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The Anti-Tumor Agent Sodium Selenate Decreases Methylated PP2A, Increases GSK3βY216 Phosphorylation, Including Tau Disease Epitopes and Reduces Neuronal Excitability in SHSY-5Y Neu...
Published 2019“…Somewhat surprisingly, the catalytically active form, methylated PP2A (mePP2A) was significantly decreased. In close correlation to these data, the phosphorylation state of two substrate proteins, sensitive to PP2A activity, GSK3β and Tau were found to be increased. …”
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A slow but steady nanoLuc: R162A mutation results in a decreased, but stable, nanoLuc activity
Published 2024“…Here, we combined molecular dynamics (MD) simulation and mutational analysis to show that the R162A mutation results in a decreased but stable <u>bioluminescence </u>activity of NLuc in living cells and in vitro. …”
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Student learning in higher education through blogging in the classroom
Published 2019“…It was found that students do perceive higher degrees of learning from using blogs, but the recognised benefits of using blogs is influenced by the students’ attitudes towards the use of technology in teaching and learning, their perceived usefulness of blogs, and the extent to which they have used blogs previously. …”
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Decreased Interfacial Dynamics Caused by the N501Y Mutation in the SARS-CoV-2 S1 Spike:ACE2 Complex
Published 2022“…In this regard, the recent SARS-CoV-2 alpha, beta, and gamma variants (B.1.1.7, B.1.351, and P.1 lineages, respectively) are of great significance in that they contain several mutations that increase their transmission rates as evident from clinical reports. …”
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Kefir exhibits anti‑proliferative and pro‑apoptotic effects on colon adenocarcinoma cells with no significant effects on cell migration and invasion
Published 2014“…Results from RT‑PCR showed that kefir decreases the expression of transforming growth factor α (TGF‑α); and transforming growth factor‑β1 (TGF‑β1) in HT‑29 cells. …”
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Daucus carota pentane-based fractions arrest the cell cycle and increase apoptosis in MDA-MB-231 breast cancer cells
Published 2014“…The increase in apoptosis in response to treatment was also apparent in the increase in BAX and the decrease in Bcl-2 levels as well as the proteolytic cleavage of both caspase-3 and PARP as revealed by Western blot. …”
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Research Based Pedagogy to Enhance Quality of Learning: A Study Among Selected Higher Education Institutions in the UAE
Published 2024“…Research Based Pedagogy has become the teaching and learning approaches adopted by the universities and higher education institutions in the UAE. Research Based Pedagogy is referred to as a significant concept that would facilitate in creating research culture and to graduate students with high cognitive thinking order. …”
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Examining the Use of Generative Artificial Intelligence in Higher Education and Its Impact on Social Sustainability: An Integrated Model of UTAUT2 and T-EESST
Published 2024“…In this research, the author assesses and evaluates the degree to which the higher education (HE) sector has embraced generative artificial intelligence (GenAI), primarily focusing on the adoption and application of GenAI and its implications for social sustainability. …”
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IMPACT OF THE UAE NATIONAL SERVICE ON ACADEMIC ACHIEVEMENT AMONG COLLEGE STUDENTS
Published 2021“…The main focus of this study was to investigate the influence of the National Service programme in the UAE among the post-Secondary school Emirati youth on their academic development at higher learning institutions and hence career development in the future. …”
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Enhancing Thermal Comfort for the Revitalization of Pedestrian-Friendly Shopping Arcades in Dubai, UAE
Published 2025“…Using ENVI-met software, simulations are conducted in three stages: urban materials, building facade materials, and vegetation and landscaping, encompassing thirteen different combinations to examine four key aspects: temperature, humidity, wind speed, and PMV value, which significantly affect outdoor thermal comfort. The most favorable cases are selected from each phase, and the final reduction in temperature and PMV values of the optimized case indicates a substantial decrease of 3.76 degrees Celsius in air temperature post-implementation of passive design strategies. …”
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Optimisation of PV Cleaning Practices: Comparison Between Performance Based and Periodic Based Approaches
Published 2018“…Higher relative humidity, drier desert climates, larger dust particles/concentration, and lower PV panel tilt angle are all examples of how soiling or its effects are increased. …”
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The relationship between emotional intelligence and organizational commitment among nurses working in governmental hospitals in Jordan
Published 2023“…Male nurses, widowed nurses, and nurses with higher postgraduate qualifications demonstrated significantly higher levels of emotional intelligence and organizational commitment than female nurses, single nurses, and nurses with undergraduate degrees (p < 0.05).…”
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Effect of clinical hyperthyroidism and hypothyroidism on patent diabetes. 59 cases
Published 1983“…This incidence was significantly higher than the calculated probability of the two diseases occurring by chance in the same patient. …”
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β-2-himachalen-6-ol protects against skin cancer development in vitro and in vivo
Published 2017“…A significant decrease in protein levels of p53 and Bcl-2 and a significant increase in p21 and Bax were observed. …”
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