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The Anti-Tumor Agent Sodium Selenate Decreases Methylated PP2A, Increases GSK3βY216 Phosphorylation, Including Tau Disease Epitopes and Reduces Neuronal Excitability in SHSY-5Y Neu...
Published 2019“…Somewhat surprisingly, the catalytically active form, methylated PP2A (mePP2A) was significantly decreased. In close correlation to these data, the phosphorylation state of two substrate proteins, sensitive to PP2A activity, GSK3β and Tau were found to be increased. …”
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A slow but steady nanoLuc: R162A mutation results in a decreased, but stable, nanoLuc activity
Published 2024“…Here, we combined molecular dynamics (MD) simulation and mutational analysis to show that the R162A mutation results in a decreased but stable <u>bioluminescence </u>activity of NLuc in living cells and in vitro. …”
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Decreased Interfacial Dynamics Caused by the N501Y Mutation in the SARS-CoV-2 S1 Spike:ACE2 Complex
Published 2022“…In this regard, the recent SARS-CoV-2 alpha, beta, and gamma variants (B.1.1.7, B.1.351, and P.1 lineages, respectively) are of great significance in that they contain several mutations that increase their transmission rates as evident from clinical reports. …”
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Kefir exhibits anti‑proliferative and pro‑apoptotic effects on colon adenocarcinoma cells with no significant effects on cell migration and invasion
Published 2014“…Results from RT‑PCR showed that kefir decreases the expression of transforming growth factor α (TGF‑α); and transforming growth factor‑β1 (TGF‑β1) in HT‑29 cells. …”
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Daucus carota pentane-based fractions arrest the cell cycle and increase apoptosis in MDA-MB-231 breast cancer cells
Published 2014“…The increase in apoptosis in response to treatment was also apparent in the increase in BAX and the decrease in Bcl-2 levels as well as the proteolytic cleavage of both caspase-3 and PARP as revealed by Western blot. …”
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Data-Driven Electricity Demand Modeling for Electric Vehicles Using Machine Learning
Published 2024Get full text
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Factors Determining SMEs Intention to Access Alternative Financing in Emerging Markets: Evidence from the UAE
Published 2023“…Small and Medium Enterprises (SMEs) play a crucial role in driving economic growth, fostering innovation, and creating employment opportunities in the UAE. Despite their significance, SMEs often face a persistent challenge namely the funding gap. …”
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Assessment and Performance Analysis of Machine Learning Techniques for Gas Sensing E-nose Systems
Published 2021Get full text
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Hyperspectral-physiological based predictive model for transpiration in greenhouses under CO<sub>2</sub> enrichment
Published 2023“…In this work, a data-driven predictive model is proposed for the estimation of short-term transpiration (mmol/m<sup>2</sup>.s) for cucumber crops grown in greenhouses with CO<sub>2</sub> enrichment. Three machine learning models were investigated for transpiration modelling and prediction: deep neural networks (DNN), extreme gradient boosting (XGBoost), and support vector machine regression (SVR). …”
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Classification of Cognitive Workload Levels under Vague Visual Stimulation
Published 2016Get full text
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SARS‐CoV‐2 infection and effects of age, sex, comorbidity, and vaccination among older individuals: A national cohort study
Published 2023“…<h3>Background</h3><p dir="ltr">We investigated the contribution of age, coexisting medical conditions, sex, and vaccination to incidence of severe acute respiratory syndrome coronavirus 2 (SARS‐CoV‐2) infection and of severe, critical, or fatal COVID‐19 in older adults since pandemic onset.…”
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Assessing ASEAN’s Liberalized Electricity Markets: The Case of Singapore and the Philippines
Published 2022“…However, there is no significant effect of the electricity market liberalization process on the electricity generated CO<sub>2</sub> emissions. …”
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A comparative analysis to forecast carbon dioxide emissions
Published 2022“…The findings indicate that CO<sub>2</sub> emissions, electrical energy consumption, and GDP have a statistically significant long-term cointegrating relationship. …”
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