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increased » increase (Expand Search)
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Serum Vitamin D Concentration ≥75 nmol/L Is Related to Decreased Cardiometabolic and Inflammatory Biomarkers, Metabolic Syndrome, and Diabetes; and Increased Cardiorespiratory Fitn...
Published 2020“…We investigated the relationship between serum 25(OH)D and metabolic syndrome (MetS), diabetes, cardiometabolic biomarkers, and cardiorespiratory fitness (CRF) in US adults using clinical cut points recommended by health organizations. Data from USA’s National Health and Nutrition Examination Surveys were used. …”
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The Anti-Tumor Agent Sodium Selenate Decreases Methylated PP2A, Increases GSK3βY216 Phosphorylation, Including Tau Disease Epitopes and Reduces Neuronal Excitability in SHSY-5Y Neu...
Published 2019“…Somewhat surprisingly, the catalytically active form, methylated PP2A (mePP2A) was significantly decreased. In close correlation to these data, the phosphorylation state of two substrate proteins, sensitive to PP2A activity, GSK3β and Tau were found to be increased. …”
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L1-CAM knock-down radiosensitizes neuroblastoma IMR-32 cells by simultaneously decreasing MycN, but increasing PTEN protein expression
Published 2016“…Notably, radiotherapy (2 Gy) of the IMR-32 cells led to significant upregulation of both L1-CAM and MycN, which was abrogated with L1-CAM KD in our cells. …”
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Systematic analysis of healthcare big data analytics for efficient care and disease diagnosing
Published 2022“…It contains a gigantic amount of data, especially a plethora of data types that has been significantly useful in diverse research domains. …”
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Prostate cancer burden in South Asia: A systematic analysis of global burden of disease data (1990–2021)
Published 2024“…<h3>Objectives</h3><p dir="ltr">The objectives of this study were to analyze trends in prostate cancer incidence, incidence, mortality, and disability‐adjusted life years (DALYs) from 1990 to 2021 via data from the Global Burden of Disease (GBD) study in South Asia. …”
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Cutting‐edge technologies for detecting and controlling fish diseases: Current status, outlook, and challenges
Published 2024“…However, the industry is facing several difficulties, including infectious diseases, the most significant limiting factor for aquaculture expansion. …”
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PFDI: a precise fruit disease identification model based on context data fusion with faster-CNN in edge computing environment
Published 2023“…This research presents a precise fruit disease identification model based on context data fusion with Faster-CNN in an edge computing environment. …”
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A Comprehensive Analysis of Healthcare Big Data Management, Analytics and Scientific Programming
Published 2020“…Scientific programming play a significant role to overcome the existing issues and future problems involved in the management of large scale data in healthcare, such as by assisting in the processing of huge data volumes, complex system modelling, and sourcing derivations from healthcare data and simulations. …”
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A slow but steady nanoLuc: R162A mutation results in a decreased, but stable, nanoLuc activity
Published 2024“…Here, we combined molecular dynamics (MD) simulation and mutational analysis to show that the R162A mutation results in a decreased but stable <u>bioluminescence </u>activity of NLuc in living cells and in vitro. …”
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Association of coronary artery disease and chronic kidney disease in Lebanese population
Published 2015“…This correlation remained highly significant despite considerable inter-patient variability and was at its highest at the most advanced stages of both diseases. …”
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Decreased Interfacial Dynamics Caused by the N501Y Mutation in the SARS-CoV-2 S1 Spike:ACE2 Complex
Published 2022“…In this regard, the recent SARS-CoV-2 alpha, beta, and gamma variants (B.1.1.7, B.1.351, and P.1 lineages, respectively) are of great significance in that they contain several mutations that increase their transmission rates as evident from clinical reports. …”
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Endocardial-Epicardial Catheter Ablation Versus Endocardial Catheter Ablation Alone for Ventricular Arrhythmia in Patients With Structural Heart Disease (Meta-Analysis of Reconstru...
Published 2023“…However, there was no significant difference with non-ICM (HR 0.440, 0.55 to 0.87, p <0.33). …”
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Kefir exhibits anti‑proliferative and pro‑apoptotic effects on colon adenocarcinoma cells with no significant effects on cell migration and invasion
Published 2014“…Results from RT‑PCR showed that kefir decreases the expression of transforming growth factor α (TGF‑α); and transforming growth factor‑β1 (TGF‑β1) in HT‑29 cells. …”
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Epigenetic analysis of Paget’s disease of bone identifies differentially methylated loci that predict disease status
Published 2021“…This study aims to characterize PDB-associated changes in DNA methylation profiles in patients’ blood. Meta-analysis of data from the discovery and cross-validation set, each comprising 116 PDB cases and 130 controls, revealed significant differences in DNA methylation at 14 CpG sites, 4 CpG islands, and 6 gene-body regions. …”
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Parkinson’s disease and schizophrenia interactomes contain temporally distinct gene clusters underlying comorbid mechanisms and unique disease processes
Published 2024“…<p dir="ltr">Genome-wide association studies suggest significant overlaps in Parkinson’s disease (PD) and schizophrenia (SZ) risks, but the underlying mechanisms remain elusive. …”
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Inflammatory Markers and COVID-19 Disease Progression
Published 2023“…</p> <h3>Conclusions</h3> <p>The data suggest a significant association between levels of inflammatory markers and COVID-19 severity. …”
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Olodaterol for the treatment of chronic obstructive pulmonary disease
Published 2016“…Purpose. Published data on the pharmacology, pharmacokinetics, efficacy, and safety of the once-daily, long-acting β2-agonist (LABA) olodaterol are reviewed. …”
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Dietary patterns in cardiovascular diseases prevention and management
Published 2014“…Using data from the national Nutrition and Non-Communicable Disease Risk Factor Survey, we appraised the association of dietary patterns with CVD risk factors among Lebanese adults. …”
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