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The Anti-Tumor Agent Sodium Selenate Decreases Methylated PP2A, Increases GSK3βY216 Phosphorylation, Including Tau Disease Epitopes and Reduces Neuronal Excitability in SHSY-5Y Neu...
Published 2019“…Somewhat surprisingly, the catalytically active form, methylated PP2A (mePP2A) was significantly decreased. In close correlation to these data, the phosphorylation state of two substrate proteins, sensitive to PP2A activity, GSK3β and Tau were found to be increased. …”
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A slow but steady nanoLuc: R162A mutation results in a decreased, but stable, nanoLuc activity
Published 2024“…Here, we combined molecular dynamics (MD) simulation and mutational analysis to show that the R162A mutation results in a decreased but stable <u>bioluminescence </u>activity of NLuc in living cells and in vitro. …”
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Decreased Interfacial Dynamics Caused by the N501Y Mutation in the SARS-CoV-2 S1 Spike:ACE2 Complex
Published 2022“…In this regard, the recent SARS-CoV-2 alpha, beta, and gamma variants (B.1.1.7, B.1.351, and P.1 lineages, respectively) are of great significance in that they contain several mutations that increase their transmission rates as evident from clinical reports. …”
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Kefir exhibits anti‑proliferative and pro‑apoptotic effects on colon adenocarcinoma cells with no significant effects on cell migration and invasion
Published 2014“…Results from RT‑PCR showed that kefir decreases the expression of transforming growth factor α (TGF‑α); and transforming growth factor‑β1 (TGF‑β1) in HT‑29 cells. …”
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Investigating the Effect of Patient-Related Factors on Computed Tomography Radiation Dose Using Regression and Correlation Analysis
Published 2024“…Moreover, the study investigated the correlation between the different CT dose indices. Using linear regression models and Pearson correlation, the study found that all CT dose indices correlate with BMI and weight in all CT exams with varying degrees as opposed to age, which did not demonstrate any significant correlation with any of the CT dose indices across all CT exams. …”
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Daucus carota pentane-based fractions arrest the cell cycle and increase apoptosis in MDA-MB-231 breast cancer cells
Published 2014“…The increase in apoptosis in response to treatment was also apparent in the increase in BAX and the decrease in Bcl-2 levels as well as the proteolytic cleavage of both caspase-3 and PARP as revealed by Western blot. …”
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Assessment and Performance Analysis of Machine Learning Techniques for Gas Sensing E-nose Systems
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A cross-cultural study of high-altitude botanical resources among diverse ethnic groups in Kashmir Himalaya, India
Published 2023“…This may be due to the fact that both ethnic groups share a common geographical landscape and are exogamous to each other. We identified key indicator species used by different ethnic groups with significant (p ≤ 0.05) values. …”
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A geographic information system method to generate long term regional solar radiation resource maps: enhancing decision-making
Published 2024“…Long-term monthly maps of daily total solar radiation have been produced which consist of 12 monthly maps for global horizontal irradiance (GHI) and 12 monthly maps for direct normal irradiance (DNI) for each month of the year. A significant improvement of 9.15% and 9.32% in GHI and DNI estimation has been observed after calibration, which brings down the Normalized Root Mean Square Error (NRMSE) to 4% and 11.70% for GHI and DNI respectively as compared to the non-calibrated satellite data estimation.…”
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The Impact of Non-Interest Income on Commercial Bank Profitability in the Middle East and North Africa (MENA) Region
Published 2024“…The analysis is based on data from 40 banks (5 banks from each country) operating in Bahrain, Egypt, Jordan, Kuwait, Oman, Qatar, Saudi Arabia, and the United Arab Emirates between 2010 and 2022. …”
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Effects of Social Media Use and Dependence on Dietary Intake and Prevalence of Orthorexia in Pregnant and Non-Pregnant Women
Published 2022“…However, social media use was not significantly associated with orthorexia. Regression analyses showed that both social media use (p<0.001) and having a social media account (p=0.023) were predictors of reduced intuitive eating, with social media use being the most significant predictor. …”
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Relationship between Asymmetry Indices, Anthropometric Parameters, and Physical Fitness in Obese and Non-Obese High School Students
Published 2022“…In the second regression analysis, controlling for age, body mass, and BMI, the regression coefficients associated with height (B = −1.692, 95% CI [−3.115, −0.269], p < 0.05] and body fat percentage (B = 0.529, 95% CI [0.075, 0.983], p < 0.05) indicated that with each additional unit of height or body fat percentage, the CMJ AI decreased by 1.692 units and increased by 0.529 units. …”
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Effect of consanguinity on birth weight for gestational age in a developing country
Published 2007“…No significant difference was observed in the decrease in birth weight between the first- and second-cousin marriages. …”
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Using Data Mining and Text Mining Techniques in Predicting the Price of Real Estate Properties in Dubai
Published 2014“…It is found that the results of linear regression prediction have been improved significantly after adding text mining to the experiments. …”
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