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Notch Signaling Inhibition by LY411575 Attenuates Osteoblast Differentiation and Decreased Ectopic Bone Formation Capacity of Human Skeletal (Mesenchymal) Stem Cells
Published 2019“…Among the tested molecules, LY411575, a potent γ-secretase and Notch signaling inhibitor, exhibited significant inhibitory effects on osteoblastic differentiation of hBMSCs manifested by reduced ALP activity, mineralized matrix formation, and decreased osteoblast-specific gene expression as well as in vivo ectopic bone formation. …”
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Significance of microscopically incomplete resection margin after esophagectomy for esophageal cancer
Published 2016“…In R1 patients adjuvant therapy improved survival and reduced distant recurrence however failed to affect locoregional recurrence. …”
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A slow but steady nanoLuc: R162A mutation results in a decreased, but stable, nanoLuc activity
Published 2024“…In this regard, engineering of brighter bioluminescent proteins, i.e. luciferases, has played a significant role. This is acutely exemplified by the engineering of the NLuc <u>luciferase</u>, which is small in size and displays much enhanced bioluminescence and<u> thermal stability</u> compared to previously available luciferases. …”
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Small molecule inhibition of stat3 enhances survival in mice with intracerebral melanoma
Published 2008Get full text
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Effects of Autonomous Vehicles on Freeway Traffic Performance
Published 2018Get full text
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Intelligent Fusion of Deep Features for Improved Waste Classification
Published 2020“…Moreover, we also evaluate the performance of the individual deep models, and compare our results against state-of-the-art methods demonstrating a significant improvement of 3.58% over state-of-the-art.…”
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Suppression of Unstable Flow by Using Rough Surfaces at Small Mass Flow Rates in a Radial Diffuser
Published 2006Get full text
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Optimizing the number of players and training bout durations in soccer small‐sided games: Effects on mood balance and technical performance
Published 2025“…Therefore, coaches should consider longer continuous bouts when planning SSGs‐based training to significantly decrease TMD and enhance technical‐tactical performance in soccer SSGs.…”
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Improving the Performance Measurement Using Overall Equipment Effectiveness (OEE) in Borouge
Published 2023“…But This research needs to make improvement on these components to increase the value of OEE. …”
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Diabetic Foot Ulcer Detection: Combining Deep Learning Models for Improved Localization
Published 2024“…The performances of diverse cutting-edge model architectures used in this study complement each other, leading to more generalized and improved results when combined in an ensemble. Our WBF-based approach combining YOLOv8m and FRCNN-ResNet101 achieves a mean average precision (mAP) score of 86.4% at the IoU threshold of 0.5 on the DFUC2020 dataset, significantly outperforming the former benchmark by 12.4%. …”
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Numerical Simulations of Drag-Reducing Devices for Ground Vehicles
Published 2013Get full text
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Voiding function improves under long-term testosterone treatment (TTh) in hypogonadal men, independent of prostate size
Published 2023“…</p><h3>Results</h3><p dir="ltr">Prior to TTh interruption, it was observed that testosterone stimulation improved the men’s IPSS, AMS and post-voiding residual bladder volume, while their prostate volume significantly increased. …”
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Optimizing microgrid efficiency: Coordinating commercial and residential demand patterns with shared battery energy storage
Published 2024“…Unlike previous studies that primarily focused on cost and reliability, this research fills a significant gap in the literature by investigating the optimization of load demands patterns. …”