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One Dimensional Seismic Site Response Analysis of United Arab Emirates
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The Anti-Tumor Agent Sodium Selenate Decreases Methylated PP2A, Increases GSK3βY216 Phosphorylation, Including Tau Disease Epitopes and Reduces Neuronal Excitability in SHSY-5Y Neu...
Published 2019“…Somewhat surprisingly, the catalytically active form, methylated PP2A (mePP2A) was significantly decreased. In close correlation to these data, the phosphorylation state of two substrate proteins, sensitive to PP2A activity, GSK3β and Tau were found to be increased. …”
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Scaffold‑based 3D cell culture models in cancer research
Published 2024“…Three-dimensional (3D) cell cultures have emerged as valuable tools in cancer research, offering significant advantages over traditional two-dimensional (2D) cell culture systems. …”
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Experimental validation of numerical model for thermomechanical performance of material extrusion additive manufacturing process: Effect of infill design & density
Published 2023“…The current practices of the experimental optimization process require significant resources, which can be limited through numerical modeling and simulation techniques. …”
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A slow but steady nanoLuc: R162A mutation results in a decreased, but stable, nanoLuc activity
Published 2024“…Here, we combined molecular dynamics (MD) simulation and mutational analysis to show that the R162A mutation results in a decreased but stable <u>bioluminescence </u>activity of NLuc in living cells and in vitro. …”
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Decreased Interfacial Dynamics Caused by the N501Y Mutation in the SARS-CoV-2 S1 Spike:ACE2 Complex
Published 2022“…In this regard, the recent SARS-CoV-2 alpha, beta, and gamma variants (B.1.1.7, B.1.351, and P.1 lineages, respectively) are of great significance in that they contain several mutations that increase their transmission rates as evident from clinical reports. …”
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Type 2 Diabetes Mellitus Automated Risk Detection Based on UAE National Health Survey Data: A Framework for the Construction and Optimization of Binary Classification Machine Learn...
Published 2020“…A special consideration was given to data pre-processing and dimensionality reduction such Chi Squared (CS) and Recursive Feature Elimination (RFE) to improve progressively the proposed models performance. …”
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Kefir exhibits anti‑proliferative and pro‑apoptotic effects on colon adenocarcinoma cells with no significant effects on cell migration and invasion
Published 2014“…Results from RT‑PCR showed that kefir decreases the expression of transforming growth factor α (TGF‑α); and transforming growth factor‑β1 (TGF‑β1) in HT‑29 cells. …”
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UGA-GAN: Unified Geometry-Aware GAN for Enhanced Training and Generation of High-Dimensional Data
Published 2025“…These results highlight the potential of UGA-GAN to significantly improve high-dimensional data generation tasks in domains such as medical imaging, video generation, and 3D object synthesis. …”
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UniBFS: A novel uniform-solution-driven binary feature selection algorithm for high-dimensional data
Published 2024“…Despite its importance, the constantly increasing search space of high-dimensional datasets poses significant challenges to FS methods, including issues like the "curse of dimensionality," susceptibility to local optima, and high computational and memory costs. …”
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Daucus carota pentane-based fractions arrest the cell cycle and increase apoptosis in MDA-MB-231 breast cancer cells
Published 2014“…The increase in apoptosis in response to treatment was also apparent in the increase in BAX and the decrease in Bcl-2 levels as well as the proteolytic cleavage of both caspase-3 and PARP as revealed by Western blot. …”
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The effectiveness of physical models in teaching anatomy
Published 2016“…There are various educational methods used in anatomy teaching. While three dimensional (3D) visualization technologies are gaining ground due to their ever-increasing realism, reports investigating physical models as a low-cost 3D traditional method are still the subject of considerable interest. …”
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Contagion effects in a chartist–fundamentalist model with time delays
Published 2007“…Numerical solutions to the model show that asset prices exhibit significant persistence as a result of the coupling to the log-periodic market index. …”
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