltr">The rapid growth of modern civilization has led to increased global warming and climate challenges. Variations in atmospheric temperature, sunlight intensity and other factors significantly impact the performance of photovoltaic (PV) systems. …”
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Preparation of albumin-targeted liposomes and the study of their release characteristics using ultrasound
Published 2016Get full text
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Past, present and future global mangrove primary productivity
Published 2024“…However, significant regional changes were identified, including substantial increases in NPP in the Southwest Australian Shelf (60.58 ± 97.9 %), the Warm Temperate Northeast Pacific (43.75 ± 65.7 %), and the Warm Temperate Northwest Pacific (31.55 ± 55.7 %), as well as decreases in <u>Southeast Asian </u>provinces like the Java Transitional (11.45 ± 6.2 %) and Western Coral Triangle (7.61 ± 9.6 %). …”
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Burst Round Robin as a Proportional-Share Scheduling Algorithm
Published 2020“…This will reduce the number of processes in the ready queue by knocking out short jobs relatively faster in a hope to increase the throughput and reduce the average waiting time.…”
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Characterization and Modeling of Damage in Steel at Different Strain Rates
Published 2011Get full text
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Effects of ethanol addition to diesel–biodiesel blends on the CI engine characteristics
Published 2024“…Thermal efficiency shows a reverse behaviour, with a small negative impact of ethanol addition. Biodiesel addition significantly increases carbon monoxide (CO) emissions, reaching an average of 190% across all speeds. …”
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The protective role of lidocaine in surgeries involving trigeminal nerve manipulation: a meta-analysis of trigeminocardiac reflex prevention
Published 2025“…Additionally, the lidocaine group had a relatively small change in HR, with a mean difference of -10.56 (95% CI -13.30 to -7.83 beat per minute, <i>P</i> = 0.00001). …”