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The Anti-Tumor Agent Sodium Selenate Decreases Methylated PP2A, Increases GSK3βY216 Phosphorylation, Including Tau Disease Epitopes and Reduces Neuronal Excitability in SHSY-5Y Neu...
Published 2019“…Somewhat surprisingly, the catalytically active form, methylated PP2A (mePP2A) was significantly decreased. In close correlation to these data, the phosphorylation state of two substrate proteins, sensitive to PP2A activity, GSK3β and Tau were found to be increased. …”
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Integrating data collection optimization into pavement management systems
Published 2017“…Applying the processes to a case study shows significant cost savings associated with this method of roadway testing, as opposed to the current ad hoc methods.…”
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Identifying and Assessing the Significance of Digital Twin Enablers in the Construction Industry
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Staff Development: A Study Into The Significance of Staff Professional Development Programs for Educators and Students Achievement
Published 2011“…This dissertation attempts to study the significance of staff professional development for educators and how it can affect students’ achievement. …”
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A slow but steady nanoLuc: R162A mutation results in a decreased, but stable, nanoLuc activity
Published 2024“…Here, we combined molecular dynamics (MD) simulation and mutational analysis to show that the R162A mutation results in a decreased but stable <u>bioluminescence </u>activity of NLuc in living cells and in vitro. …”
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Decreased Interfacial Dynamics Caused by the N501Y Mutation in the SARS-CoV-2 S1 Spike:ACE2 Complex
Published 2022“…In this regard, the recent SARS-CoV-2 alpha, beta, and gamma variants (B.1.1.7, B.1.351, and P.1 lineages, respectively) are of great significance in that they contain several mutations that increase their transmission rates as evident from clinical reports. …”
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Kefir exhibits anti‑proliferative and pro‑apoptotic effects on colon adenocarcinoma cells with no significant effects on cell migration and invasion
Published 2014“…Results from RT‑PCR showed that kefir decreases the expression of transforming growth factor α (TGF‑α); and transforming growth factor‑β1 (TGF‑β1) in HT‑29 cells. …”
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Curricular integration of the pharmacists' patient care process
Published 2021“…Results The findings indicate that the PPCP-based laboratory significantly improved students' perception of their preparedness to apply a standardized pharmacist care process to verify prescriptions, to collect relevant patient information, and to develop an individual patient-centered care plan. …”
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Daucus carota pentane-based fractions arrest the cell cycle and increase apoptosis in MDA-MB-231 breast cancer cells
Published 2014“…The increase in apoptosis in response to treatment was also apparent in the increase in BAX and the decrease in Bcl-2 levels as well as the proteolytic cleavage of both caspase-3 and PARP as revealed by Western blot. …”
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The Impact of Artificial Intelligence on Institutional Recruitment and Selection Processes
Published 2024“…The participants also perceived the negative impact of key members on recruitment and selection processes at a high level of significance (p ≤ 0.05). …”
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Evaluation of the effects of standardization process of severe trauma treatment in China
Published 2015“…Treatment outcomes were compared between before and one year after the implementation of standardization processes.</p><h3 dir="ltr">Results</h3><p dir="ltr">The outcomes of a total of 74,615 and 12051 cases of severe trauma were collected from 12 hospitals before the implementation of standardization processes. …”
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Industrial Processes Performance Improvement using Six Sigma Principles and Tools
Published 2019“…In this project, TQM and Six Sigma DMAIC methodology were used to improve the process of paper bag making to make sure that the output of the manufacturing process meets the demands of customers. …”
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Operations management of outpatient chemotherapy process: An optimization-oriented comprehensive review
Published 2022“…Therefore, outpatient chemotherapy process (OCP) optimization has attracted the attention of operations management scholars. …”
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Managing change process: A case study of a private school in Sharjah
Published 2016“…The significance of change process management increases as the modern world trends of education and learning require a change. …”
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Business Process Re-engineering Strategies for United Arab Emirates’ Public Organizations
Published 2022Get full text
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