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The Anti-Tumor Agent Sodium Selenate Decreases Methylated PP2A, Increases GSK3βY216 Phosphorylation, Including Tau Disease Epitopes and Reduces Neuronal Excitability in SHSY-5Y Neu...
Published 2019“…Somewhat surprisingly, the catalytically active form, methylated PP2A (mePP2A) was significantly decreased. In close correlation to these data, the phosphorylation state of two substrate proteins, sensitive to PP2A activity, GSK3β and Tau were found to be increased. …”
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Nasturtium officinalis water extract. (c2009)
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masterThesis -
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A slow but steady nanoLuc: R162A mutation results in a decreased, but stable, nanoLuc activity
Published 2024“…Here, we combined molecular dynamics (MD) simulation and mutational analysis to show that the R162A mutation results in a decreased but stable <u>bioluminescence </u>activity of NLuc in living cells and in vitro. …”
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Decreased Interfacial Dynamics Caused by the N501Y Mutation in the SARS-CoV-2 S1 Spike:ACE2 Complex
Published 2022“…In this regard, the recent SARS-CoV-2 alpha, beta, and gamma variants (B.1.1.7, B.1.351, and P.1 lineages, respectively) are of great significance in that they contain several mutations that increase their transmission rates as evident from clinical reports. …”
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Anticancer and antioxidant effects of tragopogon porrifolius extract. (c2011)
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masterThesis -
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Kefir exhibits anti‑proliferative and pro‑apoptotic effects on colon adenocarcinoma cells with no significant effects on cell migration and invasion
Published 2014“…Results from RT‑PCR showed that kefir decreases the expression of transforming growth factor α (TGF‑α); and transforming growth factor‑β1 (TGF‑β1) in HT‑29 cells. …”
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Chemical composition, antioxidant and anti-inflammatory activity evaluation of the lebanese propolis extract
Published 2019“…Results: Pathology analysis revealed in the treated group significant reduction of immune cell infiltration and edema. …”
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Choice of specimen’s extraction site affects wound morbidity in laparoscopic colorectal cancer surgery
Published 2022“…MI was used in 90 patients while 78 patients had STI as an extraction site. Demographic and preoperative data is similar for two groups. …”
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Efficacy of Lebanese Cannabis Oil Extract in the Treatment of Folic Acid-Induced Renal Fibrosis in Rats
Published 2023“…In addition, a significant decrease in serum creatinine was observed in groups receiving cannabis extract at the doses of 5 and 10 mg/kg. …”
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masterThesis -
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Therapeutic Effect of Lebanese Cannabis Oil Extract in the Management of Sodium Orthovanadate-Induced Nephrotoxicity in Rats
Published 2023“…All doses of Cannabis oil caused significant decrease in serum urea, as well as in serum creatinine at a dose of 20mg/Kg. …”
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Diversity of protists in dryland habitats of Qatar revealed by environmental metabarcoding
Published 2025“…Protist diversity differed significantly between habitats and among samples, while richness varied significantly between habitats. …”
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Hepatoprotective Effect of Oleuropein-Rich Extract from Olive Leaves against Cadmium-Induced Toxicity in Mice
Published 2020“…Results showed that Cd induced a significant increase in liver injury biomarkers coupled with enhanced lipid peroxidation (MDA) and significant depletion of antioxidants (CAT and SOD). …”
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Daucus carota pentane-based fractions arrest the cell cycle and increase apoptosis in MDA-MB-231 breast cancer cells
Published 2014“…The increase in apoptosis in response to treatment was also apparent in the increase in BAX and the decrease in Bcl-2 levels as well as the proteolytic cleavage of both caspase-3 and PARP as revealed by Western blot. …”
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