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The Anti-Tumor Agent Sodium Selenate Decreases Methylated PP2A, Increases GSK3βY216 Phosphorylation, Including Tau Disease Epitopes and Reduces Neuronal Excitability in SHSY-5Y Neu...
Published 2019“…Somewhat surprisingly, the catalytically active form, methylated PP2A (mePP2A) was significantly decreased. In close correlation to these data, the phosphorylation state of two substrate proteins, sensitive to PP2A activity, GSK3β and Tau were found to be increased. …”
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A slow but steady nanoLuc: R162A mutation results in a decreased, but stable, nanoLuc activity
Published 2024“…Here, we combined molecular dynamics (MD) simulation and mutational analysis to show that the R162A mutation results in a decreased but stable <u>bioluminescence </u>activity of NLuc in living cells and in vitro. …”
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Decreased Interfacial Dynamics Caused by the N501Y Mutation in the SARS-CoV-2 S1 Spike:ACE2 Complex
Published 2022“…In this regard, the recent SARS-CoV-2 alpha, beta, and gamma variants (B.1.1.7, B.1.351, and P.1 lineages, respectively) are of great significance in that they contain several mutations that increase their transmission rates as evident from clinical reports. …”
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Kefir exhibits anti‑proliferative and pro‑apoptotic effects on colon adenocarcinoma cells with no significant effects on cell migration and invasion
Published 2014“…Results from RT‑PCR showed that kefir decreases the expression of transforming growth factor α (TGF‑α); and transforming growth factor‑β1 (TGF‑β1) in HT‑29 cells. …”
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Dimensional and positional temporomandibular joint osseous characteristics in normodivergent facial patterns with and without temporomandibular disorders
Published 2023“…</p><h3>Conclusion</h3><p dir="ltr">There were significant differences between the patients with and without temporomandibular joint disorders in terms of mandibular fossa positions and height as well as condylar positions and inclinations in horizontal and vertical planes together with reduced condylar height and reduced posterior and superior joint spaces in the temporomandibular disorders patients.…”
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Prediction of critical total drawdown in sand production from gas wells: Machine learning approach
Published 2023“…The effects of all independent variables on the CTD are displayed in three-dimensional plots and showed significant interactions.…”
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Early gas kick detection in vertical wells via transient multiphase flow modelling: A review
Published 2020“…Early gas-kick prediction and analysis through dynamic multiphase flow can lead to significant progress in detection and controlling of High Pressure High Temperature (HPHT) drilling of deep wells, which is vital to prevent gas blowout risk. …”
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Daucus carota pentane-based fractions arrest the cell cycle and increase apoptosis in MDA-MB-231 breast cancer cells
Published 2014“…The increase in apoptosis in response to treatment was also apparent in the increase in BAX and the decrease in Bcl-2 levels as well as the proteolytic cleavage of both caspase-3 and PARP as revealed by Western blot. …”
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Temporomandibular joint osseous characteristics in skeletal short and long facial types with and without temporomandibular disorders: A three-dimensional comparative study
Published 2025“…The DDR/DDWR group with a long facial skeletal pattern exhibited significant variations in condyle dimensions, orientations, and positions, showing more anterior and inferior condylar placements, as well as differences in joint spaces. …”
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In-situ grown ternary metal hydroxides@3D oriented crumpled V₂C MXene sheets for improved electrocatalytic oxygen evolution reaction
Published 2024“…Besides, as found in FESEM morphological investigation, the well-dispersed NiFeCr multi-transition metal hydroxides are immobilized on open pores like structure of V₂C-MX facilitate thoroughly accessible active sites. …”
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Efficient Photocatalytic Degradation of Organic Dyes by AgNPs/TiO<sub>2</sub>/Ti<sub>3</sub>C<sub>2</sub>T<sub><em>x</em></sub> MXene Composites under UV and Solar Light
Published 2021“…<p dir="ltr">Due to their broad applications in various industrial activities, and their well-known negative impacts on the aquatic environment, organic dyes have been continuously identified as serious threat to the quality of ecosystems. …”
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Deep learning-based beat-to-beat arterial blood pressure estimation using distant radar signals
Published 2025“…This breakthrough offers significant advantages, facilitating continuous ABP monitoring without the need for invasive procedures or cumbersome wearable sensors.…”
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An Optimized Feature Selection Technique in Diversified Natural Scene Text for Classification Using Genetic Algorithm
Published 2021“…The obtained results proved that the proposed algorithm performs well while classifying textual and non-textual region with better accuracy than benchmark state-of-the-art algorithms.…”
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Scalable Nonparametric Supervised Learning for Streaming and Massive Data: Applications in Healthcare Monitoring and Credit Risk
Published 2025“…We propose an offline kernel-based classifier enhanced by Batch Principal Component Analysis (PCA) for dimensionality reduction to mitigate the “curse of dimensionality”. …”
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