The posterior pole and papillomacular fold in posterior microphthalmos by Nowilaty, Sawsan R.

“…Conclusions The PMF in PM eyes has characteristic morphologic SD-OCT features. The increased posterior pole curvature in PM and its significant correlation with the axial length, the PMF severity and keratometry established in this study suggest that PM eyes are not only shorter than normal, but seem to be abnormally shaped posteriorly, particularly along the vertical meridian. …”
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Complete resection of the alar folds in eight standing horses with a bipolar dividing and vessel‐sealing device by Airina Kallmyr (18622924)

“…Median earnings post‐surgery increased (P = .03) compared with pre‐surgery.</p> <h3>Conclusion</h3> <p>Alar fold resection with bipolar electrosurgical energy offered a good alternative to the traditional surgical approaches performed under general anesthesia. …”

Photoactivatable RuII Complex Bearing 2,9‐Diphenyl‐1,10‐phenanthroline: Unusual Photochemistry and Significant Potency on Cisplatin‐Resistant Cell Lines by Mansour, Najwa

“…Complex 1 demonstrated only marginal activity in the dark; its cytotoxicity increased significantly upon photoactivation with a high phototoxicity index (PI = [IC50 dark]/[IC50 light]) ranging from 39.2‐fold in A549 to over 100‐fold in MDA‐MB‐231. …”
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Auto-immunoproteomics analysis of COVID-19 ICU patients revealed increased levels of autoantibodies related to the male reproductive system by Frank Schmidt (207186)

In vivo immunomodulatory effect of wild carrot oil and its fractions by Taleb, RI

“…Whereas, DCOE and F1 did not induce a significant increase in IFN-γ levels at either interval, F2, F3, F4 and LPS caused 6.7, 4.6, 3.5 and 2.3 fold increases, respectively. …”
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The molecular mechanisms of apoptosis accompanied with the epigenetic regulation of the NY-ESO-1 antigen in non-small lung cancer cells treated with decitabine (5-aza-CdR) by Varghese P. Inchakalody (14557382)

“…Bisulfite-sequencing demonstrated 45.6% demethylation efficiency at the NY-ESO-1 gene promoter region and RT-qPCR analysis confirmed the significant induction of NY-ESO-1 at mRNA level (128-fold increase, *p < 0.050). …”

Methylation at global LINE-1 repeats in human blood are affected by gender but not by age or natural hormone cycles by El Maarri, Osman

“…Previously, we reported on inter-individual and gender specific variations of LINE-1 methylation in healthy individuals. …”
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Treatment with decitabine induces the expression of stemness markers, PD-L1 and NY-ESO-1 in colorectal cancer: potential for combined chemoimmunotherapy by Nassiba Taib (14557385)

“…</p><h2>Results</h2><p dir="ltr">DAC treatment significantly upregulated stemness markers in both primary 1076 Col and meta-static 1872 Col cell lines, although a lower effect occurred on the latter: CD44 (7.85 fold; ***p = 0.0001 vs. (4.19 fold; *p = 0.0120), Nanog (4.1 fold; ***p < 0.0001 vs.1.69 fold; ***p = 0.0008), KLF-4 (4.33 fold; ***p < 0.0001 vs.2.48 fold; ***p = 0.0005), CD133 (16.77 fold; ***p = 0.0003 vs.6.36 fold; *p = 0.0166), and MSI-1 (2.33 fold; ***p = 0.0003 vs.2.3 fold; ***p = 0.0004), respectively. …”

Gasoline fume inhalation induces apoptosis, inflammation, and favors Th2 polarization in C57BL/6 mice by Nour-Eldine, Wared

“…Interestingly, IL-10 expression was also increased by ~ 10-fold in the lungs of GE mice suggesting an attempt to counterbalance the established inflammation. …”
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Cadmium-induced endothelial dysfunction mediated by asymmetric dimethylarginine by Hamda A. Al-Naemi (14151675)

“…Interestingly, the expression of eNOS in the Cd-treated group was found to be significantly elevated during the exposure by more than 3-fold in comparison with that in the control group. …”

Host Genetic Variants Potentially Associated With SARS-CoV-2: A Multi-Population Analysis by Maria K. Smatti (4675852)

“…Remarkably, Africans seem to carry extremely lower frequencies of SARS-CoV-1 susceptibility alleles, reaching to 32-fold decrease compared to other populations.</p><h3>Conclusion</h3><p dir="ltr">Multiple genetic variants, which could potentially modulate SARS-CoV-2 infection, are significantly variable between populations, with the lowest frequency observed among Africans. …”

Adipocyte Enhancer-Binding Protein 1 (AEBP1) (a Novel Macrophage Proinflammatory Mediator) Overexpression Promotes and Ablation Attenuates Atherosclerosis in ApoE⁻′⁻ and LDLR⁻′⁻ Mi... by Bogachev, Oleg

“…Consistently, ablation of AEBP₁ results in significant attenuation of atherosclerosis (males: 3.2-fold, P = 0.001 (en face)), 2.7-fold, P = 0.0004 (aortic roots); females: 2.1-fold, P = 0.0026 (en face), 1.7-fold, P = 0.0126 (aortic roots)) in the AEBP₁⁻′⁻/low-density lipoprotein receptor (LDLR)⁻′⁻ double-knockout (KO) mice. …”
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Qatar’s immigrants at higher risk of diabetes by Nature Research (16552612)

“…Those of South Asian descent had a 13-fold increased risk of having elevated glycated haemoglobin levels, and Filipinos a 4.5-fold increase, compared to the native Arab population. …”

Effect of temperature on the rheological properties of neat aqueous Wyoming sodium bentonite dispersions by Vryzas, Zisis

“…The Herschel-Bulkley rheological model fitted extremely well all data. The yield stress increased linearly with temperature by almost three-fold, the flow consistency index decreased exponentially with temperature by almost five-fold and the flow behavior index increased by about 20%, tending towards the Newtonian value. …”
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Changes in growth patterns due to nutritional adjustment in children of Northeast Brazil by Carlos A Bruno da Silva (19772745)

“…Body mass index increased throughout follow-up. Arm muscle area and tricipital skin fold increased significantly during the follow-up period.…”

Association Between Hypothyroidism and Hepatocellular Carcinoma: A Case-Control Study in the United States by Hassan, Manal M.

“…Restricted analyses among hepatitis virus–negative subjects, nondrinkers, nondiabetics, nonsmokers, and nonobese individuals indicated a significant association between hypothyroidism and HCC, with an approximate two-fold to three-fold increased risk of HCC development. …”
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Vocal Changes in Patients With Polycystic Ovary Syndrome by Hannoun, Antoine

“…There was no statistically significant difference in the acoustic parameters except for an increase in the relative average perturbation (P value = 0.035) and a decrease in maximum phonation time (P value = 0.001) in patients with PCOS. …”
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A lipidomic screen of hyperglycemia-treated HRECs links 12/15-Lipoxygenase to microvascular dysfunction during diabetic retinopathy via NADPH oxidase by Ahmed S. Ibrahim (10049522)

“…LC/MS lipidomic screen of human retinal endothelial cells (HRECs) demonstrated that 15-HETE was the only significantly increased metabolite (2.4 ± 0.4-fold, <i>P</i> = 0.0004) by high glucose (30 mM) treatment. …”

Enhanced cellular uptake and photochemotherapeutic potential of a lipophilic strained Ru(II) polypyridyl complex by Mehanna, Stephanie

“…Cellular uptake of complex 1 and the free BC ligand were found to be significantly facilitated as evidenced by 400–600 fold increase in concentration of the compounds inside the cells relative to the extracellular culture medium. …”
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Open access of evidence‐based publications by Yammine, Kaissar

“…We demonstrated that despite a 10‐fold increase in the number of evidence‐based publications in the past 10 years, the rate of free systematic reviews in the general biomedical literature did not change for the last two decades. …”
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