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Changes in the burden and underlying causes of heart failure in the Eastern Mediterranean Region, 1990–2019: an analysis of the Global Burden of Disease Study 2019
Published 2023“…Among all causes of HF in 2019, ischemic heart disease accounted for the highest age-standardised prevalence and YLDs, followed by hypertensive heart disease. …”
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Detection of statistically significant network changes in complex biological networks
Published 2017“…</p><h3>Methods</h3><p dir="ltr">In this paper, we propose an improvement over the state-of-the-art based on the Generalized Hamming Distance adopted for evaluating the topological difference between two networks and estimating its statistical significance. …”
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Board changes and CEO turnover
Published 2014“…For firms that decrease independence, the CEO turnover performance sensitivity significantly decreases following SOX. …”
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A slow but steady nanoLuc: R162A mutation results in a decreased, but stable, nanoLuc activity
Published 2024“…<p dir="ltr">NanoLuc (NLuc) <u>luciferase</u> has found extensive application in designing a range of <u>biologica</u><u>l</u><u> assays,</u> including <u>gene expression analysis</u>, protein-protein interaction, and protein conformational changes due to its enhanced brightness and small size. …”
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Notch Signaling Inhibition by LY411575 Attenuates Osteoblast Differentiation and Decreased Ectopic Bone Formation Capacity of Human Skeletal (Mesenchymal) Stem Cells
Published 2019“…Global gene expression profiling of LY411575-treated cells revealed changes in multiple signaling pathways, including focal adhesion, insulin, TGFβ, IL6, and Notch signaling, and decreased the expression of genes associated with functional categories of tissue development. …”
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Vocal Changes in Patients With Polycystic Ovary Syndrome
Published 2011“…There was no statistically significant difference in the acoustic parameters except for an increase in the relative average perturbation (P value = 0.035) and a decrease in maximum phonation time (P value = 0.001) in patients with PCOS. …”
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Stemming cardiovascular diseases in Qatar
Published 2015“…The importance of diabetes as a risk factor, however, was found to be higher than other countries in the Gulf region and significantly higher than the US.</p><p>“Public health officials should design programmes to improve the prevention, diagnosis, and management of risk factors such as diabetes and hypertension,” says Christos, as well as work on effective awareness campaigns to create a culture of preventive health in Qatar.…”
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Salvia libanotica improves glycemia and serum lipid profile in rats fed a high fat diet
Published 2015“…Additionally, the plant extract intake produced a significant improvement in serum HDL (34.4 ± 2.4 in GIII vs. 27.2 ± 1.9 mg/dl in controls) and HDL/LDL cholesterol ratio (2.79 ± 0.32 in GII and 3.02 ± 0.31 in GIII vs. 1.74 ± 0.18 in controls), as well as a decrease in abdominal fat. …”
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Essays on the effect of excess compensation and governance changes on firm value
Published 2012“…This dissertation consists of three essays on the effect of excess compensation and corporate governance changes on the firm’s performance. The first paper utilizes a cost minimization stochastic frontier approach to investigate the efficiency of director total compensation. …”
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Olodaterol for the treatment of chronic obstructive pulmonary disease
Published 2016“…In 48- and 6-week Phase III clinical trials of olodaterol evaluating various lung function and symptomatic outcomes in patients with moderate to very severe COPD, olodaterol use was associated with significant improvements in spirometry outcomes, such as postbronchodilator forced expiratory volume in one second (FEV1), as well as dyspnea severity and quality-of-life measures. …”
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The efficacy of colchicine in the management of coronavirus disease 2019
Published 2020“…If colchicine proved to be effective, it would be a significant milestone in the management of COVID-19, a disease with limited available therapeutic options.…”
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Metabolomics of Dynamic Changes in Insulin Resistance Before and After Exercise in PCOS
Published 2019“…While compering within the groups, no significant changes in the amino acid levels before and after exercise were observed. …”
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Breast Disease-Related Educational Outcomes at the University of Florida
Published 2000“…Limiting breast surgery to a single service does not appear to improve resident accumulation and retention of breast disease-related knowledge. …”
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Conceptual Skills in Leading Change: A Competence Approach to Public Sector Leadership
Published 2019“…Leaders’ capacity to think about abstract and complex ideas has long been acknowledged as essential to leadership tasks such as planning and analysis; however, because conceptualisation is often ambiguous and difficult to understand, many frameworks of leadership and change lack clarity on the actual significance of leaders’ conceptual skills when leading change. …”
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Insulin detemir in combination with oral antidiabetic drugs improves glycemic control in persons with type 2 diabetes in Near East countrie
Published 2017“…The percentage of persons who achieved the target of HbA1c<7% increased from .7% at baseline to 39% at week 24. Mean FPG decreased significantly from 213.7 ± 60.1 mg/dL to 120.3 ± 25.7 mg/dL (P<.001), and mean PPG from 271 ± 65.3 mg/dL to 158.1 ± 36.4 mg/dL (P<.0001). …”
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Swimming exercise improves short‐ and long‐term memories: Time‐course changes
Published 2021“…In this investigation, changes in the spatial hippocampal memory following a time-course of swimming exercise training were examined. …”
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The effect of self-reported flossing behavior on cardiovascular disease events and mortality Findings from the 2009-2016 National Health and Nutrition Examination Surveys
Published 2025“…Participants in the not flossing group had significantly elevated CRP levels, even after multivariable adjustments. …”
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