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mediate » mediated (Expand Search), mediates (Expand Search), immediate (Expand Search)
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Detection of statistically significant network changes in complex biological networks
Published 2017“…</p><h3>Methods</h3><p dir="ltr">In this paper, we propose an improvement over the state-of-the-art based on the Generalized Hamming Distance adopted for evaluating the topological difference between two networks and estimating its statistical significance. …”
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Cytotoxicity of Arginine Deprivation to AML Cells is Mediated by Autophagy
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Stemming cardiovascular diseases in Qatar
Published 2015“…The importance of diabetes as a risk factor, however, was found to be higher than other countries in the Gulf region and significantly higher than the US.</p><p>“Public health officials should design programmes to improve the prevention, diagnosis, and management of risk factors such as diabetes and hypertension,” says Christos, as well as work on effective awareness campaigns to create a culture of preventive health in Qatar.…”
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Molecular Mechanisms of Adiponectin-Induced Attenuation of Mechanical Stretch-Mediated Vascular Remodeling
Published 2020“…Stretching the RPV also significantly increased ROS generation after 1 hour, whereas APN significantly decreased mechanical stretch-induced ROS production. …”
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Salvia libanotica improves glycemia and serum lipid profile in rats fed a high fat diet
Published 2015“…Additionally, the plant extract intake produced a significant improvement in serum HDL (34.4 ± 2.4 in GIII vs. 27.2 ± 1.9 mg/dl in controls) and HDL/LDL cholesterol ratio (2.79 ± 0.32 in GII and 3.02 ± 0.31 in GIII vs. 1.74 ± 0.18 in controls), as well as a decrease in abdominal fat. …”
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Olodaterol for the treatment of chronic obstructive pulmonary disease
Published 2016“…In 48- and 6-week Phase III clinical trials of olodaterol evaluating various lung function and symptomatic outcomes in patients with moderate to very severe COPD, olodaterol use was associated with significant improvements in spirometry outcomes, such as postbronchodilator forced expiratory volume in one second (FEV1), as well as dyspnea severity and quality-of-life measures. …”
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The efficacy of colchicine in the management of coronavirus disease 2019
Published 2020“…If colchicine proved to be effective, it would be a significant milestone in the management of COVID-19, a disease with limited available therapeutic options.…”
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Waterpipe Tobacco Smoke Nicotine Mediates Resilience to Chronic Stress by Activating BDNF Signaling
Published 2020“…Even though initially, WTS decreased anxiety-like behaviors it was found that prolonged exposure after the completion of CSDS significantly induced anxiety-like behaviors. …”
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Breast Disease-Related Educational Outcomes at the University of Florida
Published 2000“…Limiting breast surgery to a single service does not appear to improve resident accumulation and retention of breast disease-related knowledge. …”
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Arginine Deprivation in AML Cells Induces Ferroptosis, a Type of Autophagy-Mediated Cell Death
Published 2023“…Scavenging ROS using NAC significantly decreases cell death but has minimal effect on autophagy activation, suggesting that the accumulation of ROS is downstream of autophagy activation but upstream of cell death. …”
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Dihydromyricetin and Salvianolic acid B inhibit alpha-synuclein aggregation and enhance chaperone-mediated autophagy
Published 2019“…Cells were co-transfected with a C-terminal modified α-synuclein (SynT) and synphilin-1, and then treated with DHM (10 μM) and Sal B (50 μM) 16 hours after transfection; levels of α-synuclein aggregation decreased significantly (68% for DHM and 75% for Sal B). …”
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The effect of self-reported flossing behavior on cardiovascular disease events and mortality Findings from the 2009-2016 National Health and Nutrition Examination Surveys
Published 2025“…Participants in the not flossing group had significantly elevated CRP levels, even after multivariable adjustments. …”
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The mediating effect of corporate social responsibility on the relationship between corporate governance and financial performance. (c2016)
Published 2016“…Empirical evidence of this quantitative study confirmed the significance of the relationships as well as the mediating effects of CSR.…”
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Hypoxic Stress Induces Complement-Mediated Lysis of Mesenchymal Stem Cells by Downregulating Factor H and CD59
Published 2024“…Mesenchymal stem cells (MSCs) secrete Factor H and express CD59 to protect themselves from complement-mediated damage. Severe hypoxia found to decrease the survival chances of MSCs after transplantation; however, little is known about the impact of severe hypoxia on modulating the complement system activity and its effect on MSCs survival. …”
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COVID‐19 effect on patients with noncommunicable diseases: A narrative review
Published 2022“…Physical distancing and lockdown made significant obstacles to populations, particularly healthcare systems. …”